Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsA   Type   Regulator
Locus tag   AVR58_RS14110 Genome accession   NZ_CP013742
Coordinates   3091067..3092317 (+) Length   416 a.a.
NCBI ID   WP_010948429.1    Uniprot ID   Q5ZRZ0
Organism   Legionella pneumophila strain Philadelphia-1 isolate AE     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 3086067..3097317
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AVR58_RS14075 (AVR58_13705) - 3086378..3086677 (-) 300 WP_010948422.1 ArsR/SmtB family transcription factor -
  AVR58_RS14080 (AVR58_13710) - 3086930..3087274 (-) 345 WP_010948423.1 hypothetical protein -
  AVR58_RS14085 (AVR58_13715) - 3087391..3088020 (+) 630 WP_010948424.1 trimeric intracellular cation channel family protein -
  AVR58_RS14090 (AVR58_13720) - 3088228..3088722 (-) 495 WP_010948425.1 peptidylprolyl isomerase -
  AVR58_RS14095 (AVR58_13725) tgt 3088749..3089900 (-) 1152 WP_014842761.1 tRNA guanosine(34) transglycosylase Tgt -
  AVR58_RS14100 (AVR58_13730) - 3089962..3090453 (-) 492 WP_016357035.1 disulfide bond formation protein B -
  AVR58_RS14105 (AVR58_13735) - 3090450..3090878 (-) 429 WP_014842763.1 c-type cytochrome -
  AVR58_RS14110 (AVR58_13740) cqsA 3091067..3092317 (+) 1251 WP_010948429.1 quorum-sensing autoinducer LAI-1 synthase LqsA Regulator
  AVR58_RS14115 (AVR58_13745) - 3092399..3093424 (-) 1026 WP_010948430.1 response regulator -
  AVR58_RS14120 (AVR58_13750) - 3093706..3094269 (+) 564 WP_010948431.1 HdeD family acid-resistance protein -
  AVR58_RS14125 (AVR58_13755) - 3094357..3095646 (-) 1290 WP_010948432.1 sensor histidine kinase -
  AVR58_RS14130 (AVR58_13760) hemC 3096038..3096967 (+) 930 WP_027223811.1 hydroxymethylbilane synthase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 46124.69 Da        Isoelectric Point: 9.2711

>NTDB_id=142365 AVR58_RS14110 WP_010948429.1 3091067..3092317(+) (cqsA) [Legionella pneumophila strain Philadelphia-1 isolate AE]
MSNTEYQTIDNKTQYINGKEKHQNHAYPEYINHSMEKYYEGRVNKSWQGKHILKGKTPTANSLIFSSNDYLNISQHPQLI
KAQIAAMQKYGNGQMQSAVFLNNSSFLLSQCEKKFSSFLNYSAALLTQSGWSANVGLIQTLAKYNTPVYLDFYAHMSFWS
GVKAARAKSIPFLHNSVDSLKKRIEHHGPGIIAVDSIYSTLGTISPLADYADIARKFKCLLIVDESHSLGTHGSQGKGMV
AKLGLSSQIDIITASLAKALSGRGGIITGDRQLIEYIRYSSLPSIFSSALMPHDLAGFSASLEIITQEEWRRAKLQTNAD
FLREALSCEGINIGSSGSQIVPLVTGSEANTLWLRDELEKEDIFGAVFCSPATPKNKCLIRLSISAHHEKSDLLRVIECL
VRLARKRPDIPLFKGN

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=142365 AVR58_RS14110 WP_010948429.1 3091067..3092317(+) (cqsA) [Legionella pneumophila strain Philadelphia-1 isolate AE]
ATGAGCAATACAGAATACCAAACAATTGATAACAAGACTCAATATATCAATGGAAAAGAAAAACATCAAAACCATGCTTA
TCCTGAGTACATCAATCATTCCATGGAAAAATATTACGAGGGACGAGTCAATAAATCCTGGCAAGGGAAACACATACTTA
AAGGCAAAACCCCGACTGCAAATTCACTGATTTTTTCGAGCAATGATTATTTAAACATCAGTCAACATCCGCAATTAATT
AAAGCGCAAATTGCTGCGATGCAAAAATATGGTAATGGTCAAATGCAATCTGCTGTATTTTTAAATAACAGCTCTTTTTT
GCTCAGCCAATGTGAAAAGAAATTCAGTTCCTTTTTAAATTATTCTGCGGCCCTGCTCACTCAATCAGGCTGGAGCGCTA
ACGTTGGTCTCATACAAACCCTGGCCAAGTACAATACACCAGTGTATCTGGATTTTTATGCCCATATGTCTTTTTGGTCT
GGTGTAAAAGCAGCAAGAGCCAAATCTATACCGTTTCTACATAATTCAGTCGATTCACTAAAAAAACGAATTGAGCACCA
TGGGCCAGGAATAATTGCAGTAGATTCTATTTATAGTACGCTGGGTACGATTAGTCCATTGGCTGACTATGCTGACATTG
CAAGAAAATTCAAATGTTTGCTCATCGTCGATGAATCTCATTCATTAGGTACGCATGGTTCGCAAGGCAAGGGGATGGTG
GCTAAACTGGGATTATCAAGCCAAATAGACATCATAACAGCAAGCCTGGCTAAAGCCTTATCAGGACGGGGAGGCATCAT
TACAGGAGATAGGCAACTTATAGAATATATCAGATATTCATCTCTACCCTCTATTTTTAGTTCTGCTTTAATGCCTCATG
ATTTAGCAGGATTTAGCGCATCATTAGAAATTATTACTCAAGAAGAATGGAGAAGAGCAAAATTACAAACCAATGCTGAT
TTTTTACGAGAAGCCTTATCATGCGAAGGAATTAATATAGGAAGTAGTGGCTCTCAAATAGTCCCTTTAGTTACAGGCAG
CGAGGCTAACACGCTTTGGTTAAGGGATGAGCTAGAAAAAGAAGACATCTTTGGAGCCGTGTTCTGTTCACCCGCCACTC
CCAAAAATAAATGCCTGATTCGTTTATCCATCAGCGCGCATCACGAAAAATCGGACTTGCTCAGAGTGATTGAGTGCCTG
GTCAGACTTGCAAGAAAAAGACCCGATATTCCTTTGTTTAAGGGTAATTAA

Domains

Predicted by InterProScan.

Aminotransferase class I and II (Aminotran_1_2)

(63-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5ZRZ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsA Vibrio cholerae strain A1552

45.43

89.423

0.406