Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   AA976_RS00480 Genome accession   NZ_CP011484
Coordinates   89124..89867 (+) Length   247 a.a.
NCBI ID   WP_064436170.1    Uniprot ID   -
Organism   Helicobacter pylori strain CC33C     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 84124..94867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA976_RS00455 (AA976_00455) panD 86279..86632 (+) 354 WP_000142288.1 aspartate 1-decarboxylase -
  AA976_RS00460 (AA976_00460) - 86635..86937 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  AA976_RS00465 (AA976_00465) - 86931..87935 (+) 1005 WP_064436168.1 PDZ domain-containing protein -
  AA976_RS00470 (AA976_00470) comB6 87943..88998 (+) 1056 WP_064436169.1 P-type conjugative transfer protein TrbL Machinery gene
  AA976_RS00475 (AA976_00475) comB7 89014..89127 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  AA976_RS00480 (AA976_00480) comB8 89124..89867 (+) 744 WP_064436170.1 type IV secretion system protein Machinery gene
  AA976_RS00485 (AA976_00485) comB9 89867..90838 (+) 972 WP_064436171.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  AA976_RS00490 (AA976_00490) comB10 90831..91967 (+) 1137 WP_064436172.1 DNA type IV secretion system protein ComB10 Machinery gene
  AA976_RS00495 (AA976_00495) - 92037..93449 (+) 1413 WP_064436173.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  AA976_RS00500 (AA976_00500) gmd 93490..94635 (+) 1146 WP_064436174.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28779.01 Da        Isoelectric Point: 8.9661

>NTDB_id=146233 AA976_RS00480 WP_064436170.1 89124..89867(+) (comB8) [Helicobacter pylori strain CC33C]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALILAIVLISILPLQKT
EHHFVDFLNQDKHYAIVQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
VQSHLEREIHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
VPTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=146233 AA976_RS00480 WP_064436170.1 89124..89867(+) (comB8) [Helicobacter pylori strain CC33C]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGCTGGAAAGGAACCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCGCTTATCTTAGCGATCGTTTTAATCAGTATCCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTGTCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAGTCCCGCT
ATGAACTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAGCCCAAAACAGCATTTAC
GTACAAAGCCATTTAGAAAGAGAGATCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTCACGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GTGCCGACTAACAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment