Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AA976_RS04235 Genome accession   NZ_CP011484
Coordinates   887487..889271 (+) Length   594 a.a.
NCBI ID   WP_064436619.1    Uniprot ID   -
Organism   Helicobacter pylori strain CC33C     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 882487..894271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA976_RS04205 (AA976_04220) motB 883209..883982 (+) 774 WP_064436616.1 flagellar motor protein MotB -
  AA976_RS04210 (AA976_04225) - 883979..884425 (+) 447 WP_080471250.1 hypothetical protein -
  AA976_RS04215 (AA976_04230) - 884539..886197 (+) 1659 WP_064436617.1 ABC transporter permease/substrate-binding protein -
  AA976_RS04220 (AA976_04235) - 886201..886842 (+) 642 WP_064436618.1 ATP-binding cassette domain-containing protein -
  AA976_RS04225 (AA976_04240) - 886854..887033 (-) 180 WP_001847249.1 hypothetical protein -
  AA976_RS04230 (AA976_04245) - 887025..887486 (+) 462 WP_000437150.1 hypothetical protein -
  AA976_RS04235 (AA976_04250) uvrC 887487..889271 (+) 1785 WP_064436619.1 excinuclease ABC subunit UvrC Machinery gene
  AA976_RS04240 (AA976_04255) - 889282..890547 (+) 1266 WP_064436620.1 homoserine dehydrogenase -
  AA976_RS04245 (AA976_04260) - 890548..890892 (+) 345 WP_033776423.1 YraN family protein -
  AA976_RS04250 (AA976_04265) trxA 890981..891301 (+) 321 WP_000020189.1 thioredoxin -
  AA976_RS04255 (AA976_04270) trxB 891307..892242 (+) 936 WP_033776422.1 thioredoxin-disulfide reductase -
  AA976_RS04260 (AA976_04275) - 892612..893433 (+) 822 WP_033776421.1 glycosyltransferase family 25 protein -
  AA976_RS04265 (AA976_04280) - 893652..893900 (-) 249 WP_000790560.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68665.84 Da        Isoelectric Point: 9.7561

>NTDB_id=146242 AA976_RS04235 WP_064436619.1 887487..889271(+) (uvrC) [Helicobacter pylori strain CC33C]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNPRSSLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYNQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=146242 AA976_RS04235 WP_064436619.1 887487..889271(+) (uvrC) [Helicobacter pylori strain CC33C]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCATAATAATGAAATCACGCCCA
ACCCTCGCTCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGACATTTTAGACAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTCATTTACAGAGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGTGGGAACAACAAGGCGGT
GTTAGTGAAAATGTTCATGCGCGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATCTTATTGAGC
GCTTGCTCCAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATATAATCAAATGAGCGAATTGCTCACCAGAAGAGCCTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAAGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.459

99.832

0.963

Multiple sequence alignment