Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   CUGBS08_RS09025 Genome accession   NZ_CP010874
Coordinates   1776830..1779277 (-) Length   815 a.a.
NCBI ID   WP_017647770.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain CU_GBS_08     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1771830..1784277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CUGBS08_RS09000 (CUGBS08_01814) - 1772111..1773367 (+) 1257 WP_001285395.1 toxic anion resistance protein -
  CUGBS08_RS09005 (CUGBS08_01815) hslO 1773507..1774382 (+) 876 WP_000357828.1 Hsp33 family molecular chaperone HslO -
  CUGBS08_RS09010 (CUGBS08_01816) dusB 1774366..1775343 (+) 978 WP_000192732.1 tRNA dihydrouridine synthase DusB -
  CUGBS08_RS09015 (CUGBS08_01817) - 1775464..1776105 (+) 642 WP_000909523.1 deoxynucleoside kinase -
  CUGBS08_RS09020 (CUGBS08_01818) - 1776119..1776610 (+) 492 WP_000586898.1 GNAT family N-acetyltransferase -
  CUGBS08_RS09025 (CUGBS08_01819) clpC 1776830..1779277 (-) 2448 WP_017647770.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  CUGBS08_RS09030 (CUGBS08_01820) - 1779274..1779738 (-) 465 WP_000985641.1 CtsR family transcriptional regulator -
  CUGBS08_RS09035 (CUGBS08_01821) - 1779911..1780372 (+) 462 WP_001106578.1 COG2426 family protein -
  CUGBS08_RS09040 (CUGBS08_01822) tsf 1780532..1781572 (-) 1041 WP_000808080.1 translation elongation factor Ts -
  CUGBS08_RS09045 (CUGBS08_01823) rpsB 1781666..1782436 (-) 771 WP_000268453.1 30S ribosomal protein S2 -
  CUGBS08_RS09050 (CUGBS08_01824) ahpC 1782713..1783273 (+) 561 WP_000060538.1 alkyl hydroperoxide reductase subunit C -

Sequence

Protein


Download         Length: 815 a.a.        Molecular weight: 90610.09 Da        Isoelectric Point: 5.8782

>NTDB_id=140471 CUGBS08_RS09025 WP_017647770.1 1776830..1779277(-) (clpC) [Streptococcus agalactiae strain CU_GBS_08]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITDYQ
FLEQSSALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDTEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKDKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide


Download         Length: 2448 bp        

>NTDB_id=140471 CUGBS08_RS09025 WP_017647770.1 1776830..1779277(-) (clpC) [Streptococcus agalactiae strain CU_GBS_08]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCGATTATCAA
TTTTTAGAGCAATCATCGGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGTTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
GAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATACAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCCCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCTCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCTTATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGCCATAAGGATAAAAAGCGTAAGCCTATTGCCGTAACCGAA
GATCATATTATGGCAACTCTCAGCCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACCGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAATTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGCTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGATTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCAGAATTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-801)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-132)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

AAA lid domain (AAA_lid_9)

(375-471)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

76.478

99.632

0.762
  clpC Streptococcus thermophilus LMG 18311

72.583

100

0.728
  clpC Streptococcus thermophilus LMD-9

72.46

100

0.726
  clpC Streptococcus pneumoniae TIGR4

68.428

99.877

0.683
  clpC Streptococcus pneumoniae Rx1

68.428

99.877

0.683
  clpC Streptococcus pneumoniae D39

68.428

99.877

0.683
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.558

100

0.496
  clpC Bacillus subtilis subsp. subtilis str. 168

45.324

100

0.464
  clpE Streptococcus mutans UA159

46.395

78.282

0.363

Multiple sequence alignment