Detailed information NTG0145765

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: SpyM6JRS4_RS06880
• Genome accession: NZ_CP011414
• Coordinates: 1368246..1368971 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes JRS4
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1363246..1373971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SpyM6JRS4_RS06845 (SpyM6JRS4_06840)	rnpM	1363275..1363571 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
SpyM6JRS4_RS06850 (SpyM6JRS4_06845)	nusA	1363587..1364744 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
SpyM6JRS4_RS06855 (SpyM6JRS4_06850)	rimP	1364919..1365455 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
SpyM6JRS4_RS06865 (SpyM6JRS4_06860)	trmB	1365719..1366354 (-)	636	WP_011184863.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
SpyM6JRS4_RS06870 (SpyM6JRS4_06865)	ccrZ	1366354..1367145 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
SpyM6JRS4_RS06875 (SpyM6JRS4_06870)	-	1367209..1368243 (-)	1035	WP_002983381.1	ABC transporter permease	-
SpyM6JRS4_RS06880 (SpyM6JRS4_06875)	pptA	1368246..1368971 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
SpyM6JRS4_RS06885 (SpyM6JRS4_06880)	-	1369043..1369462 (+)	420	WP_002983376.1	HIT family protein	-
SpyM6JRS4_RS06890 (SpyM6JRS4_06885)	-	1369459..1369815 (+)	357	WP_002988657.1	hypothetical protein	-
SpyM6JRS4_RS06895 (SpyM6JRS4_06890)	brpA	1369926..1371209 (-)	1284	WP_011184864.1	biofilm formation/cell division transcriptional regulator BrpA	-
SpyM6JRS4_RS06900 (SpyM6JRS4_06895)	-	1371218..1371742 (-)	525	WP_011184865.1	GNAT family N-acetyltransferase	-
SpyM6JRS4_RS06905 (SpyM6JRS4_06900)	tsaE	1371717..1372178 (-)	462	WP_011184866.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
SpyM6JRS4_RS06910 (SpyM6JRS4_06905)	-	1372332..1373792 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=145765 SpyM6JRS4_RS06880 WP_002983379.1 1368246..1368971(-) (pptA) [Streptococcus pyogenes JRS4]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=145765 SpyM6JRS4_RS06880 WP_002983379.1 1368246..1368971(-) (pptA) [Streptococcus pyogenes JRS4]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714