Detailed information NTG0136361

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ACH32_RS11720
• Genome accession: NZ_CP012756
• Coordinates: 2314646..2317255 (+)
• Length: 869 a.a.
• NCBI ID: WP_060649832.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain JS395
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2309646..2322255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH32_RS11705 (ACH32_11695)	-	2310803..2311627 (-)	825	WP_001182436.1	Cof-type HAD-IIB family hydrolase	-
ACH32_RS11710 (ACH32_11700)	-	2311741..2312049 (+)	309	WP_000390575.1	metal-sulfur cluster assembly factor	-
ACH32_RS11715 (ACH32_11705)	-	2312629..2314443 (+)	1815	WP_001044232.1	acyltransferase family protein	-
ACH32_RS11720 (ACH32_11710)	clpC	2314646..2317255 (+)	2610	WP_060649832.1	ATP-dependent chaperone ClpB	Regulator
ACH32_RS11725 (ACH32_11715)	-	2317314..2318183 (-)	870	WP_001047061.1	LysR family transcriptional regulator	-
ACH32_RS11730 (ACH32_11720)	-	2318293..2319438 (+)	1146	WP_060649833.1	LeuA family protein	-
ACH32_RS11735 (ACH32_11725)	-	2319422..2320063 (+)	642	WP_000404423.1	L-threonylcarbamoyladenylate synthase	-
ACH32_RS11740 (ACH32_11730)	-	2320056..2321168 (+)	1113	WP_001037447.1	MFS transporter	-
ACH32_RS11745 (ACH32_11735)	-	2321158..2321673 (+)	516	WP_000700885.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98345.57 Da
• Isoelectric Point: 4.7219

>NTDB_id=136361 ACH32_RS11720 WP_060649832.1 2314646..2317255(+) (clpC) [Staphylococcus aureus strain JS395]
MDINKMTYAVRSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQ
YGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKKNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELD
LSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYRE
YIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATI
RTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDE
SRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETER
EKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSE
YMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIM
TSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIE
VSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE

Nucleotide

• Length: 2610 bp

>NTDB_id=136361 ACH32_RS11720 WP_060649832.1 2314646..2317255(+) (clpC) [Staphylococcus aureus strain JS395]
ATGGATATAAATAAAATGACATATGCTGTTCGAAGTGCTTTACAACAAGCAGTTGAACTAAGTCAGCAACATAAATTACA
AAATATAGAAATTGAGGCAATTTTAAGCGCTGCCTTAAATGAAAGTGAAAGCTTATATAAAAGTATTTTAGAACGAGCAA
ATATTGAGGTAGATCAATTAAACAAAGCTTATGAAGACAAACTAAACACGTATGCATCTGTAGAAGGTGACAATATACAA
TATGGTCAATATATTAGCCAACAAGCAAACCAATTGATAACTAAGGCTGAATCATACATGAAAGAATATGAAGATGAATA
TATTTCAATGGAGCATATTTTACGTTCGGCAATGGACATTGATCAAACAACAAAACATTATATAAATAATAAAGTAGAAG
TTATCAAAGAAATTATTAAAAAAGTAAGAGGGGGAAATCACGTGACATCACAAAATCCAGAAGTTAATTACGAAGCATTA
GCTAAATATGGCCGCGACTTAGTAGAAGAAGTTAGACAAGGTAAAATGGATCCTGTTATAGGAAGAGATGAAGAAATTCG
AAATACGATTCGTATTTTAAGTCGTAAAACTAAAAAAAACCCTGTGCTCATTGGTGAACCAGGTGTTGGTAAAACTGCAA
TTGTTGAAGGATTAGCGCAGCGTATAGTTAAGAAAGATGTGCCAGAATCATTATTAGATAAAACTGTTTTTGAGTTAGAT
TTAAGCGCATTAGTAGCGGGCGCTAAATATCGTGGTGAATTTGAAGAGAGATTAAAAGCAGTCCTAAAAGAAGTTAAAGA
GTCTGATGGTAGAATTATATTATTTATTGATGAAATCCATATGCTTGTAGGTGCTGGTAAAACAGATGGTGCCATGGATG
CAGGCAACATGTTAAAACCAATGTTAGCACGAGGAGAGTTACATTGTATTGGTGCAACAACTTTAAATGAATATCGAGAA
TATATTGAAAAAGATTCGGCATTAGAGCGTCGTTTCCAAAAAGTAGCAGTTAGTGAGCCTGATGTTGAAGATACAATTTC
AATTTTACGTGGTTTAAAAGAACGATATGAAGTATATCATGGTGTGCGTATTCAAGATAGAGCCTTAGTTGCTGCCGCTG
AATTGTCTGATCGTTACATCACTGATCGTTTTTTACCAGATAAAGCGATTGATTTAGTTGACCAAGCATGTGCAACAATT
CGTACGGAAATGGGATCAAATCCAACTGAATTGGATCAAGTTAATAGACGTGTCATGCAATTAGAAATTGAAGAAAGCGC
ACTTAAAAATGAATCTGACAATGCGAGCAAACAGAGATTACAAGAATTACAAGAAGAGCTTGCCAATGAAAAAGAGAAAC
AAGCAGCACTTCAATCTCGTGTAGAATCAGAAAAAGAAAAAATAGCAAATTTACAAGAAAAACGTGCGCAACTAGATGAA
AGTAGACAAGCGTTGGAAGATGCACAAACAAATAACAATTTAGAAAAAGCAGCTGAACTACAATATGGAACAATTCCTCA
ATTGGAAAAAGAACTTAGAGAATTAGAGGATAATTTCCAAGATGAGCAAGGTGAAGATACAGATCGAATGATTCGTGAAG
TTGTAACAGACGAAGAAATTGGCGATATTGTCAGCCAATGGACAGGCATACCAGTTTCAAAATTAGTTGAAACAGAACGT
GAAAAATTACTTCACTTAAGTGATATCTTGCATAAACGTGTTGTAGGTCAAGATAAAGCGGTTGACCTGGTTTCAGATGC
AGTAGTTAGAGCTAGAGCAGGTATTAAAGATCCAAACAGACCTATTGGTAGTTTCTTATTCCTAGGTCCAACTGGGGTAG
GTAAAACTGAATTAGCTAAATCATTAGCTGCATCATTATTTGATTCTGAAAAACATATGATTCGTATCGATATGAGTGAA
TATATGGAAAAACATGCAGTATCAAGATTGATAGGGGCACCTCCAGGATATATTGGACATGATGAAGGGGGTCAATTAAC
TGAAGCGGTTCGTCGTAATCCATACTCAGTTATTTTATTAGATGAGGTTGAAAAAGCGCATACTGACGTCTTTAATGTAT
TATTGCAAATTTTAGATGAAGGCCGTTTAACTGATTCTAAAGGACGTAGCGTTGATTTTAAAAATACTATTATTATTATG
ACAAGTAATATTGGATCTCAAGTTTTACTAGAAAACGTAAAAGAGACTGGTGAAATTACAGAATCAACAGAAAAAGCTGT
TATGACAAGTTTAAATGCATATTTCAAACCAGAAATTTTGAATCGTATGGATGACATCGTATTATTTAAACCTTTATCTA
TTGATGACATGAGTATGATTGTAGACAAAATATTAACGCAATTAAATATAAGATTACTAGAACAACGAATCTCAATTGAA
GTTTCTGATGATGCTAAAGCTTGGCTAGGTCAAGAGGCATATGAACCTCAATACGGTGCAAGACCATTAAAACGTTTTGT
ACAACGCCAAATTGAAACACCATTAGCACGTATGATGATTAAAGAGGGATTCCCAGAAGGTACAACTATTAAAGTTAATT
TAAATTCAGACAATAACTTAACGTTTAATGTTGAAAAAATTCATGAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-121)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-766)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (772-852)

• ATPase family associated with various cellular activities (AAA) (AAA) (202-334)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	42.657	98.734	0.421
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	39.636	100	0.4