Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   AKK22_RS25665 Genome accession   NZ_CP013029
Coordinates   4829850..4830842 (-) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli strain 2012C-4227     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4824850..4835842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AKK22_RS25655 (AKK22_25155) yieP 4827742..4828434 (+) 693 WP_001131169.1 FadR/GntR family transcriptional regulator -
  AKK22_RS25660 (AKK22_25160) mdtD 4828457..4829884 (+) 1428 WP_001280838.1 multidrug transporter subunit MdtD -
  AKK22_RS25665 (AKK22_25165) cytR 4829850..4830842 (-) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  AKK22_RS25670 (AKK22_25170) rbsK 4830846..4831775 (-) 930 WP_001300603.1 ribokinase -
  AKK22_RS25675 (AKK22_25175) rbsB 4831901..4832791 (-) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  AKK22_RS25680 (AKK22_25180) rbsC 4832816..4833781 (-) 966 WP_000211858.1 ribose ABC transporter permease -
  AKK22_RS25685 (AKK22_25185) rbsA 4833785..4835290 (-) 1506 WP_032207986.1 ribose ABC transporter ATP-binding protein RbsA -
  AKK22_RS25690 (AKK22_25190) rbsD 4835298..4835717 (-) 420 WP_032208010.1 D-ribose pyranase -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=138481 AKK22_RS25665 WP_000224470.1 4829850..4830842(-) (cytR) [Escherichia coli strain 2012C-4227]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=138481 AKK22_RS25665 WP_000224470.1 4829850..4830842(-) (cytR) [Escherichia coli strain 2012C-4227]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCCTTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364

Multiple sequence alignment