Detailed information NTG0145898

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AA105_RS08605
• Genome accession: NZ_CP011419
• Coordinates: 1707185..1708234 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain NSUI002
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1702185..1713234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AA105_RS08585 (AA105_08595)	nadE	1703013..1703837 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
AA105_RS08590 (AA105_08600)	-	1704711..1705238 (-)	528	WP_004194600.1	VanZ family protein	-
AA105_RS08595 (AA105_08605)	rlmN	1705235..1706347 (-)	1113	WP_004194597.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
AA105_RS08600 (AA105_08610)	-	1706356..1706997 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
AA105_RS08605 (AA105_08615)	sepM	1707185..1708234 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
AA105_RS08610 (AA105_08620)	coaD	1708221..1708709 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
AA105_RS08615 (AA105_08625)	rsmD	1708699..1709238 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AA105_RS08620 (AA105_08630)	-	1709537..1710259 (-)	723	WP_013730502.1	hypothetical protein	-
AA105_RS08625 (AA105_08635)	-	1710316..1710702 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
AA105_RS08630 (AA105_08640)	-	1710702..1710920 (-)	219	WP_004194736.1	YqgQ family protein	-
AA105_RS08635 (AA105_08645)	-	1711220..1711822 (-)	603	WP_004194738.1	response regulator transcription factor	-
AA105_RS08640 (AA105_08650)	-	1711819..1712913 (-)	1095	WP_024394990.1	histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=145898 AA105_RS08605 WP_009910567.1 1707185..1708234(-) (sepM) [Streptococcus suis strain NSUI002]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=145898 AA105_RS08605 WP_009910567.1 1707185..1708234(-) (sepM) [Streptococcus suis strain NSUI002]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602