Detailed information NTG0136338

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: ACH32_RS06160
• Genome accession: NZ_CP012756
• Coordinates: 1162903..1165011 (+)
• Length: 702 a.a.
• NCBI ID: WP_060649704.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain JS395
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1157903..1170011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACH32_RS06135 (ACH32_06130)	-	1157972..1158190 (+)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-
ACH32_RS06140 (ACH32_06135)	-	1158578..1159009 (+)	432	WP_000875614.1	CHAP domain-containing protein	-
ACH32_RS06145 (ACH32_06140)	-	1159148..1160428 (-)	1281	WP_001191002.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACH32_RS06150 (ACH32_06145)	-	1160683..1161849 (+)	1167	WP_000151984.1	hydroxymethylglutaryl-CoA synthase	-
ACH32_RS06155 (ACH32_06150)	-	1162019..1162540 (-)	522	WP_000262597.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
ACH32_RS06160 (ACH32_06155)	clpE	1162903..1165011 (+)	2109	WP_060649704.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
ACH32_RS06165 (ACH32_06160)	-	1165078..1165248 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
ACH32_RS06170 (ACH32_06165)	feoB	1165261..1167255 (-)	1995	WP_000432904.1	ferrous iron transport protein B	-
ACH32_RS06175 (ACH32_06170)	-	1167267..1167494 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78375.73 Da
• Isoelectric Point: 4.6037

>NTDB_id=136338 ACH32_RS06160 WP_060649704.1 1162903..1165011(+) (clpE) [Staphylococcus aureus strain JS395]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELSQFTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNDNY
LEQIGRNLTQEARDRLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPDDVLKSCVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIVICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=136338 ACH32_RS06160 WP_060649704.1 1162903..1165011(+) (clpE) [Staphylococcus aureus strain JS395]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTATCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAATGACAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACAGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAATGTACCTGCAGCCATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGTGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGT
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCTGACAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGACCA
AGCTGTAGAGATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGATTCGATGACGGCAACCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCGTTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AATCACTTCAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACACTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.377	92.308	0.437
clpE	Streptococcus pneumoniae Rx1	47.164	87.892	0.415
clpE	Streptococcus pneumoniae D39	47.164	87.892	0.415
clpE	Streptococcus pneumoniae R6	47.164	87.892	0.415
clpE	Streptococcus pneumoniae TIGR4	47.164	87.892	0.415
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	44.479	92.877	0.413
clpC	Streptococcus thermophilus LMD-9	43.76	90.171	0.395
clpC	Streptococcus thermophilus LMG 18311	43.444	90.171	0.392
clpC	Streptococcus pneumoniae TIGR4	42.766	89.601	0.383
clpC	Streptococcus pneumoniae Rx1	42.766	89.601	0.383
clpC	Streptococcus pneumoniae D39	42.766	89.601	0.383
clpC	Streptococcus mutans UA159	43.252	87.607	0.379
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.832	92.45	0.377