Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   SpyM6JRS4_RS08560 Genome accession   NZ_CP011414
Coordinates   1727192..1727905 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes JRS4     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1722192..1732905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SpyM6JRS4_RS08550 (SpyM6JRS4_08545) treC 1723262..1724890 (-) 1629 WP_011185052.1 alpha,alpha-phosphotrehalase -
  SpyM6JRS4_RS08555 (SpyM6JRS4_08550) treP 1724957..1726981 (-) 2025 WP_011185053.1 PTS system trehalose-specific EIIBC component -
  SpyM6JRS4_RS08560 (SpyM6JRS4_08555) treR 1727192..1727905 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  SpyM6JRS4_RS08565 (SpyM6JRS4_08560) - 1728184..1728510 (-) 327 WP_011185054.1 helix-turn-helix domain-containing protein -
  SpyM6JRS4_RS08570 (SpyM6JRS4_08565) - 1728696..1729544 (+) 849 Protein_1657 VOC family protein -
  SpyM6JRS4_RS08575 (SpyM6JRS4_08570) yaaA 1729586..1730317 (+) 732 WP_047149521.1 peroxide stress protein YaaA -
  SpyM6JRS4_RS08580 (SpyM6JRS4_08575) nrdG 1730491..1731105 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  SpyM6JRS4_RS08585 (SpyM6JRS4_08580) - 1731105..1731614 (-) 510 WP_011185058.1 GNAT family N-acetyltransferase -
  SpyM6JRS4_RS08590 (SpyM6JRS4_08585) - 1731623..1732558 (-) 936 WP_002992828.1 Gfo/Idh/MocA family protein -
  SpyM6JRS4_RS09705 - 1732587..1732733 (-) 147 WP_002982210.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=145771 SpyM6JRS4_RS08560 WP_002982243.1 1727192..1727905(+) (treR) [Streptococcus pyogenes JRS4]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=145771 SpyM6JRS4_RS08560 WP_002982243.1 1727192..1727905(+) (treR) [Streptococcus pyogenes JRS4]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment