Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   SD89_RS06660 Genome accession   NZ_CP010449
Coordinates   1340036..1341073 (-) Length   345 a.a.
NCBI ID   WP_011284961.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NGAS322     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1335036..1346073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SD89_RS10160 (SD89_06660) - 1335784..1336411 (+) 628 Protein_1275 prepilin peptidase -
  SD89_RS06645 (SD89_06665) rlmN 1336493..1337572 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  SD89_RS06650 (SD89_06670) - 1337576..1338196 (-) 621 WP_053308499.1 YutD family protein -
  SD89_RS06655 (SD89_06675) - 1338644..1339621 (-) 978 WP_053308500.1 LacI family DNA-binding transcriptional regulator -
  SD89_RS06660 (SD89_06680) sepM 1340036..1341073 (-) 1038 WP_011284961.1 SepM family pheromone-processing serine protease Regulator
  SD89_RS06665 (SD89_06685) coaD 1341060..1341551 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  SD89_RS06670 (SD89_06690) rsmD 1341541..1342080 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SD89_RS06675 (SD89_06695) asnA 1342203..1343195 (-) 993 WP_053308501.1 aspartate--ammonia ligase -
  SD89_RS06680 (SD89_06700) arcC 1343508..1344458 (-) 951 WP_053308502.1 carbamate kinase -
  SD89_RS06685 (SD89_06705) - 1344478..1345809 (-) 1332 WP_032460502.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=137342 SD89_RS06660 WP_011284961.1 1340036..1341073(-) (sepM) [Streptococcus pyogenes strain NGAS322]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=137342 SD89_RS06660 WP_011284961.1 1340036..1341073(-) (sepM) [Streptococcus pyogenes strain NGAS322]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment