Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   SD90_RS05830 Genome accession   NZ_CP010450
Coordinates   1166428..1167465 (-) Length   345 a.a.
NCBI ID   WP_032462841.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS638     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1161428..1172465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD90_RS05810 (SD90_05825) - 1162176..1162802 (+) 627 WP_002983834.1 prepilin peptidase -
  SD90_RS05815 (SD90_05830) rlmN 1162884..1163963 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  SD90_RS05820 (SD90_05835) - 1163967..1164587 (-) 621 WP_023610891.1 YutD family protein -
  SD90_RS05825 (SD90_05840) - 1165035..1166012 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  SD90_RS05830 (SD90_05845) sepM 1166428..1167465 (-) 1038 WP_032462841.1 SepM family pheromone-processing serine protease Regulator
  SD90_RS05835 (SD90_05850) coaD 1167452..1167943 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  SD90_RS05840 (SD90_05855) rsmD 1167933..1168472 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SD90_RS05845 (SD90_05860) asnA 1168595..1169587 (-) 993 WP_032462840.1 aspartate--ammonia ligase -
  SD90_RS05850 (SD90_05865) arcC 1169900..1170850 (-) 951 WP_010922501.1 carbamate kinase -
  SD90_RS05855 (SD90_05870) - 1170870..1172201 (-) 1332 WP_011285641.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37568.31 Da        Isoelectric Point: 9.7472

>NTDB_id=137399 SD90_RS05830 WP_032462841.1 1166428..1167465(-) (sepM) [Streptococcus pyogenes strain NGAS638]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDKVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=137399 SD90_RS05830 WP_032462841.1 1166428..1167465(-) (sepM) [Streptococcus pyogenes strain NGAS638]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACAAAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-192)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.565

100

0.696

Multiple sequence alignment