Detailed information NTG0145359

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: JEONG1266_RS22960
• Genome accession: NZ_CP014314
• Coordinates: 4463751..4464776 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli O157:H7 strain JEONG-1266
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4458751..4469776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JEONG1266_RS22950 (JEONG1266_22945)	rpmE	4460982..4461194 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
JEONG1266_RS22955 (JEONG1266_22950)	priA	4461397..4463595 (+)	2199	WP_001301674.1	primosomal protein N'	Machinery gene
JEONG1266_RS22960 (JEONG1266_22955)	cytR	4463751..4464776 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
JEONG1266_RS22965 (JEONG1266_22960)	ftsN	4464868..4465827 (+)	960	WP_000068837.1	cell division protein FtsN	-
JEONG1266_RS22970 (JEONG1266_22965)	hslV	4465920..4466450 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
JEONG1266_RS22975 (JEONG1266_22970)	hslU	4466460..4467791 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
JEONG1266_RS22980 (JEONG1266_22975)	menA	4467858..4468784 (+)	927	WP_001308187.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
JEONG1266_RS22985 (JEONG1266_22980)	rraA	4468877..4469362 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=145359 JEONG1266_RS22960 WP_000644904.1 4463751..4464776(+) (cytR) [Escherichia coli O157:H7 strain JEONG-1266]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=145359 JEONG1266_RS22960 WP_000644904.1 4463751..4464776(+) (cytR) [Escherichia coli O157:H7 strain JEONG-1266]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAAGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGTGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628