Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AA973_RS02545 Genome accession   NZ_CP011485
Coordinates   514813..516597 (-) Length   594 a.a.
NCBI ID   WP_064437496.1    Uniprot ID   -
Organism   Helicobacter pylori strain ausabrJ05     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 509813..521597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA973_RS02515 (AA973_02530) - 510352..510600 (+) 249 WP_000790557.1 RNA-binding protein -
  AA973_RS02520 (AA973_02535) - 510810..511631 (-) 822 WP_064437492.1 glycosyltransferase family 25 protein -
  AA973_RS02525 (AA973_02540) trxB 511843..512778 (-) 936 WP_064437493.1 thioredoxin-disulfide reductase -
  AA973_RS02530 (AA973_02545) trxA 512784..513104 (-) 321 WP_000020204.1 thioredoxin -
  AA973_RS02535 (AA973_02550) - 513192..513536 (-) 345 WP_064437494.1 YraN family protein -
  AA973_RS02540 (AA973_02555) - 513537..514802 (-) 1266 WP_064437495.1 homoserine dehydrogenase -
  AA973_RS02545 (AA973_02560) uvrC 514813..516597 (-) 1785 WP_064437496.1 excinuclease ABC subunit UvrC Machinery gene
  AA973_RS02550 (AA973_02565) - 516598..517059 (-) 462 WP_064437497.1 hypothetical protein -
  AA973_RS02555 (AA973_02570) - 517051..517230 (+) 180 WP_064437498.1 hypothetical protein -
  AA973_RS02560 (AA973_02575) - 517242..517883 (-) 642 WP_064437499.1 ATP-binding cassette domain-containing protein -
  AA973_RS02565 (AA973_02580) - 517885..519195 (-) 1311 Protein_501 glycine betaine ABC transporter substrate-binding protein -
  AA973_RS02570 (AA973_02585) - 519137..519583 (-) 447 WP_064438214.1 hypothetical protein -
  AA973_RS02575 (AA973_02590) motB 519589..520362 (-) 774 WP_064437500.1 flagellar motor protein MotB -
  AA973_RS02580 (AA973_02595) motA 520365..521138 (-) 774 WP_000366185.1 flagellar motor stator protein MotA -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68690.91 Da        Isoelectric Point: 9.6674

>NTDB_id=146259 AA973_RS02545 WP_064437496.1 514813..516597(-) (uvrC) [Helicobacter pylori strain ausabrJ05]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNHRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSGNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGSHKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNEFQKNSYRHYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=146259 AA973_RS02545 WP_064437496.1 514813..516597(-) (uvrC) [Helicobacter pylori strain ausabrJ05]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGCGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAACAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACAAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCATTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAACGCCTTTCTGGCAACTTGCGTTTTGAAGAAGCCCTTATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGGGAGCCATAAAGCCGT
GTTAGTGAAAATGTTTATGCGCGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAACGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATTAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTCAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTCAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGAATTTCAAAAAAACTCTTATCGGCA
CTACCATTTAAAAGGCTCTGATGAATACGCGCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTCGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment