Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GBS85147_RS00845 Genome accession   NZ_CP010319
Coordinates   143489..144244 (+) Length   251 a.a.
NCBI ID   WP_000425367.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS85147     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 138489..149244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBS85147_RS00830 (GBS85147_0168) - 138916..140466 (-) 1551 WP_000722381.1 ABC transporter substrate-binding protein/permease -
  GBS85147_RS00835 (GBS85147_0169) - 140602..142485 (+) 1884 WP_000710518.1 DUF2207 domain-containing protein -
  GBS85147_RS00840 (GBS85147_0170) - 142531..143370 (+) 840 WP_000905322.1 undecaprenyl-diphosphate phosphatase -
  GBS85147_RS00845 (GBS85147_0171) mecA 143489..144244 (+) 756 WP_000425367.1 adaptor protein MecA Regulator
  GBS85147_RS00850 (GBS85147_0172) - 144246..145406 (+) 1161 WP_000612110.1 glycosyltransferase family 4 protein -
  GBS85147_RS00855 (GBS85147_0173) sufC 145569..146339 (+) 771 WP_000114503.1 Fe-S cluster assembly ATPase SufC -
  GBS85147_RS00860 (GBS85147_0174) sufD 146376..147638 (+) 1263 WP_000031277.1 Fe-S cluster assembly protein SufD -
  GBS85147_RS00865 (GBS85147_0175) - 147640..148872 (+) 1233 WP_000173343.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 29040.88 Da        Isoelectric Point: 4.2118

>NTDB_id=136343 GBS85147_RS00845 WP_000425367.1 143489..144244(+) (mecA) [Streptococcus agalactiae strain GBS85147]
MEMKQISETTLKITISMEDLEDRGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKNSGMLSFRVTPKKDRIDVFVTKSEL
SKDLNLEELADLGDISKMSPEDFFKTLEQSMLEKGDTDAHAKLAEIENMMDKATQEVVEENVSEEQPEKEVETIGYVHYV
FDFDNIEAVVRFSQTIDFPIEASELYKNGKGYHMTILLDLENQPSYFANLMYARMLEHANVGTKTRAYLKEHSIQLIHDD
AISKLQMIEMG

Nucleotide


Download         Length: 756 bp        

>NTDB_id=136343 GBS85147_RS00845 WP_000425367.1 143489..144244(+) (mecA) [Streptococcus agalactiae strain GBS85147]
ATGGAAATGAAACAAATCAGTGAAACAACACTGAAAATTACAATTAGTATGGAAGATTTAGAAGATCGTGGTATGGAGCT
GAAAGATTTCCTAATCCCTCAGGAGAAGACTGAGGAATTTTTCTATTCTGTCATGGATGAATTAGACTTGCCAGACAACT
TTAAAAATAGTGGTATGTTAAGTTTTCGAGTAACACCTAAAAAAGATCGCATTGATGTTTTTGTTACAAAGTCTGAATTA
AGTAAAGATTTAAATTTAGAAGAATTAGCAGATTTGGGTGACATTTCAAAAATGTCTCCAGAAGACTTTTTTAAAACATT
GGAACAATCGATGTTGGAAAAAGGGGATACGGATGCTCATGCCAAATTAGCAGAAATTGAAAATATGATGGATAAAGCAA
CTCAAGAAGTAGTTGAGGAAAATGTTTCTGAAGAACAACCTGAAAAGGAAGTAGAAACGATTGGATATGTTCACTATGTC
TTTGATTTTGATAATATTGAAGCTGTAGTTCGATTTTCACAAACGATTGATTTTCCAATAGAAGCTTCTGAACTCTATAA
AAATGGTAAAGGCTATCATATGACAATTTTGCTAGACTTGGAAAACCAACCAAGCTACTTTGCTAATTTGATGTATGCTC
GAATGCTTGAACATGCTAATGTGGGCACAAAAACACGAGCTTACTTGAAAGAGCATAGTATTCAATTGATTCATGATGAT
GCTATTTCAAAATTACAAATGATTGAGATGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.339

98.805

0.665
  mecA Streptococcus thermophilus LMD-9

60.558

100

0.606
  mecA Streptococcus thermophilus LMG 18311

59.761

100

0.598
  mecA Streptococcus pneumoniae Rx1

47.012

100

0.47
  mecA Streptococcus pneumoniae D39

47.012

100

0.47
  mecA Streptococcus pneumoniae R6

47.012

100

0.47
  mecA Streptococcus pneumoniae TIGR4

47.012

100

0.47

Multiple sequence alignment