Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FORC12_RS06660 Genome accession   NZ_CP010998
Coordinates   1274026..1274742 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain FORC_012 isolate human sputum     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1269026..1279742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC12_RS06630 (FORC12_1192) - 1269242..1269868 (+) 627 WP_000522384.1 nitroreductase family protein -
  FORC12_RS06635 (FORC12_1193) - 1270229..1271014 (+) 786 WP_000867942.1 carbon-nitrogen family hydrolase -
  FORC12_RS15365 - 1271614..1271748 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  FORC12_RS06645 (FORC12_1195) agrB 1271984..1272553 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  FORC12_RS06650 - 1272550..1272690 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  FORC12_RS06655 - 1272715..1274007 (+) 1293 WP_001789596.1 GHKL domain-containing protein -
  FORC12_RS06660 (FORC12_1197) agrA 1274026..1274742 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  FORC12_RS06665 - 1274814..1274923 (+) 110 Protein_1268 hypothetical protein -
  FORC12_RS06670 (FORC12_1198) - 1275111..1276070 (-) 960 WP_001253305.1 carbohydrate kinase -
  FORC12_RS06675 (FORC12_1199) - 1276067..1277551 (-) 1485 WP_000141430.1 sucrose-6-phosphate hydrolase -
  FORC12_RS06680 (FORC12_1200) - 1277700..1278650 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=141181 FORC12_RS06660 WP_000688492.1 1274026..1274742(+) (agrA) [Staphylococcus aureus strain FORC_012 isolate human sputum]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=141181 FORC12_RS06660 WP_000688492.1 1274026..1274742(+) (agrA) [Staphylococcus aureus strain FORC_012 isolate human sputum]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGCGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment