Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   MGAS27061_RS07975 Genome accession   NZ_CP013840
Coordinates   1659760..1660473 (+) Length   237 a.a.
NCBI ID   WP_002992823.1    Uniprot ID   A0A0H2UWR7
Organism   Streptococcus pyogenes strain MGAS27061     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1654760..1665473
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS27061_RS07965 (MGAS27061_1633) treC 1655829..1657457 (-) 1629 WP_023079166.1 alpha,alpha-phosphotrehalase -
  MGAS27061_RS07970 (MGAS27061_1634) treP 1657525..1659549 (-) 2025 WP_031488635.1 PTS system trehalose-specific EIIBC component -
  MGAS27061_RS07975 (MGAS27061_1635) treR 1659760..1660473 (+) 714 WP_002992823.1 trehalose operon repressor Regulator
  MGAS27061_RS07980 (MGAS27061_1637) - 1660752..1661083 (-) 332 Protein_1542 winged helix-turn-helix transcriptional regulator -
  MGAS27061_RS07985 (MGAS27061_1638) - 1661262..1662395 (-) 1134 WP_014407456.1 ISAs1-like element IS1548 family transposase -
  MGAS27061_RS07990 (MGAS27061_1639) - 1662596..1663453 (+) 858 WP_031488768.1 VOC family protein -
  MGAS27061_RS07995 (MGAS27061_1640) yaaA 1663495..1664226 (+) 732 WP_031488767.1 peroxide stress protein YaaA -
  MGAS27061_RS08000 (MGAS27061_1641) nrdG 1664400..1665014 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27620.79 Da        Isoelectric Point: 9.6307

>NTDB_id=142986 MGAS27061_RS07975 WP_002992823.1 1659760..1660473(+) (treR) [Streptococcus pyogenes strain MGAS27061]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIRHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=142986 MGAS27061_RS07975 WP_002992823.1 1659760..1660473(+) (treR) [Streptococcus pyogenes strain MGAS27061]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAGACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTCTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UWR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.376

98.734

0.675

Multiple sequence alignment