Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   AV644_RS09685 Genome accession   NZ_CP013908
Coordinates   1876966..1878300 (-) Length   444 a.a.
NCBI ID   WP_001089366.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS-M002     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1871966..1883300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AV644_RS09650 (AV644_09370) - 1872239..1872664 (-) 426 WP_000823126.1 PTS mannose transporter subunit IIA -
  AV644_RS09655 (AV644_09375) - 1872911..1873945 (-) 1035 Protein_1793 acyltransferase family protein -
  AV644_RS11200 - 1873997..1874179 (+) 183 WP_001866975.1 hypothetical protein -
  AV644_RS09665 (AV644_09380) - 1874174..1875328 (-) 1155 WP_000623428.1 ABC transporter permease subunit -
  AV644_RS09670 (AV644_09385) - 1875334..1876182 (-) 849 WP_000926590.1 ABC transporter ATP-binding protein -
  AV644_RS09675 - 1876251..1876424 (-) 174 WP_000683600.1 hypothetical protein -
  AV644_RS09680 (AV644_09390) - 1876713..1876877 (+) 165 Protein_1798 cysteine peptidase family C39 domain-containing protein -
  AV644_RS09685 (AV644_09395) comD/blpH 1876966..1878300 (-) 1335 WP_001089366.1 sensor histidine kinase Regulator
  AV644_RS09690 (AV644_09400) comE/blpR 1878297..1879049 (-) 753 WP_001019938.1 response regulator transcription factor Regulator
  AV644_RS09700 (AV644_09405) - 1879265..1880080 (-) 816 WP_001029870.1 endonuclease/exonuclease/phosphatase family protein -
  AV644_RS09705 (AV644_09410) - 1880134..1882317 (-) 2184 WP_000795065.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 444 a.a.        Molecular weight: 51244.98 Da        Isoelectric Point: 8.0286

>NTDB_id=143085 AV644_RS09685 WP_001089366.1 1876966..1878300(-) (comD/blpH) [Streptococcus agalactiae strain GBS-M002]
MNSTLSILEIALTIILTIFLFSKISGRQLTLIEIGICIALRLGLVILFIAANTIINLSFLKYWLLPIYMLSLAFLLLRPI
SKTLVVFYGLFPIVLRNLCSRSLAFFVFPLFNIDFHTTNQGFWGYFVDVLSTLCVLLFLRWMQYDFKTLRSSEVSPIDKR
ILQFTNGCMVSYYLLMQFSTYLEYELAINTVIYRQFLLVVYWIIFTGAIASLDRRLRNSLQERLAVQRELQLANMIDYSH
HIEGLYKEVRSFRHDYSNMLTTLKLGIDNEDISIVKSVYQSIFKESNTHFRHPKYNIDRLVNVDNPALKSLLAAKLSQAI
DNHIMVSIEVPDSIKPQGMELIDFITIVSVLWDNAIEASLETDDPKIAMSYFTLKHKQIFIIENSTKENAIDTSTIFNYE
ISSKGRNRGIGLYNVRGVINRYPNISIATSSQDFSFCQTFEIIL

Nucleotide


Download         Length: 1335 bp        

>NTDB_id=143085 AV644_RS09685 WP_001089366.1 1876966..1878300(-) (comD/blpH) [Streptococcus agalactiae strain GBS-M002]
ATGAATTCTACTCTATCCATCTTAGAGATAGCTTTAACGATAATATTAACAATATTTCTCTTTTCTAAAATCAGTGGACG
TCAATTGACTTTAATAGAGATTGGAATTTGTATTGCTCTGAGATTAGGACTTGTAATTTTATTTATAGCAGCTAATACTA
TTATTAATCTTTCATTTCTAAAGTACTGGCTTCTCCCCATCTATATGTTAAGTCTGGCTTTCTTGTTGCTAAGACCTATA
TCTAAAACTTTAGTAGTCTTTTATGGCTTGTTTCCAATTGTTCTCAGAAATCTTTGTTCACGTTCTTTAGCTTTTTTTGT
CTTTCCTTTGTTTAATATTGATTTTCATACAACCAACCAGGGGTTTTGGGGATATTTTGTTGATGTCTTGTCTACTCTTT
GTGTTCTCCTATTTTTAAGATGGATGCAATACGACTTTAAAACTTTGCGAAGTAGTGAAGTTTCGCCCATAGATAAGAGA
ATTCTCCAATTTACGAATGGTTGTATGGTCAGTTATTACTTACTGATGCAGTTTTCAACTTATTTGGAATATGAATTAGC
CATCAATACTGTTATTTACCGGCAATTTTTGCTTGTTGTTTATTGGATTATATTTACGGGAGCAATAGCCAGTTTAGACC
GGAGACTTCGAAATTCTTTACAGGAGAGGTTAGCTGTTCAAAGAGAACTCCAATTGGCTAATATGATAGATTATAGCCAC
CATATTGAGGGGTTGTATAAAGAAGTTAGGAGCTTCCGACATGATTATAGTAACATGTTAACGACCTTGAAACTAGGGAT
TGATAATGAAGATATATCTATTGTCAAATCAGTTTATCAGTCTATCTTTAAAGAATCTAATACACATTTCCGACATCCTA
AGTATAATATAGACCGGTTGGTTAATGTAGATAACCCAGCCTTAAAAAGTCTTTTAGCAGCCAAGCTTTCACAAGCGATA
GACAATCATATTATGGTATCTATAGAAGTACCAGACAGTATTAAACCTCAAGGGATGGAACTGATTGATTTTATTACCAT
TGTATCTGTTTTATGGGATAACGCTATTGAGGCTTCTTTAGAGACAGACGATCCTAAGATAGCCATGTCTTATTTTACAT
TAAAACATAAACAAATTTTTATCATAGAAAATTCAACTAAGGAAAATGCAATAGATACGTCAACGATATTCAATTATGAG
ATAAGTAGTAAGGGGCGGAATAGAGGAATAGGTCTTTACAATGTCAGGGGAGTTATCAATCGTTATCCAAATATTTCTAT
TGCAACAAGTAGCCAAGATTTTAGTTTCTGCCAAACTTTCGAAATCATATTATAG

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(339-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

35.683

100

0.365