Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   MOVS_RS04760 Genome accession   NZ_CP011158
Coordinates   987436..988371 (+) Length   311 a.a.
NCBI ID   WP_036362363.1    Uniprot ID   A0A378PKS0
Organism   Moraxella ovis strain 199/55     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 987436..1016755 987436..988371 within 0


Gene organization within MGE regions


Location: 987436..1016755
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MOVS_RS04760 (MOVS_04690) pilA 987436..988371 (+) 936 WP_036362363.1 signal recognition particle-docking protein FtsY Machinery gene
  MOVS_RS04765 (MOVS_04695) - 988425..988967 (+) 543 WP_063513967.1 methylated-DNA--[protein]-cysteine S-methyltransferase -
  MOVS_RS04770 (MOVS_04700) - 989109..990134 (+) 1026 WP_063513968.1 quinone-dependent dihydroorotate dehydrogenase -
  MOVS_RS04775 (MOVS_04705) - 990134..990664 (+) 531 WP_063513969.1 CvpA family protein -
  MOVS_RS04780 (MOVS_04710) purF 990681..992201 (+) 1521 WP_063513970.1 amidophosphoribosyltransferase -
  MOVS_RS04785 (MOVS_04715) - 992367..993671 (+) 1305 WP_407662074.1 lytic murein transglycosylase -
  MOVS_RS04790 (MOVS_04720) - 993737..994657 (-) 921 WP_063513972.1 transaldolase -
  MOVS_RS04795 (MOVS_04725) pheA 994881..995990 (+) 1110 WP_063513973.1 prephenate dehydratase -
  MOVS_RS04800 (MOVS_04730) - 996060..998372 (+) 2313 WP_063513974.1 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase -
  MOVS_RS04805 (MOVS_04735) rarD 998372..999259 (+) 888 WP_063513975.1 EamA family transporter RarD -
  MOVS_RS04810 (MOVS_04740) folB 999279..999632 (+) 354 WP_063513976.1 dihydroneopterin aldolase -
  MOVS_RS04815 (MOVS_04745) - 999650..1000069 (+) 420 WP_167541389.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  MOVS_RS04820 (MOVS_04750) - 1000231..1002087 (-) 1857 WP_063513977.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -
  MOVS_RS04825 - 1002214..1002735 (-) 522 WP_063513978.1 hypothetical protein -
  MOVS_RS04830 - 1002735..1003760 (-) 1026 WP_063513979.1 hypothetical protein -
  MOVS_RS04835 (MOVS_04765) - 1003884..1004255 (-) 372 WP_063513980.1 hypothetical protein -
  MOVS_RS11720 - 1004257..1004754 (-) 498 WP_218563643.1 hypothetical protein -
  MOVS_RS04845 (MOVS_04775) - 1004938..1009878 (-) 4941 WP_063513981.1 hemagglutinin repeat-containing protein -
  MOVS_RS04850 - 1010330..1012609 (-) 2280 WP_063513982.1 filamentous hemagglutinin N-terminal domain-containing protein -
  MOVS_RS11390 - 1012699..1013718 (+) 1020 WP_228703601.1 ribonuclease domain-containing protein -
  MOVS_RS04860 (MOVS_04795) - 1013715..1014008 (+) 294 WP_063513983.1 barstar family protein -
  MOVS_RS04865 (MOVS_04800) - 1014082..1014390 (+) 309 WP_063513984.1 hypothetical protein -
  MOVS_RS04870 (MOVS_04805) - 1014375..1015148 (-) 774 WP_063513985.1 helix-turn-helix transcriptional regulator -
  MOVS_RS04875 (MOVS_04810) istA 1015163..1016755 (+) 1593 WP_063513986.1 IS21 family transposase -

Sequence

Protein


Download         Length: 311 a.a.        Molecular weight: 33694.48 Da        Isoelectric Point: 4.8063

>NTDB_id=143022 MOVS_RS04760 WP_036362363.1 987436..988371(+) (pilA) [Moraxella ovis strain 199/55]
MSENQGWFSRMKQGLSKSSKNLTEGLMNVLVGGKEIDDELLEEVEDQLLVADIGVDATNRIIKSLTEQTARGDLIYSHSL
YKALKKELVEILEPKVHPLQIDTSKKPFVILMVGVNGVGKTTTIGKLAKRLQGEGKSVMLAAGDTFRAAATEQLQIWGER
NGIPVVAQGHGADSASVIFDAMQSARAKGIDVLIADTAGRLQNKIHLMNELEKVVRVMKKADETAPHETMIVLDAGTGQN
AINQVQIFGEATPLSGITITKLDGTAKGGVVFNVAQNTDVPIRYIGVGERIDDLQAFDPNDFVDALFDEEQ

Nucleotide


Download         Length: 936 bp        

>NTDB_id=143022 MOVS_RS04760 WP_036362363.1 987436..988371(+) (pilA) [Moraxella ovis strain 199/55]
ATGAGCGAAAATCAAGGCTGGTTTAGCCGAATGAAACAAGGACTGTCTAAGTCTAGCAAAAACCTAACCGAAGGGCTGAT
GAATGTTCTGGTTGGGGGCAAGGAGATTGATGACGAGCTGCTGGAGGAAGTCGAGGATCAGCTCTTGGTGGCGGATATTG
GTGTTGATGCCACGAATCGCATCATCAAGAGCTTAACCGAGCAGACGGCGCGTGGCGATTTGATCTATTCGCATTCATTA
TATAAAGCCCTAAAAAAAGAGCTGGTCGAGATTCTAGAGCCTAAAGTTCATCCTCTACAGATCGACACGTCAAAAAAACC
ATTCGTCATTCTCATGGTAGGCGTTAATGGTGTGGGCAAGACGACCACCATTGGCAAGCTCGCCAAGCGACTACAGGGCG
AGGGTAAGTCGGTGATGCTCGCAGCGGGGGACACTTTCCGCGCTGCTGCAACCGAGCAGCTGCAGATCTGGGGCGAGCGT
AATGGCATTCCTGTGGTTGCCCAAGGACATGGTGCTGACAGTGCTTCGGTCATCTTTGATGCCATGCAGTCAGCGCGCGC
CAAAGGCATTGATGTGCTGATCGCAGATACAGCAGGACGCCTGCAGAATAAGATACATCTGATGAACGAACTAGAGAAAG
TCGTACGCGTCATGAAGAAGGCAGATGAGACGGCGCCGCATGAGACGATGATCGTTCTAGATGCTGGCACAGGTCAAAAC
GCCATCAACCAAGTTCAGATATTTGGTGAGGCGACGCCATTGTCAGGCATTACCATCACTAAGCTAGACGGCACCGCCAA
AGGGGGTGTGGTCTTTAACGTTGCTCAGAATACCGATGTGCCGATTCGCTATATTGGCGTGGGCGAGCGCATTGATGATT
TGCAGGCATTTGATCCTAATGATTTTGTCGATGCGCTGTTTGATGAAGAGCAATAA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(22-88)

SRP54-type protein, GTPase domain (SRP54)

(107-307)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A378PKS0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

52.475

97.428

0.511

Multiple sequence alignment