Detailed information NTG0141998

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AU077_RS10355
• Genome accession: NZ_CP013688
• Coordinates: 2034190..2036760 (+)
• Length: 856 a.a.
• NCBI ID: WP_058622001.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus strain ICDDRB-NRC-S1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2029190..2041760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AU077_RS10330 (AU077_10330)	-	2029585..2031085 (+)	1501	Protein_2053	prolyl oligopeptidase family serine peptidase	-
AU077_RS10335 (AU077_10335)	-	2031127..2031420 (-)	294	WP_009855177.1	bacteriocin immunity protein	-
AU077_RS10340 (AU077_10340)	argS	2031532..2033223 (-)	1692	WP_014295461.1	arginine--tRNA ligase	-
AU077_RS10345 (AU077_10345)	argR	2033413..2033850 (+)	438	WP_058621999.1	arginine repressor	-
AU077_RS10350 (AU077_10350)	-	2033847..2034203 (+)	357	WP_058622000.1	YlbF family regulator	-
AU077_RS10355 (AU077_10355)	hexA	2034190..2036760 (+)	2571	WP_058622001.1	DNA mismatch repair protein MutS	Machinery gene
AU077_RS10360 (AU077_10360)	hexB	2036877..2038820 (+)	1944	WP_058621319.1	DNA mismatch repair endonuclease MutL	Machinery gene
AU077_RS10365 (AU077_10365)	ruvA	2038822..2039416 (+)	595	Protein_2060	Holliday junction branch migration protein RuvA	-
AU077_RS12210	-	2039521..2039904 (-)	384	WP_230937552.1	hypothetical protein	-
AU077_RS12215	-	2039873..2040178 (-)	306	WP_230937553.1	hypothetical protein	-
AU077_RS11830	-	2040439..2040582 (+)	144	WP_014295455.1	hypothetical protein	-
AU077_RS10375 (AU077_10375)	-	2040601..2040903 (+)	303	WP_014295454.1	hypothetical protein	-
AU077_RS11255	-	2040953..2041126 (+)	174	WP_196479519.1	hypothetical protein	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96050.29 Da
• Isoelectric Point: 4.8267

>NTDB_id=141998 AU077_RS10355 WP_058622001.1 2034190..2036760(+) (hexA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSFSDFSS
LRSEILNLKAREIVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTVLEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKSVYDIERLASRVSFGKANPKDLLQLGHTLAQVPRIKTILESFESPHLDKLVNSIDTLPELESLIRSAIDP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLAPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAHEQSANLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DNHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TALSTSLTHLVNVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPVVEAE
PITVKSEVAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=141998 AU077_RS10355 WP_058622001.1 2034190..2036760(+) (hexA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTGAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAGGCTGCACAGATTTTAGAGATTAGCTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTCCCTTATCATTCTGCACAACAATACATTGATGTATTAGTG
GAATTGGGTTACAAGGTGGCAATTGCAGAGCAAATGGAAGACCCTAAACAAGCCGTTGGTGTGGTTAAACGTGAAGTTGT
TCAAGTGATTACACCAGGGACTGCGGTTGATTCTTCTAAACCAGATAATGCTAATAATTTCTTGGTGGCTATTGACTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTTTTTCTGATTTTTCAAGT
CTTAGGAGTGAAATTCTGAACCTTAAAGCGCGTGAAATTGTTGTTGGCTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCCTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACGG
TCTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTACACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGCCCTTTGGTGAACCAAGCACAGATTGAGGAACGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTAACGGATAGTCTCAAAAGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCGTTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACCTTGGCACAAGTGCCAAGGATTAAGACAATTTTAGAATCGTTTGAAA
GCCCTCACCTTGATAAGCTTGTCAATAGCATTGACACTTTGCCAGAGCTAGAATCACTTATTCGCTCAGCTATTGACCCA
GATGCCCCTGCTGTTATCACAGAAGGCAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAAGCTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGCGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCTAAAATTGAAGGTGAGATGTTGGAGGCGCATGAGCAATC
AGCAAACTTAGAATATGATATTTTTATGCGCGTTCGTGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAGAATAATCATTATGTTCGTCCAACATTCAAC
GATAACCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTTGTTGAAAAAGTTATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTATGTAGCTGCTGAAAGTGTCAATTTACCAGTGTTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATGACCATATCGGTGCTAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACAAGCTTGACGCATCTTGTCAATGTGCACGTTGCTACCCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGTATCTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGTGGTAGAAGCTGAG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGCACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.963	100	0.72
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382