Detailed information NTG0137697

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACT74_RS08060
• Genome accession: NZ_CP012958
• Coordinates: 1689012..1691582 (+)
• Length: 856 a.a.
• NCBI ID: WP_014167565.1
• Uniprot ID: -
• Organism: Aggregatibacter actinomycetemcomitans strain VT1169
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1684012..1696582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACT74_RS08035 (ACT74_08030)	nfuA	1684452..1685036 (-)	585	WP_005589244.1	Fe-S biogenesis protein NfuA	-
ACT74_RS08040 (ACT74_08035)	-	1685153..1685839 (-)	687	WP_005568674.1	DNA utilization protein GntX	-
ACT74_RS08045 (ACT74_08040)	-	1685985..1686797 (+)	813	WP_005568673.1	Cof-type HAD-IIB family hydrolase	-
ACT74_RS08050 (ACT74_08045)	asd	1686981..1688093 (+)	1113	WP_005569603.1	aspartate-semialdehyde dehydrogenase	-
ACT74_RS08055 (ACT74_08050)	-	1688166..1688747 (-)	582	WP_041915469.1	ComEA family DNA-binding protein	-
ACT74_RS08060 (ACT74_08055)	clpC	1689012..1691582 (+)	2571	WP_014167565.1	ATP-dependent chaperone ClpB	Regulator
ACT74_RS08065 (ACT74_08060)	-	1691684..1692184 (-)	501	WP_005545169.1	surface-adhesin E family protein	-
ACT74_RS08070 (ACT74_08065)	purM	1692367..1693395 (+)	1029	WP_061869958.1	phosphoribosylformylglycinamidine cyclo-ligase	-
ACT74_RS08075 (ACT74_08070)	-	1693395..1693574 (+)	180	WP_005544245.1	hypothetical protein	-
ACT74_RS08080 (ACT74_08075)	dapF	1693653..1694477 (+)	825	WP_061869959.1	diaminopimelate epimerase	-
ACT74_RS08085 (ACT74_08080)	xerC	1694487..1695377 (+)	891	WP_005544248.1	tyrosine recombinase XerC	-
ACT74_RS08090 (ACT74_08085)	-	1695391..1696104 (+)	714	WP_005545162.1	HAD-IA family hydrolase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95809.30 Da
• Isoelectric Point: 5.1519

>NTDB_id=137697 ACT74_RS08060 WP_014167565.1 1689012..1691582(+) (clpC) [Aggregatibacter actinomycetemcomitans strain VT1169]
MNIEKFTTKFQQALAEAQSLAVGKDNQFIEPVHLLSALLNQQDGSIAPILTTGGVNVALLRNEINNELAKLPQVSGNGGD
VQISRQLLNILNLCDKLAQQRQDKFISSEIFLLAALEEKGTLSEILKKCGAKKEQILQAIEQIRGGQKVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLNELAKEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVGEPSVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPQPLDRLDRRIIQLKLEQQALQKEDDDASRKRLEMLEKELAEKEREYAELEEVWKSEKAALSGTQHIKAELE
NARTQMEQARRAGDLSKMSELQYGKIPDLEKQLAQAEGAEGKEMSLLRYRVTDEEIAEVLSRATGIPVAKMMEGEKEKLL
HMEEFLHKRVIGQNEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALASFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQDHAQEGYDTVKSMVMEVVGHYFRPEFINRIDETVMFHPLNKENIRQIADIQLRRLTRRMETHGYVLNFTDATLD
FISDIGYDPIFGARPLKRAIQQEIENPLAQQILSGALLPDKVIDVDYVDGQIVAKQ

Nucleotide

• Length: 2571 bp

>NTDB_id=137697 ACT74_RS08060 WP_014167565.1 1689012..1691582(+) (clpC) [Aggregatibacter actinomycetemcomitans strain VT1169]
ATGAATATTGAAAAATTTACCACAAAATTCCAACAAGCCTTGGCGGAAGCACAATCTTTGGCGGTCGGCAAGGATAATCA
ATTTATTGAACCGGTACATTTATTGAGCGCCTTGTTAAATCAACAAGACGGTTCCATAGCACCGATTCTCACCACCGGCG
GCGTAAACGTCGCTTTATTGCGTAACGAAATCAACAACGAGCTTGCCAAGCTCCCGCAAGTGTCCGGCAACGGCGGCGAT
GTGCAAATTTCCCGTCAGTTGCTTAACATCTTGAATTTATGTGACAAATTGGCACAACAACGGCAGGATAAATTTATTTC
GTCCGAAATCTTTTTGCTTGCCGCTTTAGAAGAAAAAGGTACCCTGAGCGAGATTTTGAAAAAGTGCGGTGCGAAAAAAG
AACAGATTTTACAAGCCATCGAGCAGATTCGCGGAGGACAAAAAGTGAATGATCAAAATGCGGAAGAAAGCCGCCAAGCA
CTCGAAAAATATACTATCGACTTAACCGCCCGCGCAGAAAGCGGCAAATTGGATCCGGTGATTGGACGTGACGAGGAAAT
CCGCCGCACCATTCAAGTGTTGCAGCGCCGTACCAAAAACAATCCGGTGCTTATCGGTGAACCGGGTGTGGGTAAAACCG
CCATTGTGGAAGGTTTGGCACAGCGTATCGTGAACGGCGAAGTGCCGGAAGGGTTGAAAAACAAACGTGTGCTGTCGCTT
GATATGGGCGCGTTAATCGCCGGGGCGAAATATCGCGGCGAATTTGAAGAACGTTTGAAAGCGGTGTTAAACGAACTCGC
CAAAGAAGAAGGCAGAGTGATTTTGTTCATCGATGAAATTCACACTATGGTGGGCGCGGGTAAAACCGACGGCGCCATGG
ACGCAGGCAACCTGCTCAAACCAAGTTTGGCGCGCGGTGAATTGCATTGCGTGGGCGCCACTACCTTGGATGAATATCGT
CAATACATTGAAAAAGACGCGGCGCTTGAACGTCGTTTCCAAAAAGTGTTTGTGGGCGAACCGAGCGTGGAAGACACCAT
CGCCATTTTGCGCGGTTTGAAAGAGCGTTATGAAATCCACCACCATGTACAAATTACCGACCCGGCAATCGTGGCGGCGG
CAACGCTTTCTCATCGTTATATTTCCGATCGTCAGTTGCCGGATAAAGCCATCGACTTAATCGACGAAGCGGCATCCAGC
ATTCGGATGGAAATTGACTCCAAACCGCAACCGTTAGATCGTTTGGATCGCCGTATTATCCAGCTCAAACTGGAACAACA
GGCGTTGCAAAAAGAAGATGACGATGCCAGCCGTAAACGTTTGGAAATGCTGGAAAAAGAATTGGCGGAAAAAGAACGTG
AATATGCCGAATTAGAAGAAGTGTGGAAATCGGAAAAAGCCGCGCTGTCCGGCACGCAACACATTAAAGCGGAATTGGAA
AATGCCCGCACGCAAATGGAACAAGCACGCCGCGCTGGTGATTTAAGCAAAATGTCCGAATTGCAATACGGCAAAATTCC
GGATTTGGAAAAACAATTAGCCCAAGCGGAAGGTGCCGAGGGCAAAGAAATGAGTCTGTTACGCTATCGCGTGACCGACG
AAGAAATCGCCGAAGTGCTTTCCCGCGCTACCGGTATTCCGGTCGCTAAAATGATGGAAGGCGAAAAAGAAAAATTATTG
CACATGGAAGAATTTCTGCACAAACGGGTTATCGGTCAAAACGAAGCGGTGGATGCCGTGGCGAACGCTATTCGTCGTAG
CCGCGCCGGTCTTTCCGATCCGAACCGTCCGATTGGTTCCTTCTTATTCTTAGGTCCGACCGGTGTGGGTAAAACCGAGT
TGTGCAAAGCCTTGGCGTCCTTCTTATTCGACAGCGAAGATGCCATGGTGCGTATCGATATGTCCGAGTTCATGGAAAAA
CACAGCGTGTCCCGTTTGGTGGGCGCACCTCCGGGCTATGTGGGCTATGAAGAAGGCGGTTACTTAACCGAAGCGGTGCG
TCGCCGTCCGTATTCCGTGATTTTGCTCGACGAAGTGGAAAAAGCGCATCACGATGTGTTTAACATTCTGTTGCAAGTGT
TGGACGACGGTCGTCTCACCGACGGACAGGGCAGAACCGTGGATTTCCGCAATACGGTGGTGATTATGACCTCCAACCTC
GGTTCCGACTTGATTCAGGATCACGCACAGGAAGGGTACGACACCGTGAAAAGCATGGTGATGGAAGTGGTCGGTCATTA
TTTCCGTCCGGAATTTATCAACCGTATCGACGAAACCGTCATGTTCCACCCGTTGAACAAAGAAAATATTCGTCAAATTG
CCGATATTCAATTAAGACGCTTAACCCGTCGCATGGAAACTCATGGCTATGTGTTGAACTTTACCGATGCTACCCTTGAT
TTCATCAGCGACATCGGTTACGACCCGATTTTCGGTGCACGTCCGCTCAAACGGGCAATTCAGCAAGAAATCGAAAATCC
GTTGGCACAACAAATTTTATCCGGCGCCTTGCTGCCTGATAAAGTGATTGATGTGGACTACGTGGACGGTCAAATCGTGG
CAAAACAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-843)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.011	100	0.478
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.956	100	0.435
clpE	Streptococcus mutans UA159	49.415	79.907	0.395
clpE	Streptococcus pneumoniae TIGR4	49.19	79.322	0.39
clpE	Streptococcus pneumoniae R6	49.19	79.322	0.39
clpE	Streptococcus pneumoniae Rx1	49.19	79.322	0.39
clpE	Streptococcus pneumoniae D39	49.19	79.322	0.39
clpC	Lactococcus lactis subsp. cremoris KW2	48.191	80.724	0.389