Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsA   Type   Regulator
Locus tag   VAA049_RS12290 Genome accession   NZ_CP010811
Coordinates   2700765..2701934 (+) Length   389 a.a.
NCBI ID   WP_001039912.1    Uniprot ID   Q9KM65
Organism   Vibrio cholerae strain 1154-74     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 2695765..2706934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAA049_RS12275 (VAA049_2417) - 2696597..2697586 (-) 990 WP_046122014.1 GTP-binding protein -
  VAA049_RS12280 (VAA049_2418) clcA 2698053..2699459 (+) 1407 WP_000107452.1 H(+)/Cl(-) exchange transporter ClcA -
  VAA049_RS12285 (VAA049_2419) - 2699606..2700568 (+) 963 WP_046122015.1 TDT family transporter -
  VAA049_RS12290 (VAA049_2420) cqsA 2700765..2701934 (+) 1170 WP_001039912.1 alpha-hydroxyketone-type quorum-sensing autoinducer synthase Regulator
  VAA049_RS12295 (VAA049_2421) cqsS 2702037..2704097 (-) 2061 WP_001897118.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator

Sequence

Protein


Download         Length: 389 a.a.        Molecular weight: 43593.61 Da        Isoelectric Point: 6.2272

>NTDB_id=139949 VAA049_RS12290 WP_001039912.1 2700765..2701934(+) (cqsA) [Vibrio cholerae strain 1154-74]
MNKPQLPDFIQNKIDHYIENYFDINKNGKHLVLGKQASPDDIILQSNDYLALANHPLIKARLAKSLLEEQQSLFMSASFL
QNDYDKPMIEKRLAKFTGFDECLLSQSGWNANVGLLQTICQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNNCDHLRM
LIQRHGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAY
RAGAIWCNNEVNRCVPFISYPAIFSSTLLPYEAAGLETTLEIIESADNRRQHLDRMARKLRIGLSQLGLTIRSESQIIGL
ETGDERNTEKVRDYLESNGVFGSVFCRPATSKNKNIIRLSLNSDVNDEQIAKIIEVCSDAVNYGDFYFR

Nucleotide


Download         Length: 1170 bp        

>NTDB_id=139949 VAA049_RS12290 WP_001039912.1 2700765..2701934(+) (cqsA) [Vibrio cholerae strain 1154-74]
ATGAACAAGCCTCAACTTCCTGATTTTATTCAGAACAAGATAGATCACTATATTGAAAATTATTTTGATATAAACAAAAA
CGGTAAACACCTTGTATTGGGTAAACAAGCCAGCCCTGATGACATTATTTTGCAAAGTAATGATTATCTCGCATTGGCCA
ATCATCCGTTGATCAAAGCTCGTTTGGCGAAGTCATTACTGGAAGAACAACAAAGCTTATTTATGTCAGCCTCATTTCTA
CAAAATGACTATGACAAACCCATGATTGAGAAACGTCTGGCTAAGTTCACAGGCTTTGATGAATGTCTATTATCTCAATC
TGGTTGGAATGCAAACGTCGGTTTATTACAAACCATTTGCCAGCCCAATACGAATGTTTACATTGATTTTTTCGCGCACA
TGTCGTTATGGGAAGGGGCGCGCTACGCCAATGCTCAGGCGCATCCTTTTATGCATAATAACTGTGACCATTTACGTATG
CTGATTCAACGTCATGGTCCTGGGATCATTGTCGTAGACTCGATTTACAGCACGTTAGGTACGATTGCACCGCTAGCGGA
ACTGGTCAATATCAGTAAAGAGTTTGGCTGCGCCTTATTAGTCGATGAATCCCACTCTTTGGGCACACATGGCCCTAATG
GTGCAGGTTTATTGGCAGAATTAGGCCTCACTCGTGAAGTGCATTTTATGACCGCAAGTTTGGCCAAAACCTTTGCTTAT
CGCGCAGGAGCCATTTGGTGTAACAATGAAGTGAATCGCTGCGTTCCTTTTATTAGTTATCCAGCTATTTTTAGTTCTAC
TTTGCTGCCTTATGAAGCGGCAGGATTAGAAACGACTTTAGAGATTATTGAATCTGCGGATAATCGTCGTCAGCATTTAG
ATCGTATGGCAAGAAAATTACGCATAGGATTATCCCAGCTGGGATTAACCATTCGCAGTGAAAGCCAAATTATTGGTCTA
GAAACAGGAGATGAACGAAATACCGAAAAAGTTCGGGATTATTTAGAAAGTAATGGAGTGTTTGGCTCAGTATTCTGCCG
CCCGGCAACTTCTAAGAATAAAAACATTATTCGCTTATCACTCAATAGTGATGTGAACGATGAGCAAATCGCCAAAATAA
TTGAGGTTTGCTCTGATGCGGTCAACTACGGTGATTTTTATTTTCGTTAA

Domains

Predicted by InterproScan.

Aminotransferase class I and II (Aminotran_1_2)

(41-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 2WK7
  PDB 2WK8
  PDB 2WK9
  PDB 2WKA
  PDB 3HQT
  PDB 3KKI

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsA Vibrio cholerae strain A1552

100

100

1

Multiple sequence alignment