Detailed information NTG0139645

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: APQ13_RS01350
• Genome accession: NZ_CP013237
• Coordinates: 264216..266798 (+)
• Length: 860 a.a.
• NCBI ID: WP_002289322.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain NG8 isolate Dental Plaque
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 259216..271798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APQ13_RS01330 (APQ13_01330)	murT	259367..260710 (-)	1344	WP_002273823.1	lipid II isoglutaminyl synthase subunit MurT	-
APQ13_RS01335 (APQ13_01335)	cdaA	260819..261673 (+)	855	WP_002263112.1	diadenylate cyclase CdaA	-
APQ13_RS01340 (APQ13_01340)	-	261666..262622 (+)	957	WP_002265809.1	YbbR-like domain-containing protein	-
APQ13_RS01345 (APQ13_01345)	glmM	262673..264022 (+)	1350	WP_002267731.1	phosphoglucosamine mutase	-
APQ13_RS01350 (APQ13_01350)	clpC	264216..266798 (+)	2583	WP_002289322.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
APQ13_RS01355 (APQ13_01355)	lpdA	267027..268364 (+)	1338	WP_002269437.1	dihydrolipoyl dehydrogenase	-
APQ13_RS01360 (APQ13_01360)	-	268390..269463 (+)	1074	WP_002267204.1	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	-
APQ13_RS01365 (APQ13_01365)	-	269476..270507 (+)	1032	WP_002267205.1	alpha-ketoacid dehydrogenase subunit beta	-
APQ13_RS01370 (APQ13_01370)	-	270521..271774 (+)	1254	WP_002276694.1	dihydrolipoamide acetyltransferase family protein	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98080.67 Da
• Isoelectric Point: 6.4498

>NTDB_id=139645 APQ13_RS01350 WP_002289322.1 264216..266798(+) (clpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
MIDKMTQLVEDSLEEAKELAIAHRNYQLDIPHLWAVLVKPDQFAFQFYQSLEINTNQLIEIINKEIDKIPVLSSTEKSSY
ARLYSQRLKNLLDDAHREMIDLKDQVLTVEHLILALFNQQRNPITVFLLEQGLNKEKLYQKMHRIRKGKPAISSSQETIY
DALEKYAVNLNQRALDEPVNKIIGRQNEMNDIIRILSRKNKNNAVLVGHSGVGKTAIIEGFVQRLVKNQVPKNLRGKIIY
SLDIGALLAGTKYRGEFEERFKALLNDIIDSNGQIILFIDEIHSIVSAGRTEGSVDAASILKPLLARGKIRIIGSTTHAE
YRESIEYDRALERRFQRILVHEPDLDYTMEILKGLKPIYENFHGVRLEEDSLEAAASLSKRYISDRFLPDKALDLIDEAC
AAKRLASHAYPVQMTNLSQQLISEKIRLLRLTDSDTDDKFKLNSHLEQLEEQKSQLLANWQRERELLDQVQELRSHLTAL
EEQANLALENNQVADYVRLEDEEIKICHQKMTALEKERLDSQKIINVTVTREDIAAVVERLTGIKVQGVMENERDRLLHL
EELLHQKIVGQDQAVQKVSQAIIRSRAGIQNPKRPIGSFLFLGPTGVGKTALAKRLAEVLFGSELEMVRLDMSEYMEKHA
VARLVGPPPGYVGYEEGGQLTEAVRQRLYSIVLLDEIEKAHPDVFNTLLQVLDEGRLTDSKGRTIDFKNTILIMTSNIGS
TNILQSLQDSGCITSEVRHKVLDELNHSFRPEFLNRIDETVLFNALSEKDMIGVVKVMVSDLQARLLEQDVHLTLTESVY
TLLAKEGFDAAFGARPMQRTIMQKLENPLALHLIQNQKNKEKETFVTVSVKDKKLKFTFS

Nucleotide

• Length: 2583 bp

>NTDB_id=139645 APQ13_RS01350 WP_002289322.1 264216..266798(+) (clpC) [Streptococcus mutans strain NG8 isolate Dental Plaque]
ATGATCGATAAAATGACTCAGTTAGTTGAAGATTCTTTAGAAGAAGCAAAGGAATTGGCTATTGCTCATCGTAATTATCA
GCTGGACATTCCCCATTTATGGGCTGTCTTGGTAAAACCTGATCAATTTGCTTTTCAATTCTATCAATCTTTAGAAATAA
ATACCAATCAGCTGATTGAGATTATCAATAAAGAAATAGATAAAATCCCAGTCCTTTCAAGTACAGAAAAAAGCAGTTAT
GCACGTTTATACAGTCAGCGTTTAAAAAATTTATTGGATGACGCACATCGGGAAATGATTGATTTAAAGGATCAGGTGCT
GACTGTAGAACACTTGATCTTGGCACTTTTTAACCAACAACGCAATCCCATTACTGTTTTTTTGCTTGAACAGGGTCTAA
ACAAAGAAAAACTTTATCAAAAGATGCATAGGATTCGTAAAGGGAAACCTGCTATTTCTTCCAGTCAAGAAACTATTTAT
GATGCTTTAGAAAAGTATGCTGTCAACTTAAATCAGCGTGCTTTAGATGAACCTGTTAATAAAATTATTGGCCGTCAGAA
TGAAATGAATGATATTATTCGTATTTTATCGCGTAAGAATAAGAATAATGCCGTTTTGGTTGGTCATTCAGGTGTTGGAA
AAACAGCCATTATTGAAGGATTTGTTCAGCGGTTAGTTAAAAATCAAGTTCCGAAAAATTTGCGAGGTAAGATCATTTAC
AGTCTTGACATAGGAGCCTTGCTGGCAGGAACTAAATACCGCGGTGAATTTGAAGAACGTTTCAAAGCTCTTCTCAATGA
TATTATAGACTCAAACGGTCAGATTATTCTTTTCATAGATGAAATTCATTCTATTGTCAGTGCAGGACGGACAGAGGGTT
CTGTTGATGCGGCCAGTATTTTGAAGCCGCTTTTGGCTAGAGGAAAAATTAGAATTATTGGTTCCACTACCCATGCAGAA
TACCGTGAAAGTATTGAATACGATAGGGCGTTAGAAAGACGTTTTCAAAGGATCTTAGTTCATGAACCAGATCTTGATTA
TACCATGGAAATTCTTAAAGGTCTCAAGCCCATTTATGAAAATTTTCATGGTGTCAGACTTGAAGAAGATAGTTTGGAAG
CTGCCGCAAGCTTGTCCAAGCGTTATATTTCTGATCGCTTTTTGCCAGATAAGGCTCTGGATTTAATTGACGAAGCCTGT
GCTGCTAAGCGGCTTGCTTCTCATGCTTATCCCGTGCAAATGACCAATTTGTCTCAGCAACTTATTTCTGAGAAAATTCG
TTTATTGCGTTTGACCGATTCTGACACTGACGATAAGTTTAAATTAAACAGTCATCTTGAGCAATTAGAGGAGCAAAAAA
GCCAATTATTAGCAAATTGGCAAAGGGAAAGAGAGCTCCTAGATCAGGTACAAGAGCTTCGTTCACATTTAACGGCTTTA
GAAGAGCAGGCTAATCTTGCTCTTGAAAATAATCAAGTCGCAGATTATGTCCGTCTAGAAGATGAGGAAATAAAGATATG
TCATCAAAAGATGACAGCTTTAGAAAAGGAACGTTTAGACAGTCAGAAGATAATTAATGTTACTGTGACTAGAGAAGATA
TAGCAGCTGTTGTTGAACGCTTGACAGGCATCAAAGTACAGGGTGTTATGGAAAACGAGCGTGATCGTCTCTTGCACTTA
GAAGAATTATTGCACCAAAAAATTGTTGGTCAAGATCAAGCCGTACAAAAGGTATCTCAGGCCATCATTCGCTCTCGTGC
TGGCATTCAAAACCCTAAACGTCCAATTGGCTCCTTCCTCTTTTTGGGACCGACTGGTGTGGGGAAAACAGCGCTTGCTA
AACGTTTGGCGGAAGTTCTTTTTGGCAGTGAACTTGAGATGGTGCGTCTCGATATGTCTGAATATATGGAAAAACATGCT
GTCGCACGTTTAGTAGGACCACCACCAGGTTATGTCGGATATGAAGAAGGAGGCCAATTAACTGAGGCTGTTCGTCAGCG
CTTATACTCTATCGTCCTACTTGATGAGATTGAAAAAGCTCATCCTGATGTTTTTAATACCTTACTGCAGGTTTTAGATG
AAGGGCGTTTGACGGATTCAAAAGGGCGAACCATTGATTTTAAAAATACCATCTTAATTATGACCAGCAATATTGGCTCA
ACCAATATTTTACAAAGTCTGCAAGATAGTGGCTGCATTACTTCAGAAGTCCGTCATAAAGTTCTAGATGAGCTGAATCA
CAGTTTCAGACCAGAGTTTCTTAATCGGATTGATGAGACGGTACTCTTTAATGCTCTTTCTGAAAAAGATATGATAGGTG
TTGTTAAGGTCATGGTTTCTGATTTGCAAGCTCGCCTCTTAGAACAAGATGTTCATCTGACATTGACTGAATCGGTTTAT
ACCCTCTTAGCTAAAGAAGGTTTTGATGCAGCTTTTGGTGCCAGACCCATGCAGAGGACAATTATGCAAAAGTTAGAAAA
CCCTTTGGCTTTACATCTTATTCAAAATCAGAAAAATAAAGAAAAAGAGACTTTTGTGACAGTATCTGTTAAGGATAAGA
AACTCAAATTCACATTCTCATAG

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (594-759)

• ATPase family associated with various cellular activities (AAA) (AAA) (205-338)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-842)

• AAA lid domain (AAA_lid_9) (346-436)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-66)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	40.904	100	0.41
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.175	100	0.383
clpC	Streptococcus pneumoniae Rx1	38.037	94.767	0.36
clpC	Streptococcus pneumoniae D39	38.037	94.767	0.36
clpC	Streptococcus pneumoniae TIGR4	38.177	94.419	0.36