Detailed information    

insolico Bioinformatically predicted

Overview

Name   spo0A   Type   Regulator
Locus tag   SB24_RS17445 Genome accession   NZ_CP010406
Coordinates   3598876..3599676 (+) Length   266 a.a.
NCBI ID   WP_003153177.1    Uniprot ID   I2C7K5
Organism   Bacillus sp. Pc3     
Function   activation and repression of comK; repression of rok; repression of abrB (predicted from homology)   
Competence regulation

Genomic Context

Location: 3593876..3604676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SB24_RS17425 (SB24_17425) - 3593998..3594843 (+) 846 WP_007612503.1 TlyA family RNA methyltransferase -
  SB24_RS17430 (SB24_17430) argR 3594940..3595389 (+) 450 WP_003153173.1 transcriptional regulator ArgR -
  SB24_RS17435 (SB24_17435) recN 3595421..3597151 (+) 1731 WP_039254521.1 DNA repair protein RecN Machinery gene
  SB24_RS17440 (SB24_17440) spoIVB 3597315..3598595 (+) 1281 WP_007408360.1 SpoIVB peptidase -
  SB24_RS17445 (SB24_17445) spo0A 3598876..3599676 (+) 801 WP_003153177.1 sporulation transcription factor Spo0A Regulator
  SB24_RS17450 (SB24_17450) alr 3599825..3601006 (-) 1182 WP_012117960.1 alanine racemase -
  SB24_RS17455 (SB24_17455) - 3601182..3601394 (-) 213 WP_003153181.1 spore germination protein -
  SB24_RS17460 (SB24_17460) - 3601520..3601732 (-) 213 WP_007408362.1 spore germination protein -
  SB24_RS17465 (SB24_17465) - 3601858..3602976 (-) 1119 WP_031378952.1 NADH-dependent flavin oxidoreductase -
  SB24_RS20270 (SB24_17470) - 3603070..3603207 (-) 138 WP_014470646.1 hypothetical protein -
  SB24_RS17475 (SB24_17475) - 3603498..3604130 (-) 633 WP_007408365.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 266 a.a.        Molecular weight: 29630.11 Da        Isoelectric Point: 6.1630

>NTDB_id=136924 SB24_RS17445 WP_003153177.1 3598876..3599676(+) (spo0A) [Bacillus sp. Pc3]
MEKIKVCVADDNRELVSLLSEYIEGQDDMEVIGVAYNGQECLSLFKDKNPDVLVLDIIMPHLDGLAVLERLRESELEKQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLVGHIRQVSGNVSSVTHRAPSAQSSIIRSQPEPKRKNLDASITSII
HEIGVPAHIKGYLYLREAISMVYNDIELLGSITKVLYPDIAKKFNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVS
MTKAKPTNSEFIAMVADKLRLEHKAS

Nucleotide


Download         Length: 801 bp        

>NTDB_id=136924 SB24_RS17445 WP_003153177.1 3598876..3599676(+) (spo0A) [Bacillus sp. Pc3]
GTGGAGAAAATTAAAGTTTGTGTTGCTGATGATAATCGAGAGCTTGTAAGCCTGTTGAGTGAATATATAGAGGGACAGGA
TGATATGGAAGTGATCGGCGTTGCTTATAACGGACAGGAATGTCTTTCTTTGTTTAAAGATAAGAATCCAGATGTGCTCG
TTTTAGACATTATCATGCCGCATCTGGACGGACTTGCGGTTTTGGAGCGTCTGCGGGAATCAGAGCTCGAGAAGCAGCCG
AACGTCATCATGCTGACGGCATTCGGTCAGGAAGACGTTACGAAAAAAGCCGTCGATTTAGGCGCGTCCTATTTCATCCT
GAAGCCGTTTGATATGGAAAACCTTGTCGGCCATATTCGCCAGGTAAGCGGAAATGTCAGCAGTGTCACACACCGTGCGC
CGTCTGCGCAAAGCAGCATTATCCGCAGCCAGCCTGAGCCGAAGCGGAAAAATCTCGATGCCAGCATTACAAGCATTATC
CATGAGATCGGTGTGCCTGCCCATATCAAAGGCTATCTTTATTTGCGTGAAGCCATTTCCATGGTGTATAACGATATTGA
ACTCCTCGGCAGCATCACAAAAGTCCTTTATCCCGACATCGCCAAAAAATTCAACACGACTGCAAGCCGTGTAGAACGGG
CCATCCGGCACGCCATTGAAGTCGCATGGAGCAGGGGAAATATCGATTCCATTTCTTCACTGTTCGGATATACGGTAAGC
ATGACAAAAGCAAAGCCAACCAACTCGGAATTCATCGCGATGGTTGCTGACAAGCTGAGATTGGAGCATAAAGCTTCGTA
A

Domains

Predicted by InterproScan.

Sporulation initiation factor Spo0A C terminal (Spo0A_C)

(156-259)

Response regulator receiver domain (Response_reg)

(6-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C7K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  spo0A Bacillus subtilis subsp. subtilis str. 168

96.629

100

0.97

Multiple sequence alignment