Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SB24_RS04110 Genome accession   NZ_CP010406
Coordinates   953658..954314 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus sp. Pc3     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 948658..959314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SB24_RS04090 (SB24_04090) spxH 948897..949799 (+) 903 WP_039251990.1 protease adaptor protein SpxH -
  SB24_RS20175 (SB24_04095) - 950086..950253 (+) 168 WP_003155026.1 hypothetical protein -
  SB24_RS04100 (SB24_04100) pepF 950290..952119 (-) 1830 WP_099686889.1 oligoendopeptidase F Regulator
  SB24_RS04105 (SB24_04105) - 952347..953507 (-) 1161 WP_039251993.1 competence protein CoiA family protein -
  SB24_RS04110 (SB24_04110) mecA 953658..954314 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  SB24_RS20180 - 954297..954407 (-) 111 Protein_831 adaptor protein MecA -
  SB24_RS04115 (SB24_04115) - 954590..955246 (+) 657 WP_007409109.1 TerC family protein -
  SB24_RS04120 (SB24_04120) spx 955304..955699 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  SB24_RS04125 (SB24_04125) - 955877..956455 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  SB24_RS04130 (SB24_04130) - 956573..957760 (-) 1188 WP_015239569.1 putative glycoside hydrolase -
  SB24_RS04135 (SB24_04135) oppF 957867..958784 (-) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=136862 SB24_RS04110 WP_003155032.1 953658..954314(-) (mecA) [Bacillus sp. Pc3]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=136862 SB24_RS04110 WP_003155032.1 953658..954314(-) (mecA) [Bacillus sp. Pc3]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment