Detailed information NTG0140028

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ASZ82_RS02120
• Genome accession: NZ_CP013303
• Coordinates: 422093..424915 (-)
• Length: 940 a.a.
• NCBI ID: WP_000357696.1
• Uniprot ID: Q9KUW5
• Organism: Vibrio cholerae strain CRC711
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 417093..429915

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ASZ82_RS02105 (ASZ82_00411)	lysC	417228..418583 (-)	1356	WP_000102995.1	lysine-sensitive aspartokinase 3	-
ASZ82_RS02110 (ASZ82_00412)	-	419047..420165 (+)	1119	WP_000155556.1	pyridoxal-phosphate-dependent aminotransferase family protein	-
ASZ82_RS02115 (ASZ82_00413)	-	420244..422028 (-)	1785	WP_000212615.1	oligosaccharyltransferase	-
ASZ82_RS02120 (ASZ82_00414)	uvrA	422093..424915 (-)	2823	WP_000357696.1	excinuclease ABC subunit UvrA	Machinery gene
ASZ82_RS02125 (ASZ82_00415)	galU	425071..425943 (-)	873	WP_001920788.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
ASZ82_RS02130 (ASZ82_00416)	qstR	426116..426760 (-)	645	WP_001188316.1	LuxR C-terminal-related transcriptional regulator	Regulator
ASZ82_RS02135 (ASZ82_00417)	ssb	427052..427585 (+)	534	WP_000168289.1	single-stranded DNA-binding protein	Machinery gene
ASZ82_RS02140 (ASZ82_00418)	csrD	427709..429721 (+)	2013	WP_001918202.1	RNase E specificity factor CsrD	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 104327.86 Da
• Isoelectric Point: 6.4814

>NTDB_id=140028 ASZ82_RS02120 WP_000357696.1 422093..424915(-) (uvrA) [Vibrio cholerae strain CRC711]
MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG
EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD
GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML
TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI
SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG
PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV
SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES
RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD
PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH
GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN

Nucleotide

• Length: 2823 bp

>NTDB_id=140028 ASZ82_RS02120 WP_000357696.1 422093..424915(-) (uvrA) [Vibrio cholerae strain CRC711]
ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT
TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG
TCGAATCACTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCATATTGAGGGGCTTTCA
CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACGATTACGGAAGTGTATGACTA
TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGCCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC
AGATGGTAGACAAAGTATTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC
GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC
CGATCCACCGAAACTCGAACTGCACAAAAAGCATACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC
AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTGGAACTTTCCGGCGGTATCGTCGTTGTCGCCCCGATGGAAGGCGAT
GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAACTTGAACCACGCCTGTT
CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA
TTCAAGATGCCAATTTAAGTTTGGCACAAGGTGCGATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG
ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACGCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT
GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTTAAAAAACATCCTTTTG
AAGGAATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTACGTGAGGAGCTGGCAAAATACATC
TCCAACAAGCCTTGCAGCAGCTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGCT
GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA
TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG
CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGTATTCGTCTAGCCAGTCAGATTGGTGCGGGTTTAGTCGGTGT
GATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGCTGCAAACCCTCACCCACTTAC
GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC
CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC
AGGTCAATATCTCAGTGGCGTGAAAAAAATCGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC
TTAAAGGCGCAGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT
TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACAGCACTCAATGGCGCGACGACGGC
GACACCTGCGCCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC
GCACTCCTCGCTCCAACCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTATTTGCAGGAACACAAGAGTCT
CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTTAACGTCCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT
GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAACGCTATAACCGAGAAA
CACTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC
CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGATTGTCCTACATTCGTCTTGGGCAATCAGCCAC
CACCTTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCGCGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA
TTTTGGATGAACCAACCACGGGCCTACACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT
GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGACTGGATCATCGATTTAGGCCCCGAAGG
CGGCCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT
TCCTCAAGCCTTTGTTGAATTAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-236)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-398)

• ABC transporter (ABC_tran) (622-859)

3D structure

• AlphaFold DB: Q9KUW5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.9	100	0.581
uvrA	Streptococcus pneumoniae TIGR4	57.9	100	0.581
uvrA	Streptococcus pneumoniae D39	57.9	100	0.581