Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SanJ4211_RS09240 Genome accession   NZ_CP012805
Coordinates   1835480..1837426 (-) Length   648 a.a.
NCBI ID   WP_003026650.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4211     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1830480..1842426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4211_RS09215 (SanJ4211_1834c) cinA 1830852..1832123 (-) 1272 WP_021002200.1 competence/damage-inducible protein A Machinery gene
  SanJ4211_RS09220 - 1832724..1833144 (+) 421 Protein_1799 EamA family transporter -
  SanJ4211_RS09225 (SanJ4211_1836c) - 1833247..1833825 (-) 579 WP_021002201.1 DNA-3-methyladenine glycosylase I -
  SanJ4211_RS09230 (SanJ4211_1837c) ruvA 1833836..1834426 (-) 591 WP_021002202.1 Holliday junction branch migration protein RuvA Machinery gene
  SanJ4211_RS09235 (SanJ4211_1838) - 1834588..1835097 (+) 510 WP_003026648.1 helix-turn-helix domain-containing protein -
  SanJ4211_RS09240 (SanJ4211_1839c) hexB 1835480..1837426 (-) 1947 WP_003026650.1 DNA mismatch repair endonuclease MutL Machinery gene
  SanJ4211_RS09245 (SanJ4211_1840) brsR 1837671..1838111 (+) 441 WP_041784066.1 LytTR family DNA-binding domain-containing protein Regulator
  SanJ4211_RS09250 (SanJ4211_1841) - 1838108..1838566 (+) 459 WP_021002204.1 DUF3021 domain-containing protein -
  SanJ4211_RS09255 (SanJ4211_1842c) hexA 1838755..1841316 (-) 2562 WP_057489838.1 DNA mismatch repair protein MutS Machinery gene
  SanJ4211_RS09260 (SanJ4211_1843c) argR 1841479..1841919 (-) 441 WP_003027809.1 arginine repressor -

Sequence

Protein


Download         Length: 648 a.a.        Molecular weight: 73161.36 Da        Isoelectric Point: 5.1688

>NTDB_id=136572 SanJ4211_RS09240 WP_003026650.1 1835480..1837426(-) (hexB) [Streptococcus anginosus strain J4211]
MSKIIELPENLANQIAAGEVIERPSSVVKELIENSIDAGATQIIVEIEEAGLRSIQVIDNGEGIEHEEVSLALRRHATSK
IKKQADLFRIRTLGFRGEALPSIASVSRLTIETATSSGAHGTLLIAQGGEVETLEPSSCPRGTKIKVEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLVNDGKEMTRTAGTGNLRQAIAGIYGLTTAKKMIEILASDLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIRIDPYLADVNVHPTKQEVRISKERELMVLISQ
AIAASLKEQDLIPDALENLAKSTINRAIKPEQTSLPLKENRLYYDKERNDFFVKPQVSEAQPSFEESARLDQQSADTDEL
NSKAASVKFAERQSPSYNQLDHPELDQASLERALDKLNGEETSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVK
YEYYREKIGDVDASQQQLLVPYIFEFPADDMLRLKQRMTLLEEVGVFLEEYGTNQFILREHPIWLKEEEIESGIYEMCDM
LLLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLIFQLSQCDNPYNCPHGRPVLVNFTKSDMGKMFRRIQENHT
SLRELGKY

Nucleotide


Download         Length: 1947 bp        

>NTDB_id=136572 SanJ4211_RS09240 WP_003026650.1 1835480..1837426(-) (hexB) [Streptococcus anginosus strain J4211]
ATGTCAAAAATTATTGAACTACCAGAAAATCTTGCTAATCAGATTGCAGCAGGTGAGGTTATTGAGCGACCTAGCAGCGT
TGTCAAGGAGTTAATAGAAAATTCTATTGATGCTGGTGCCACTCAGATTATAGTTGAGATTGAAGAAGCGGGACTCAGGA
GCATTCAAGTCATTGATAATGGTGAAGGAATTGAGCATGAGGAGGTTTCCTTGGCTTTACGGCGGCATGCTACTAGTAAA
ATCAAGAAACAAGCCGACCTTTTTCGAATTCGGACATTGGGCTTTCGGGGCGAGGCACTTCCATCCATTGCCTCTGTTTC
ACGTTTGACGATTGAAACTGCGACAAGTAGTGGTGCACATGGAACGCTTCTGATTGCGCAAGGTGGAGAAGTTGAGACTT
TAGAGCCAAGTAGCTGTCCTAGGGGCACCAAAATCAAAGTGGAAGACCTTTTTTTCAACACGCCTGCTCGCTTGAAATAT
ATGAAAAGTCAACAAGCGGAACTATCTCACATTGTAGATGTGATTAACCGTTTGAGCTTGGCTCATCCGGAGGTCGCTTT
CACTCTTGTTAATGACGGTAAAGAGATGACACGGACAGCAGGAACAGGAAATCTGCGTCAAGCAATTGCTGGCATTTATG
GACTGACAACAGCCAAAAAAATGATTGAAATTTTAGCATCTGATTTGGATTTTGAAGTATCAGGCTATATTAGTTTGCCA
GAATTAACAAGGGCTAATCGGAATTACATTACTATCCTCATCAATGGTCGCTACATCAAGAATTTCCTACTCAATCGAGC
TATTTTAGATGGATATGGTAGCAAGCTCATGGTGGGACGTTTTCCGATTGCTGTGATTGATATTCGGATTGACCCATATC
TTGCTGATGTCAATGTTCACCCGACCAAGCAAGAAGTGCGGATTTCAAAGGAGCGAGAGCTCATGGTCTTGATATCGCAA
GCTATTGCTGCAAGTTTGAAAGAGCAAGATTTGATTCCGGACGCATTAGAGAATTTAGCCAAATCAACCATTAACCGAGC
AATTAAGCCTGAACAGACCAGCCTCCCTCTCAAAGAGAACCGACTTTATTACGATAAAGAAAGAAATGACTTCTTTGTGA
AACCACAAGTGTCAGAAGCTCAACCTTCTTTTGAGGAATCTGCCCGATTAGACCAACAATCTGCTGATACAGATGAACTC
AATTCAAAAGCTGCTTCTGTCAAATTTGCAGAAAGGCAATCTCCTTCTTACAATCAACTAGATCATCCAGAGCTGGATCA
GGCGAGCTTAGAGAGAGCTTTAGATAAGCTAAATGGAGAAGAAACTTCAACGTTTCCAGAATTGGAATATTTCGGGCAAA
TGCACGGCACCTACCTTTTTGCTCAAGGAAACGGTGGCCTTTATATTATTGACCAACATGCAGCTCAAGAGCGAGTAAAG
TACGAATATTACCGTGAAAAAATCGGAGATGTAGATGCTAGTCAGCAGCAGCTTCTGGTTCCCTATATCTTTGAATTTCC
AGCTGATGATATGTTGCGTCTGAAACAACGAATGACTCTTTTAGAAGAAGTCGGTGTTTTCCTTGAAGAATACGGAACTA
ATCAATTTATTCTTCGTGAACATCCCATTTGGCTTAAGGAAGAGGAGATCGAATCAGGTATTTATGAGATGTGCGATATG
CTGCTTCTAACCAAGGAAGTCTCTATCAAGAAATATCGCGCTGAGCTGGCTATTATGATGAGTTGCAAACGCTCTATTAA
AGCCAATCACAGTTTAGATGACTATTCAGCGCGTGATTTGATTTTTCAGTTATCACAATGCGACAATCCCTACAACTGCC
CTCACGGTCGTCCCGTTTTGGTCAACTTCACCAAATCTGATATGGGAAAAATGTTCCGTCGGATTCAGGAAAACCATACT
AGCCTGAGAGAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.042

100

0.772

Multiple sequence alignment