Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   MGAS23530_RS03550 Genome accession   NZ_CP013839
Coordinates   717329..717805 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain MGAS23530     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 712329..722805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS23530_RS03525 (MGAS23530_0733) - 712370..713158 (+) 789 WP_031488333.1 Nif3-like dinuclear metal center hexameric protein -
  MGAS23530_RS03530 (MGAS23530_0734) - 713198..714304 (+) 1107 WP_031488332.1 NAD(P)/FAD-dependent oxidoreductase -
  MGAS23530_RS03535 (MGAS23530_0735) rfbA 714362..715231 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  MGAS23530_RS03540 (MGAS23530_0736) - 715231..715824 (+) 594 WP_031488331.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  MGAS23530_RS03545 (MGAS23530_0737) rfbB 716068..717108 (+) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  MGAS23530_RS03550 (MGAS23530_0738) mutX 717329..717805 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  MGAS23530_RS03555 (MGAS23530_0739) - 717863..719044 (+) 1182 WP_031488330.1 AI-2E family transporter -
  MGAS23530_RS03560 (MGAS23530_0740) - 719034..720281 (+) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  MGAS23530_RS03565 (MGAS23530_0741) fbp54 720340..721992 (-) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=142855 MGAS23530_RS03550 WP_002984880.1 717329..717805(+) (mutX) [Streptococcus pyogenes strain MGAS23530]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=142855 MGAS23530_RS03550 WP_002984880.1 717329..717805(+) (mutX) [Streptococcus pyogenes strain MGAS23530]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703