Detailed information NTG0144442

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: AWB63_RS08170
• Genome accession: NZ_CP014144
• Coordinates: 1793036..1795141 (+)
• Length: 701 a.a.
• NCBI ID: WP_038676649.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain JF
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1788036..1800141

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AWB63_RS08140 (AWB63_08140)	yhbY	1788125..1788442 (+)	318	WP_002884193.1	ribosome assembly RNA-binding protein YhbY	-
AWB63_RS08145 (AWB63_08145)	-	1788550..1789182 (+)	633	WP_002884372.1	nicotinate-nucleotide adenylyltransferase	-
AWB63_RS08150 (AWB63_08150)	yqeK	1789179..1789769 (+)	591	WP_038676655.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
AWB63_RS08155 (AWB63_08155)	rsfS	1789793..1790146 (+)	354	WP_014632696.1	ribosome silencing factor	-
AWB63_RS08160 (AWB63_08160)	-	1790465..1791205 (+)	741	WP_013991077.1	class I SAM-dependent DNA methyltransferase	-
AWB63_RS08165 (AWB63_08165)	-	1791212..1792303 (+)	1092	WP_038676651.1	nucleotidyltransferase	-
AWB63_RS08170 (AWB63_08170)	clpE	1793036..1795141 (+)	2106	WP_038676649.1	AAA family ATPase	Regulator
AWB63_RS10895	-	1795577..1795702 (+)	126	WP_002884447.1	hypothetical protein	-
AWB63_RS08175 (AWB63_08175)	-	1795720..1796328 (+)	609	WP_002884297.1	DUF4230 domain-containing protein	-
AWB63_RS10740 (AWB63_08180)	-	1796422..1796886 (+)	465	WP_172855709.1	hypothetical protein	-
AWB63_RS10745	-	1796904..1797071 (+)	168	WP_002884708.1	hypothetical protein	-
AWB63_RS08185 (AWB63_08185)	-	1797251..1797550 (-)	300	WP_002884229.1	hypothetical protein	-
AWB63_RS08190 (AWB63_08190)	-	1797547..1797966 (-)	420	WP_002891660.1	HIT family protein	-
AWB63_RS08195 (AWB63_08195)	pptA	1798031..1798762 (+)	732	WP_038676648.1	ABC transporter ATP-binding protein	Regulator
AWB63_RS08200 (AWB63_08200)	pptB	1798759..1799796 (+)	1038	WP_038676646.1	ABC transporter permease	Regulator

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77347.30 Da
• Isoelectric Point: 4.7718

>NTDB_id=144442 AWB63_RS08170 WP_038676649.1 1793036..1795141(+) (clpE) [Streptococcus salivarius strain JF]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQHQGKGPKQDGIIAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGILVIKEKDAK

Nucleotide

• Length: 2106 bp

>NTDB_id=144442 AWB63_RS08170 WP_038676649.1 1793036..1795141(+) (clpE) [Streptococcus salivarius strain JF]
ATGAACAACAACTTTAACAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATTATTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGGGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAATAAAGAAATCATTTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAAGATGAATATCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACTTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAGGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCGCAAATGGGAGCAACTGAT
ATCGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACTAAAGATGCTATTATCCGTTTGGACATGTCA
GAATATAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTTCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATTGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGCTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTATCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (441-601)

• AAA lid domain (AAA_lid_9) (257-351)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (608-678)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.505	100	0.465
clpC	Lactococcus lactis subsp. cremoris KW2	48.848	92.867	0.454
clpE	Streptococcus pneumoniae Rx1	48.523	91.726	0.445
clpE	Streptococcus pneumoniae TIGR4	48.523	91.726	0.445
clpE	Streptococcus pneumoniae R6	48.523	91.726	0.445
clpE	Streptococcus pneumoniae D39	48.523	91.726	0.445
clpC	Bacillus subtilis subsp. subtilis str. 168	45.723	91.726	0.419
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.089	92.867	0.391
clpC	Streptococcus thermophilus LMD-9	43.274	88.017	0.381
clpC	Streptococcus pneumoniae Rx1	43.322	87.589	0.379
clpC	Streptococcus pneumoniae D39	43.322	87.589	0.379
clpC	Streptococcus pneumoniae TIGR4	43.322	87.589	0.379
clpC	Streptococcus thermophilus LMG 18311	42.811	88.302	0.378
clpC	Streptococcus mutans UA159	42.173	89.301	0.377