Detailed information NTG0145906

Bioinformatically predicted

Overview

• Name: radA
• Type: Machinery gene
• Locus tag: AA105_RS10570
• Genome accession: NZ_CP011419
• Coordinates: 2093273..2094643 (-)
• Length: 456 a.a.
• NCBI ID: WP_004298358.1
• Uniprot ID: A0A126UJP8
• Organism: Streptococcus suis strain NSUI002
• Function: homologous recombination (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	2095190..2111080	2093273..2094643	flank	547

Gene organization within MGE regions

Location: 2093273..2111080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AA105_RS10570 (AA105_10590)	radA	2093273..2094643 (-)	1371	WP_004298358.1	DNA repair protein RadA	Machinery gene
AA105_RS10575 (AA105_10595)	-	2094650..2095183 (-)	534	WP_004298356.1	histidine phosphatase family protein	-
AA105_RS10580 (AA105_10600)	-	2095190..2095633 (-)	444	WP_004298354.1	dUTP diphosphatase	-
AA105_RS10585 (AA105_10605)	-	2095731..2096876 (-)	1146	WP_044666645.1	site-specific integrase	-
AA105_RS10590 (AA105_10610)	-	2097047..2097877 (-)	831	WP_013730692.1	KilA-N domain-containing protein	-
AA105_RS10595 (AA105_10615)	-	2098240..2098824 (-)	585	WP_044674473.1	helix-turn-helix transcriptional regulator	-
AA105_RS10600 (AA105_10620)	-	2099031..2099231 (+)	201	WP_044666638.1	helix-turn-helix domain-containing protein	-
AA105_RS10605 (AA105_10625)	-	2099728..2100156 (+)	429	WP_044674475.1	hypothetical protein	-
AA105_RS12405 (AA105_10630)	-	2100156..2100353 (+)	198	WP_044674478.1	hypothetical protein	-
AA105_RS10615 (AA105_10635)	-	2100364..2100549 (+)	186	WP_044686673.1	hypothetical protein	-
AA105_RS10620 (AA105_10640)	-	2100546..2100881 (+)	336	WP_044674480.1	hypothetical protein	-
AA105_RS10625 (AA105_10645)	-	2100874..2101155 (+)	282	WP_044674482.1	hypothetical protein	-
AA105_RS10630 (AA105_10650)	-	2101142..2101960 (+)	819	WP_044674484.1	phage replisome organizer N-terminal domain-containing protein	-
AA105_RS10635 (AA105_10655)	-	2101975..2102835 (+)	861	WP_024417153.1	ATP-binding protein	-
AA105_RS10640 (AA105_10660)	-	2102832..2103290 (+)	459	WP_024417152.1	hypothetical protein	-
AA105_RS10645 (AA105_10665)	-	2103350..2103751 (+)	402	WP_024417151.1	hypothetical protein	-
AA105_RS12320 (AA105_10670)	-	2103803..2104306 (+)	504	WP_024417150.1	hypothetical protein	-
AA105_RS10655 (AA105_10675)	-	2104697..2105128 (+)	432	WP_024417149.1	DUF1492 domain-containing protein	-
AA105_RS10660 (AA105_10680)	-	2105909..2107693 (-)	1785	WP_004298352.1	ABC transporter ATP-binding protein	-
AA105_RS10665 (AA105_10685)	-	2107694..2109400 (-)	1707	WP_004298350.1	ABC transporter ATP-binding protein	-
AA105_RS10670 (AA105_10690)	-	2109393..2109842 (-)	450	WP_004298348.1	MarR family winged helix-turn-helix transcriptional regulator	-
AA105_RS10675 (AA105_10695)	-	2110064..2111080 (+)	1017	WP_004298347.1	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 50002.51 Da
• Isoelectric Point: 6.1911

>NTDB_id=145906 AA105_RS10570 WP_004298358.1 2093273..2094643(-) (radA) [Streptococcus suis strain NSUI002]
MTIAKKKTTFVCQSCEYHSPKYLGRCPNCGSWSSFVEEVEVAEVKNERVSLTGEKTRPMKLNEVSSIQVARTKTNMEEFN
RVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSTIGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSIRTE
IEKIKPDFLIIDSIQTIMSPDISSVQGSVSQVREVTNELMQIAKTNNIATFIVGHMTKEGTLAGPRTLEHMVDTVLYFEG
ERQHTFRILRAVKNRFGSTNEIGIFEMQSQGLVEVLNPSEVFLEERLDGATGSAIVVTMEGTRPILAEVQALVTPTMFGN
AKRTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVALASSYKDKPTNPQECFIGEIGLTGE
IRRVNRIEQRINEAAKLGFTKVYAPKNSLTGIKVPKEITVISVTTIGEVLQKVFNL

Nucleotide

• Length: 1371 bp

>NTDB_id=145906 AA105_RS10570 WP_004298358.1 2093273..2094643(-) (radA) [Streptococcus suis strain NSUI002]
ATGACCATCGCTAAGAAAAAAACAACCTTTGTCTGTCAATCCTGCGAGTACCACTCGCCCAAGTATCTGGGCCGTTGCCC
CAACTGTGGCTCCTGGTCTAGCTTTGTCGAGGAAGTGGAAGTCGCTGAAGTCAAGAACGAGCGGGTCAGTCTGACAGGTG
AGAAGACCCGTCCTATGAAGCTCAATGAAGTGTCGTCCATTCAAGTGGCCCGCACCAAGACCAATATGGAAGAGTTTAAC
CGTGTCCTTGGTGGCGGCGTGGTGCCGGGCAGTCTGGTCCTGATTGGAGGCGATCCAGGGATTGGCAAATCGACCTTGCT
CCTGCAAGTATCGACCCAACTTTCGACTATTGGCACCGTCCTCTATGTGTCGGGGGAAGAGTCTGCCCAGCAGATTAAGT
TGCGAGCGGAGCGTTTGGGCGACATTGACAGCGAGTTCTATCTCTATGCGGAGACCAATATGCAGAGCATTCGGACTGAG
ATTGAGAAAATCAAGCCAGATTTCCTGATTATCGACTCTATCCAGACCATTATGAGCCCTGACATTTCTAGCGTGCAAGG
TTCTGTCAGTCAGGTCCGTGAAGTGACCAATGAGCTTATGCAGATTGCCAAGACCAACAATATCGCAACCTTTATCGTCG
GCCACATGACCAAGGAAGGCACCCTGGCTGGACCGCGGACCTTGGAGCACATGGTAGACACCGTTCTCTATTTTGAGGGC
GAGCGTCAACACACCTTCCGTATCTTGAGGGCGGTCAAAAATCGCTTTGGCTCCACCAACGAAATCGGTATTTTTGAAAT
GCAGTCGCAGGGCTTGGTCGAAGTTCTCAATCCAAGTGAGGTCTTTCTGGAAGAGCGTCTGGACGGAGCGACTGGCTCGG
CTATTGTCGTGACCATGGAGGGCACCCGCCCTATCCTTGCCGAAGTGCAGGCTCTGGTGACCCCGACCATGTTTGGCAAT
GCCAAGCGGACCACGACAGGCTTGGATTTCAACCGTGCCAGCTTGATTATGGCGGTTTTGGAAAAACGGGCCGGTCTGCT
CCTCCAAAACCAAGATGCCTACCTTAAGTCAGCAGGCGGTGTCAAACTGGATGAGCCAGCTATTGACCTAGCGGTCGCAG
TTGCCCTTGCCTCCAGTTACAAGGACAAGCCAACCAACCCACAAGAGTGCTTTATAGGCGAGATTGGCCTGACAGGGGAA
ATCCGCCGCGTCAATCGGATTGAACAACGGATTAACGAAGCCGCCAAATTGGGCTTTACCAAGGTCTATGCCCCAAAAAA
TTCCCTGACAGGTATCAAGGTGCCCAAGGAAATCACCGTTATCAGCGTGACCACCATTGGCGAAGTCTTGCAGAAAGTAT
TCAACTTATGA

Domains

Predicted by InterproScan.

• Subunit ChlI of Mg-chelatase (ChlI) (363-427)

• Rubredoxin metal binding domain (Zn_ribbon_LapB) (10-37)

• AAA domain (AAA_25) (64-220)

3D structure

• AlphaFold DB: A0A126UJP8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
radA	Streptococcus mitis NCTC 12261	91.15	99.123	0.904
radA	Streptococcus pneumoniae D39	90.929	99.123	0.901
radA	Streptococcus pneumoniae R6	90.929	99.123	0.901
radA	Streptococcus pneumoniae Rx1	90.929	99.123	0.901
radA	Streptococcus pneumoniae TIGR4	90.929	99.123	0.901
radA	Streptococcus mitis SK321	90.708	99.123	0.899
radA	Bacillus subtilis subsp. subtilis str. 168	62.472	99.342	0.621