Detailed information NTG0136850

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RT44_RS13665
• Genome accession: NZ_CP010402
• Coordinates: 2691152..2692039 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GR2
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2686152..2697039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RT44_RS13630 (RT44_13655)	-	2686170..2686262 (+)	93	WP_010956583.1	hypothetical protein	-
RT44_RS13635 (RT44_13660)	-	2686370..2686867 (-)	498	WP_001065268.1	glutathione peroxidase	-
RT44_RS13640 (RT44_13665)	-	2686877..2687137 (-)	261	WP_001791974.1	hypothetical protein	-
RT44_RS13645 (RT44_13670)	-	2687519..2687632 (-)	114	Protein_2597	hypothetical protein	-
RT44_RS13655 (RT44_13680)	-	2688291..2690291 (-)	2001	WP_000776751.1	ABC transporter permease	-
RT44_RS13660 (RT44_13685)	-	2690288..2691043 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RT44_RS13665 (RT44_13690)	braS	2691152..2692039 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RT44_RS13670 (RT44_13695)	braR	2692050..2692715 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RT44_RS13675 (RT44_13700)	-	2692741..2692941 (-)	201	WP_000604727.1	hypothetical protein	-
RT44_RS13685 (RT44_13710)	-	2693139..2694563 (+)	1425	WP_000953757.1	alkaline phosphatase	-
RT44_RS15185	-	2694633..2694743 (+)	111	WP_001791296.1	hypothetical protein	-
RT44_RS13690 (RT44_13715)	-	2694846..2695301 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RT44_RS13695 (RT44_13720)	-	2695546..2696307 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=136850 RT44_RS13665 WP_000143420.1 2691152..2692039(-) (braS) [Staphylococcus aureus strain GR2]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=136850 RT44_RS13665 WP_000143420.1 2691152..2692039(-) (braS) [Staphylococcus aureus strain GR2]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993