Detailed information NTG0141840

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AUQ45_RS03770
• Genome accession: NZ_CP013672
• Coordinates: 732066..734165 (-)
• Length: 699 a.a.
• NCBI ID: WP_014635413.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain AP53
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 727066..739165

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AUQ45_RS03745 (AUQ45_0732)	-	727543..728382 (+)	840	WP_010922172.1	thymidylate synthase	-
AUQ45_RS03750 (AUQ45_0733)	-	728462..728959 (+)	498	WP_014635412.1	dihydrofolate reductase	-
AUQ45_RS09965 (AUQ45_0734)	-	728979..729149 (+)	171	WP_002984950.1	hypothetical protein	-
AUQ45_RS03755 (AUQ45_0735)	clpX	729279..730508 (+)	1230	WP_002984948.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
AUQ45_RS03760 (AUQ45_0736)	yihA	730518..731117 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
AUQ45_RS03765 (AUQ45_0737)	-	731265..732008 (+)	744	WP_002984942.1	hypothetical protein	-
AUQ45_RS03770 (AUQ45_0738)	clpC	732066..734165 (-)	2100	WP_014635413.1	AAA family ATPase	Regulator
AUQ45_RS03775 (AUQ45_0739)	rpiA	734543..735226 (+)	684	WP_014635414.1	ribose-5-phosphate isomerase RpiA	-
AUQ45_RS03780 (AUQ45_0740)	-	735303..736514 (+)	1212	WP_002984934.1	phosphopentomutase	-
AUQ45_RS03785 (AUQ45_0741)	arsC	736533..736973 (+)	441	WP_010922177.1	arsenate reductase (glutaredoxin)	-
AUQ45_RS03790 (AUQ45_0742)	-	736957..737766 (+)	810	WP_014635415.1	purine-nucleoside phosphorylase	-
AUQ45_RS03795 (AUQ45_0743)	deoD	738429..739142 (+)	714	WP_014635416.1	purine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77361.36 Da
• Isoelectric Point: 5.4562

>NTDB_id=141840 AUQ45_RS03770 WP_014635413.1 732066..734165(-) (clpC) [Streptococcus pyogenes strain AP53]
MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEEFQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLG
TNLTQEARQGHLDPVIGRNKEIQDTAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSL
EAGTQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMDIRNLYEQHHHITLPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAA
QHPVTDLKTLETEIAKQKESQEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMGT
NDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKDAIIRLD
MSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGQQDTETSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKESLEEIVDLMLAEVNQTTAKKGISLTIADDA
KAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVIRQNDQ

Nucleotide

• Length: 2100 bp

>NTDB_id=141840 AUQ45_RS03770 WP_014635413.1 732066..734165(-) (clpC) [Streptococcus pyogenes strain AP53]
ATGACACATTTTTCTGGTAAAGATCCTTTTGTAAATATGGATGATATTTTCAACCAATTAATGGCAAACATGGGTGGTTA
TCGTAGCGAAAATCCCCGCTATCTCGTTAACGGTCGCGAAATAACTCCCGAAGAATTCCAACACTATCGTCAAACAGGAC
AACTCCCTGTAGCGACAACCAAAGCAACAAATTCTCAAATGTTAACACCTAAAGCTGATAGTGTATTGACTCAACTCGGA
ACTAACTTAACACAAGAAGCTCGTCAAGGGCATCTTGACCCCGTCATTGGTCGTAACAAAGAAATTCAAGATACCGCTGA
AATCTTGGCACGACGAACTAAAAATAATCCTGTCCTTGTCGGAGATGCTGGTGTCGGTAAAACTGCAGTCATTGAAGGTT
TAGCTCAAGCCATTGTTAATGGAGATGTCCCAGCTGCTATTAAAAACAAGGAAATCGTATCAATTGATATTTCTAGTCTT
GAAGCTGGTACACAGTATCGTGGTTCCTTTGAAGAGACCATTCAAAACTTGATTCAAGAAGTAAAAGAAGCTGGGAATAT
CATCTTATTTTTTGATGAAATTCATCAAATAGTTGGTGCTGGTGCCACAAGCAGTGATTCAGGCTCAAAGGGACTTGCAG
ATATTCTTAAACCAGCCTTGTCACGAGGAGAATTAACACTGATTGGTGCTACTACTCAAGACGAATACCGCAATACTATT
TTAAAAAATGCTGCTCTTGCTCGTCGCTTTAATGAAGTTAAAGTGAATGCACCATCAGCTGAAGATACTTTTCACATTTT
AATGGATATTCGTAATCTTTATGAACAACACCACCATATTACCCTTCCTGATAATGTTCTAAAAGCTGCTGTTGATTATT
CTATTCAATACATCCCACAGCGTAGCCTGCCAGATAAAGCAATTGACTTACTGGATATGACAGCTGCTCATTTAGCTGCG
CAACACCCGGTCACTGACTTAAAAACACTCGAAACTGAAATAGCTAAACAAAAAGAGAGTCAAGAAAAAGCTGTCGCCAA
AGAAGACTTTGAAAAAGCTTTAGCAGCAAAAACACGGATTGAAACATTACAAAAGCAAATTGAGCAACATAACCAAAGCC
AAAATGTCACTGCTACAGTCAATGATATCGCAGAGTCTGTAGAGCGCTTAACTGGTATTCCTGTCTCTAACATGGGGACT
AATGATTTAGAAAGGCTCAAAGGAATTAGCAGCCGCTTAAAAAGCCATGTCATCGGACAAGATGAGGCTGTCGCAGCAGT
AGCACGTGCTATTCGACGAAATCGGGCAGGTTTTGATGATGGTAACCGTCCAATAGGTTCTTTCCTTTTTGTGGGTCCAA
CTGGTGTTGGTAAAACAGAGTTAGCTAAACAATTAGCACTTGATTTATTTGGCTCCAAAGATGCTATTATTCGACTTGAT
ATGTCCGAATATAACGATCGCACTGCTGTGTCAAAATTGATTGGGACAACGGCTGGTTATGTTGGCTACGATGATAATAA
TAATACCCTAACTGAGCGTGTTCGTCGTAACCCTTATGCTATTGTCTTACTAGATGAAATTGAAAAAGCTGATCCTCAAA
TTATTACACTTCTTCTACAAGTATTAGATGATGGACGATTGACAGATGGACAAGGAAATACTATTAACTTTAAAAATACC
GTTATTATTGCTACATCAAATGCCGGTTTTGGCCAACAAGATACGGAAACTTCTGAGTCTAACATTATGGATCGCATTGC
ACCTTATTTCAGACCAGAGTTTTTGAACCGTTTTAATAGTATCATTAAATTTAATCATCTGCAAAAAGAAAGTTTAGAAG
AAATTGTTGATTTAATGCTAGCTGAAGTAAATCAAACCACCGCAAAAAAAGGTATTAGTTTAACGATTGCTGATGACGCT
AAAGCTCATTTGATAGATTTAGGGTACAATCACGCTATGGGAGCTCGTCCATTACGACGTATTATCGAACAGGAAATTCG
TGACCGTATAACTGATTATTATCTTGACCATCCAGAAGTCAAAAAACTTCAGGCAATCCTAAAAGAAGGACAACTAGTGA
TTAGGCAAAACGATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (259-353)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-600)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (607-678)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	46.799	100	0.471
clpE	Streptococcus mutans UA159	48.913	92.132	0.451
clpE	Streptococcus pneumoniae TIGR4	49.117	89.127	0.438
clpE	Streptococcus pneumoniae Rx1	49.117	89.127	0.438
clpE	Streptococcus pneumoniae D39	49.117	89.127	0.438
clpE	Streptococcus pneumoniae R6	49.117	89.127	0.438
clpC	Bacillus subtilis subsp. subtilis str. 168	44.511	95.136	0.423
clpC	Streptococcus pneumoniae Rx1	41.718	93.276	0.389
clpC	Streptococcus pneumoniae D39	41.718	93.276	0.389
clpC	Streptococcus thermophilus LMD-9	42.633	91.273	0.389
clpC	Streptococcus thermophilus LMG 18311	42.429	90.701	0.385
clpC	Streptococcus pneumoniae TIGR4	42.698	90.129	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.194	93.419	0.385
clpC	Streptococcus mutans UA159	41.562	91.559	0.381