Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   VU19_RS10760 Genome accession   NZ_CP011068
Coordinates   53746..53841 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain STAB10015     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 48746..58841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VU19_RS00305 (VU19_00305) purK 48815..49888 (+) 1074 WP_021340856.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  VU19_RS00310 (VU19_00310) - 49890..51308 (+) 1419 WP_011888524.1 hypothetical protein -
  VU19_RS00315 (VU19_00315) purB 51328..52620 (+) 1293 WP_011284409.1 adenylosuccinate lyase -
  VU19_RS00320 (VU19_00320) comR 52751..53662 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  VU19_RS10760 comS 53746..53841 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  VU19_RS00325 (VU19_00325) ruvB 53888..54886 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  VU19_RS00330 (VU19_00330) - 55024..55461 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  VU19_RS00335 (VU19_00335) - 55484..55885 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  VU19_RS00340 (VU19_00340) - 55882..57657 (+) 1776 WP_011284411.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=141956 VU19_RS10760 WP_198462994.1 53746..53841(+) (comS) [Streptococcus pyogenes strain STAB10015]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=141956 VU19_RS10760 WP_198462994.1 53746..53841(+) (comS) [Streptococcus pyogenes strain STAB10015]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment