Detailed information NTG0137392

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: SD90_RS04250
• Genome accession: NZ_CP010450
• Coordinates: 852941..853777 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NGAS638
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 847941..858777

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SD90_RS04220 (SD90_04225)	-	848423..848863 (+)	441	WP_032462918.1	hypothetical protein	-
SD90_RS04225 (SD90_04230)	-	848913..849824 (-)	912	WP_053301460.1	diacylglycerol/lipid kinase family protein	-
SD90_RS04230 (SD90_04235)	trhA	849941..850591 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
SD90_RS04235 (SD90_04240)	-	850588..851028 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
SD90_RS04240 (SD90_04245)	ylqF	851247..852095 (+)	849	WP_002995004.1	ribosome biogenesis GTPase YlqF	-
SD90_RS04245 (SD90_04250)	-	852085..852876 (+)	792	WP_002995007.1	ribonuclease HII	-
SD90_RS04250 (SD90_04255)	dprA	852941..853777 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
SD90_RS04255 (SD90_04260)	topA	853884..856013 (+)	2130	WP_002984618.1	type I DNA topoisomerase	-
SD90_RS04260 (SD90_04265)	trmFO	856148..857494 (+)	1347	WP_032462917.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=137392 SD90_RS04250 WP_002995009.1 852941..853777(+) (dprA) [Streptococcus pyogenes strain NGAS638]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=137392 SD90_RS04250 WP_002995009.1 852941..853777(+) (dprA) [Streptococcus pyogenes strain NGAS638]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367