Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SB45_RS05480 Genome accession   NZ_CP010556
Coordinates   1082218..1082874 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain L-H15     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1077218..1087874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SB45_RS05455 (SB45_05455) oppF 1077747..1078664 (+) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -
  SB45_RS05460 (SB45_05460) - 1078771..1079958 (+) 1188 WP_043866988.1 putative glycoside hydrolase -
  SB45_RS05465 (SB45_05465) - 1080076..1080654 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  SB45_RS05470 (SB45_05470) spx 1080833..1081228 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  SB45_RS05475 (SB45_05475) - 1081286..1081942 (-) 657 WP_003155033.1 TerC family protein -
  SB45_RS05480 (SB45_05480) mecA 1082218..1082874 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  SB45_RS05485 (SB45_05485) - 1083025..1084185 (+) 1161 WP_043866989.1 competence protein CoiA family protein -
  SB45_RS05490 (SB45_05490) pepF 1084413..1086242 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  SB45_RS19785 (SB45_05495) - 1086280..1086447 (-) 168 WP_003155026.1 hypothetical protein -
  SB45_RS05500 (SB45_05500) spxH 1086733..1087635 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=139246 SB45_RS05480 WP_003155032.1 1082218..1082874(+) (mecA) [Bacillus velezensis strain L-H15]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=139246 SB45_RS05480 WP_003155032.1 1082218..1082874(+) (mecA) [Bacillus velezensis strain L-H15]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment