Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AS200_RS11210 Genome accession   NZ_CP013743
Coordinates   2549034..2549708 (-) Length   224 a.a.
NCBI ID   WP_058922235.1    Uniprot ID   -
Organism   Streptomyces sp. CdTB01     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2544034..2554708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AS200_RS11190 (AS200_11190) - 2544506..2545654 (-) 1149 WP_058922231.1 ROK family glucokinase -
  AS200_RS11195 (AS200_11195) - 2545826..2546563 (-) 738 WP_203237823.1 GntR family transcriptional regulator -
  AS200_RS11200 (AS200_11200) - 2546693..2547715 (+) 1023 WP_058922233.1 Gfo/Idh/MocA family oxidoreductase -
  AS200_RS11205 (AS200_11205) - 2547777..2548961 (-) 1185 WP_058922234.1 cytochrome P450 -
  AS200_RS11210 (AS200_11210) vraR 2549034..2549708 (-) 675 WP_058922235.1 response regulator transcription factor Regulator
  AS200_RS11215 (AS200_11215) - 2549864..2551120 (-) 1257 WP_058922236.1 histidine kinase -
  AS200_RS11220 (AS200_11220) - 2551289..2551489 (+) 201 WP_058922237.1 hypothetical protein -
  AS200_RS11225 (AS200_11225) - 2551538..2551924 (-) 387 WP_058928067.1 ribonuclease domain-containing protein -
  AS200_RS11230 (AS200_11230) - 2552057..2552683 (-) 627 WP_058922238.1 dihydrofolate reductase family protein -
  AS200_RS11235 (AS200_11235) - 2552765..2553577 (-) 813 WP_079077871.1 AIM24 family protein -
  AS200_RS11240 (AS200_11240) - 2553682..2554440 (+) 759 WP_058922239.1 SDR family oxidoreductase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 23993.44 Da        Isoelectric Point: 4.8725

>NTDB_id=142387 AS200_RS11210 WP_058922235.1 2549034..2549708(-) (vraR) [Streptomyces sp. CdTB01]
MTAIRLLLVDDDPLVRAGLSLMMGGADDIEIVGEAADGGEAEALVDRTRPDVVLMDIRMPSVDGLTATERLRARKDAPQV
VVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVDAVRRVATGDPVLSPTVTRQLVEHAVGNSADTRRARARERVALLND
REREVAVAVGRGLSNAEIAADLFMSVATVKTHVSRVLAKLDLNNRVQIALLAYDAGLLEEPDGH

Nucleotide


Download         Length: 675 bp        

>NTDB_id=142387 AS200_RS11210 WP_058922235.1 2549034..2549708(-) (vraR) [Streptomyces sp. CdTB01]
ATGACTGCGATCAGACTGCTCCTCGTCGACGACGACCCCCTGGTGCGGGCCGGCCTGTCACTGATGATGGGCGGTGCGGA
CGACATCGAGATCGTCGGCGAGGCCGCCGACGGCGGCGAGGCCGAGGCGCTCGTCGACCGGACCCGGCCCGACGTCGTCC
TCATGGACATCCGGATGCCGTCGGTGGACGGTCTCACGGCCACGGAGCGGCTGCGCGCCCGCAAGGACGCCCCGCAGGTC
GTCGTCCTGACCACCTTCCACGCCGACGAGCAGGTCCTGCGCGCCCTGCGCGCGGGGGCCGCCGGGTTCGTCCTCAAGGA
CACCCCGCCCGCCGAGATCGTCGACGCCGTGCGCCGGGTCGCGACCGGCGATCCCGTGCTGTCGCCCACCGTCACCCGCC
AGCTGGTGGAGCACGCCGTGGGCAACTCCGCCGACACGCGCCGGGCACGCGCGCGGGAACGCGTCGCGCTGCTCAACGAC
CGCGAGCGCGAGGTCGCCGTCGCCGTCGGCCGGGGGCTGTCCAACGCGGAGATCGCCGCGGACCTCTTCATGAGCGTCGC
CACCGTCAAGACCCACGTCTCGCGCGTCCTCGCCAAACTGGACCTCAACAACCGGGTGCAGATCGCTTTGTTGGCCTACG
ACGCCGGACTCCTGGAGGAACCGGACGGGCACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(157-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.462

98.661

0.379