Detailed information NTG0142089

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AU380_RS20890
• Genome accession: NZ_CP013696
• Coordinates: 4550276..4552825 (-)
• Length: 849 a.a.
• NCBI ID: WP_003114516.1
• Uniprot ID: Q9I1A8
• Organism: Pseudomonas aeruginosa strain 12-4-4(59)
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4545276..4557825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AU380_RS20865 (AU380_20865)	-	4545480..4545875 (+)	396	WP_003089513.1	DUF4280 domain-containing protein	-
AU380_RS20870 (AU380_20870)	-	4545898..4546434 (-)	537	WP_003114514.1	toxin-antitoxin system YwqK family antitoxin	-
AU380_RS20875 (AU380_20875)	tssI	4546445..4548448 (-)	2004	WP_058836815.1	type VI secretion system tip protein VgrG	-
AU380_RS20880 (AU380_20880)	-	4548455..4549240 (-)	786	WP_003116945.1	hypothetical protein	-
AU380_RS20885 (AU380_20885)	-	4549310..4550185 (-)	876	WP_003116944.1	hypothetical protein	-
AU380_RS20890 (AU380_20890)	clpC	4550276..4552825 (-)	2550	WP_003114516.1	type VI secretion system ATPase TssH	Regulator
AU380_RS20895 (AU380_20895)	tssG	4552827..4553843 (-)	1017	WP_023129803.1	type VI secretion system baseplate subunit TssG	-
AU380_RS20900 (AU380_20900)	tssF	4553807..4555600 (-)	1794	WP_058150001.1	type VI secretion system baseplate subunit TssF	-
AU380_RS20905 (AU380_20905)	tssE	4555584..4556009 (-)	426	WP_003122696.1	type VI secretion system baseplate subunit TssE	-
AU380_RS20910 (AU380_20910)	-	4556022..4556519 (-)	498	WP_003089495.1	Hcp family type VI secretion system effector	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 92424.76 Da
• Isoelectric Point: 5.1045

>NTDB_id=142089 AU380_RS20890 WP_003114516.1 4550276..4552825(-) (clpC) [Pseudomonas aeruginosa strain 12-4-4(59)]
MELAALIGRLNPDCRRALERAAQRCLQRTHHYVEIEHLLLELLDIDGGDFACLLPRFGLERDALVAEINLSLELFKAGNT
RTPALSAHTIGLLEDAVVHASVLGQAQIRSGLLLLALLDREERRALLLNSASSLLRIPHEALQANLLEWIQASREQPPAP
NRPAAGGDKPESAPDPLLDQYTQDLTAEARAGRIDPIVGRDGEIRQCVDILLRRRQNNPILVGAPGVGKTAVVEGLALRI
AAGEVPPSLQEVILRVLDLGLLQAGASMKGEFEQRLKGVIDAVRNSAQPIILFIDEAHTLIGAGGAEGGSDAANLLKPAL
ARGELRTLAATTWLEYKKYFEKDPALTRRFQLVQVEEPDEATAVEMLRGVAGKLELHHGVQIMDAAIVDAVKLSHRYISG
RQLPDKAISVLDTACARVALGQHDVPPPLESLRHREQALEEELQRLRREQATGLDHSARITALESESGDNRRTIRELETR
WDEEREAVRELLDIRRELLALSESADAAKPDEELDGRIDHLAAELARLAAGLEAIRQDDPLVPEQVDSRTVAAVIAGWTG
IPVGKMLADEAHAIRSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLPGPTGVGKTETAYALADALYGG
ERNLISINLSEYQEAHTVSQLKGAPPGYVGYGSGGVLTEAVRRKPYSVVLLDEIEKAHPDVLEAFYNVFDKGVMEDGTGL
VVDFRNTVILATSNVGAELLLDSPAEQVATPAFDERLRKVLLQTFRPAFLARMTVVPYRPLEEATLEGIVVAKLEKLRER
YKAATGKQFDFDPAIVKAVLAKCSAAGARDIENVLMAQVTGKLAEWVLE

Nucleotide

• Length: 2550 bp

>NTDB_id=142089 AU380_RS20890 WP_003114516.1 4550276..4552825(-) (clpC) [Pseudomonas aeruginosa strain 12-4-4(59)]
ATGGAACTCGCCGCCCTGATCGGCCGCCTCAACCCGGACTGTCGCCGCGCCCTGGAGCGCGCCGCGCAACGCTGCCTGCA
ACGCACCCATCATTACGTAGAGATCGAGCACCTGCTGCTGGAGCTGCTGGACATCGACGGCGGCGACTTCGCCTGCCTGC
TGCCGCGCTTCGGCCTGGAGCGCGACGCCCTGGTCGCCGAGATCAACCTGTCGCTGGAGCTGTTCAAGGCCGGCAATACC
CGCACTCCGGCGCTGTCCGCGCACACCATCGGCCTGCTCGAAGACGCCGTGGTCCACGCCAGCGTGCTCGGCCAGGCGCA
GATCCGTTCCGGCCTGCTGCTGCTCGCCCTGCTCGACCGCGAGGAGCGCCGCGCCCTGCTGCTGAACAGCGCGTCGTCGC
TACTGCGGATTCCCCACGAGGCCTTGCAGGCCAACCTGCTGGAGTGGATCCAGGCCTCCCGCGAACAGCCGCCCGCGCCG
AACCGCCCGGCGGCAGGCGGCGACAAGCCGGAAAGCGCCCCGGACCCGCTGCTCGACCAGTACACCCAGGACCTCACCGC
CGAAGCCCGCGCCGGGCGCATCGACCCCATAGTCGGGCGCGACGGGGAGATCCGCCAGTGCGTCGACATCCTCCTGCGCC
GGCGGCAGAACAACCCGATCCTGGTCGGCGCGCCGGGCGTCGGCAAGACCGCGGTGGTCGAGGGCCTGGCCCTGCGCATC
GCCGCCGGCGAGGTGCCGCCGTCGTTGCAGGAGGTGATCCTGCGGGTGCTCGACCTCGGCCTGTTGCAGGCCGGCGCCAG
CATGAAGGGCGAGTTCGAGCAGCGCCTCAAGGGCGTGATCGACGCCGTGCGCAACAGCGCGCAGCCGATCATCCTGTTCA
TCGACGAGGCGCACACGCTGATCGGCGCCGGCGGCGCGGAAGGCGGCAGCGACGCCGCCAACCTGCTCAAGCCGGCCCTG
GCGCGCGGCGAGTTGCGCACCCTGGCGGCCACCACCTGGCTGGAATACAAGAAATACTTCGAGAAGGACCCGGCGCTGAC
CCGGCGCTTCCAGCTGGTCCAGGTCGAGGAGCCGGACGAGGCCACCGCCGTGGAGATGCTGCGCGGCGTCGCCGGCAAGC
TGGAACTGCATCACGGCGTGCAGATCATGGACGCGGCCATCGTCGATGCGGTGAAGCTGTCGCATCGCTACATTTCCGGC
CGCCAGTTGCCGGACAAGGCGATCAGCGTGCTCGACACCGCCTGCGCGCGGGTCGCCCTCGGCCAGCACGACGTGCCGCC
GCCGCTGGAAAGCCTGCGCCATCGCGAGCAGGCGCTGGAAGAGGAATTGCAGCGGCTGCGCCGGGAACAGGCCACCGGCC
TCGACCACAGCGCGCGTATCACCGCCCTGGAAAGCGAGTCGGGCGATAACCGCCGGACCATCCGCGAGCTGGAGACCCGC
TGGGACGAGGAACGCGAAGCGGTGCGCGAACTGCTCGACATCCGCCGCGAACTGCTGGCCCTCAGCGAAAGCGCCGACGC
GGCCAAGCCCGACGAGGAACTGGACGGTCGCATCGACCACCTGGCCGCCGAACTGGCGCGCCTGGCGGCCGGCCTCGAAG
CCATCCGCCAGGACGACCCGCTGGTTCCCGAGCAGGTGGACTCGCGTACCGTGGCCGCGGTGATCGCCGGCTGGACCGGC
ATCCCGGTGGGCAAGATGCTCGCCGACGAAGCCCACGCCATCCGTTCCCTGGCGCAACGAATGGGCCAGCGGGTGATGGG
CCAGGAGGCCGCCCTGGGCGCCATCGCCCAGCGCATCCAGGCCTATCGCGCCGGACTCAGCGACCCGGCCAAGCCGGTCG
GCGTATTCCTCCTGCCCGGCCCCACCGGCGTGGGCAAGACCGAGACCGCCTACGCCCTGGCCGACGCCCTCTACGGCGGC
GAACGCAACCTGATCAGCATCAACCTCTCCGAGTACCAGGAGGCCCACACCGTCAGCCAGCTCAAGGGCGCCCCGCCCGG
CTACGTCGGCTACGGCAGCGGCGGCGTGCTCACCGAAGCGGTGCGCCGCAAGCCCTATTCGGTGGTGCTGCTGGACGAGA
TCGAGAAAGCCCATCCGGACGTGCTGGAAGCCTTCTACAACGTGTTCGACAAGGGCGTGATGGAAGACGGCACCGGCCTG
GTGGTGGACTTCAGGAACACCGTGATCCTCGCCACCAGCAACGTCGGCGCCGAACTGCTGCTGGACAGCCCGGCCGAACA
GGTCGCCACCCCGGCCTTCGACGAGCGCCTGCGCAAAGTCCTGCTGCAAACCTTCCGCCCGGCGTTCCTCGCGCGCATGA
CCGTGGTGCCTTACCGGCCGCTGGAGGAAGCCACCCTGGAAGGCATCGTCGTGGCCAAGCTGGAAAAACTGCGGGAACGC
TACAAGGCCGCTACCGGCAAACAGTTCGACTTCGACCCAGCCATCGTCAAGGCCGTGCTCGCCAAGTGCAGCGCGGCGGG
CGCGCGGGATATCGAGAATGTGTTGATGGCGCAGGTGACGGGGAAGTTGGCGGAGTGGGTGTTGGAGTAG

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (781-848)

• AAA lid domain (AAA_lid_9) (360-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (21-71)

• AAA domain (Cdc48 subfamily) (AAA_2) (611-775)

• ATPase family associated with various cellular activities (AAA) (AAA) (220-332)

3D structure

• AlphaFold DB: Q9I1A8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	37.05	100	0.376