Detailed information NTG0137325

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: APV63_RS01320
• Genome accession: NZ_CP012905
• Coordinates: 266024..268594 (+)
• Length: 856 a.a.
• NCBI ID: WP_060472908.1
• Uniprot ID: -
• Organism: Helicobacter pylori strain 7C
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 261024..273594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APV63_RS01295 (APV63_01295)	xseA	261326..262588 (+)	1263	WP_060472904.1	exodeoxyribonuclease VII large subunit	-
APV63_RS01300 (APV63_01300)	-	262607..263779 (-)	1173	WP_080391053.1	DNA methyltransferase	-
APV63_RS01305 (APV63_01305)	-	263772..264386 (-)	615	WP_060472905.1	hypothetical protein	-
APV63_RS01310 (APV63_01310)	-	264501..265196 (+)	696	Protein_250	BsaWI family type II restriction enzyme	-
APV63_RS01315 (APV63_01315)	-	265193..265951 (+)	759	WP_060472907.1	DNA-methyltransferase	-
APV63_RS01320 (APV63_01320)	clpC	266024..268594 (+)	2571	WP_060472908.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
APV63_RS01325 (APV63_01325)	-	268650..269369 (+)	720	WP_001874905.1	cytochrome c biogenesis protein CcdA	-
APV63_RS01330 (APV63_01330)	-	269379..270514 (+)	1136	Protein_254	amidohydrolase family protein	-
APV63_RS01335 (APV63_01335)	mqnF	270499..271728 (+)	1230	WP_060472909.1	aminofutalosine deaminase family hydrolase	-
APV63_RS01340 (APV63_01340)	-	271789..272031 (+)	243	WP_060472910.1	nuclease	-
APV63_RS01345 (APV63_01345)	miaB	272041..273354 (+)	1314	WP_080391054.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 96777.83 Da
• Isoelectric Point: 6.4328

>NTDB_id=137325 APV63_RS01320 WP_060472908.1 266024..268594(+) (clpC) [Helicobacter pylori strain 7C]
MNLFEKMTDQLHEALDSALALALHHKNAEVTPLHVLFAMLNNSQGILIQALQKMPVDIEALKLSVQSELHKFAKVSQISK
QNIQLNQALIQSLENAQGLMAKRGDSFIATDVYLLANMSLFESVLKPYLDTKELQKTLESLRKGRIIQDKNDDSNLESLE
KFGIDLTQKALENKLDPVIGRDEEIIRMMQILIRKTKNNPILLGEPGVGKTAVVEGLAQRIVNKEVPKTLLNKRVIALDL
SLLVAGAKYRGEFEERLKKVIEEVKKSANVILFIDEIHTIVGAGASEGGMDAANILKPVLARGELHTIGATTLKEYRKYF
EKDMALQRRFQPILLNEPSINEALQILRGLKETLETHHNITINDSALIASAKLSSRYITDRFLPDKAIDLIDEGAAQLKM
QMESEPAKLSSVKRSIQRLEMERQALEMEKKESNAKRMQEILKELSDLKEEKIQLEAQFENEKEVFKEISRLKMEMENLK
KEAERFKRNGDYQQAGEIEYSKIPENKKKEEELQRKWEAMQQNGALLQNALTENNIAEIVSQWTHIPVQKMLQSEKNRVL
NIESELQKRVVGQEKALKAIAKAIKRNKAGLSDSNKPIGSFLFLGPTGVGKTESAKALAQFLFDSDKNLIRIDMSEYMEK
HAISRLIGAAPGYVGYEEGGQLTEAVRRKPYSVVLLDEVEKAHPDVFNLLLQVLDEGHLTDSKGVRVDFKNTILILTSNV
ASGALLEENLSEAEKQKAIKESLRQFFKPEFLNRLDEIISFNALDSHAIINIVGILFENIQKKALERGINITLDEKAKEL
IAEVGFDRFYGARPLKRALYEMVEDKLAELILEDKIKENDSVAFVVENNEIVPKIK

Nucleotide

• Length: 2571 bp

>NTDB_id=137325 APV63_RS01320 WP_060472908.1 266024..268594(+) (clpC) [Helicobacter pylori strain 7C]
ATGAATTTATTTGAAAAAATGACTGACCAATTGCATGAGGCTTTAGACAGCGCGCTCGCTCTAGCTTTACACCATAAAAA
CGCTGAAGTAACGCCCTTACATGTGCTTTTTGCCATGCTTAATAACTCCCAAGGCATTCTCATTCAAGCCTTACAAAAAA
TGCCTGTGGATATTGAAGCTTTAAAACTTAGCGTTCAAAGCGAGTTGCATAAGTTCGCTAAAGTCTCACAAATCAGCAAG
CAAAATATCCAATTAAACCAAGCTTTAATCCAAAGTTTAGAAAACGCTCAAGGCTTGATGGCTAAAAGGGGCGATTCTTT
CATCGCTACCGATGTGTATCTTTTGGCGAACATGAGCCTTTTTGAAAGCGTTCTAAAGCCTTATTTAGACACTAAGGAAT
TGCAAAAAACTTTAGAATCTTTAAGAAAAGGCAGGATTATCCAGGATAAAAACGATGATTCCAATTTGGAAAGTTTAGAA
AAATTTGGCATTGATTTGACGCAAAAAGCCCTAGAAAATAAGCTGGATCCGGTGATCGGAAGAGATGAAGAAATCATTCG
CATGATGCAAATTTTGATAAGAAAAACAAAAAATAACCCTATTTTATTGGGTGAGCCTGGAGTGGGGAAAACGGCGGTTG
TAGAAGGGTTAGCCCAACGCATTGTGAATAAGGAAGTGCCTAAAACGCTTTTAAACAAACGAGTCATCGCTTTAGATTTG
AGCTTATTGGTGGCTGGGGCGAAATACAGAGGCGAGTTTGAAGAGCGCCTGAAAAAGGTGATTGAAGAAGTTAAAAAAAG
CGCGAATGTGATTTTATTCATTGATGAAATCCACACGATTGTAGGGGCTGGGGCTAGTGAGGGGGGCATGGATGCGGCGA
ATATTTTAAAACCCGTGCTCGCTAGGGGGGAATTGCACACGATTGGAGCGACCACTTTAAAAGAATACCGCAAGTATTTT
GAAAAAGACATGGCGCTACAAAGGCGTTTCCAACCTATTTTACTCAATGAGCCTAGCATCAATGAAGCTTTACAGATTTT
AAGGGGGTTGAAAGAAACTTTAGAAACGCACCATAATATCACCATCAATGACTCCGCGCTCATAGCGAGCGCCAAACTCT
CCAGCCGTTATATCACCGATAGGTTTTTACCCGATAAAGCGATTGATTTGATTGATGAGGGGGCGGCCCAATTAAAAATG
CAAATGGAATCAGAGCCGGCCAAACTCTCTAGCGTTAAACGCTCCATTCAAAGACTAGAAATGGAAAGACAAGCCCTTGA
AATGGAAAAAAAAGAGAGCAATGCCAAACGCATGCAAGAAATCCTTAAAGAATTGAGCGATTTGAAAGAAGAAAAAATCC
AATTAGAAGCGCAATTTGAAAACGAGAAAGAAGTGTTCAAAGAAATTTCACGCTTGAAAATGGAAATGGAAAATTTGAAA
AAAGAGGCTGAAAGGTTTAAGCGCAACGGGGATTACCAGCAAGCGGGTGAAATTGAATACTCTAAAATCCCTGAAAATAA
AAAGAAAGAAGAAGAATTGCAGCGTAAATGGGAAGCGATGCAACAAAACGGGGCGTTATTGCAAAACGCTTTAACCGAAA
ACAACATCGCTGAGATCGTGAGCCAATGGACGCACATCCCGGTCCAAAAAATGCTCCAAAGCGAAAAAAATAGGGTTTTA
AACATTGAAAGCGAATTGCAAAAAAGAGTGGTGGGGCAAGAAAAAGCGCTCAAAGCGATCGCTAAAGCGATTAAAAGGAA
TAAGGCCGGGCTTAGCGATAGCAACAAGCCCATAGGGAGTTTCCTCTTTTTAGGGCCAACAGGCGTGGGTAAAACCGAGA
GCGCTAAAGCTTTGGCGCAATTCTTGTTTGATAGCGATAAAAATCTTATACGAATTGACATGAGCGAATACATGGAAAAG
CACGCTATAAGCCGTCTTATTGGGGCTGCTCCTGGGTATGTGGGCTATGAAGAAGGCGGGCAATTGACCGAAGCGGTGCG
CAGAAAGCCTTATAGCGTGGTGCTGTTAGATGAAGTGGAAAAAGCCCATCCGGATGTGTTTAACCTCTTGTTGCAGGTTT
TAGATGAAGGGCATTTAACCGATAGTAAGGGCGTGAGGGTGGATTTCAAAAACACGATTTTGATTTTAACCAGCAATGTG
GCTAGCGGCGCGCTTTTAGAAGAAAATTTGAGCGAAGCCGAGAAACAAAAAGCGATTAAAGAGAGCTTGAGGCAATTCTT
CAAGCCGGAATTTTTAAACCGCCTAGATGAAATCATCTCCTTTAACGCCCTAGATAGTCATGCTATCATAAATATCGTGG
GGATACTCTTTGAAAACATTCAAAAAAAAGCGCTTGAAAGGGGCATTAATATAACCTTAGACGAAAAAGCAAAAGAATTG
ATCGCCGAAGTGGGATTTGACAGATTCTATGGCGCTAGGCCCTTAAAGCGCGCACTCTATGAAATGGTAGAAGACAAGCT
CGCTGAACTCATTTTAGAGGATAAAATTAAAGAGAATGACAGCGTGGCGTTTGTGGTAGAAAATAACGAGATTGTGCCTA
AGATTAAGTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-142)

• AAA lid domain (AAA_lid_9) (339-440)

• ATPase family associated with various cellular activities (AAA) (AAA) (201-316)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.299	100	0.442
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.997	86.098	0.396
clpE	Streptococcus mutans UA159	44.017	82.009	0.361