Detailed information NTG0136174

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: AN924_RS05755
• Genome accession: NZ_CP012731
• Coordinates: 1130717..1133257 (+)
• Length: 846 a.a.
• NCBI ID: WP_009910996.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 90-1330
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1125717..1138257

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AN924_RS05730 (AN924_11990)	-	1126092..1126283 (-)	192	WP_024376023.1	hypothetical protein	-
AN924_RS05735 (AN924_12000)	-	1126412..1126936 (+)	525	WP_024384267.1	membrane protein	-
AN924_RS11225 (AN924_12010)	-	1126986..1128287 (-)	1302	WP_157071316.1	SH3 domain-containing protein	-
AN924_RS05745 (AN924_12020)	argS	1128467..1130155 (-)	1689	WP_044689861.1	arginine--tRNA ligase	-
AN924_RS05750 (AN924_12030)	argR	1130262..1130702 (+)	441	WP_002937036.1	arginine repressor	-
AN924_RS05755 (AN924_12040)	hexA	1130717..1133257 (+)	2541	WP_009910996.1	DNA mismatch repair protein MutS	Machinery gene
AN924_RS05760 (AN924_12050)	-	1133510..1133683 (+)	174	WP_009910995.1	hypothetical protein	-
AN924_RS05765 (AN924_12060)	-	1133797..1134483 (+)	687	WP_013730663.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
AN924_RS05770 (AN924_12080)	-	1134516..1135367 (+)	852	WP_013730662.1	amino acid ABC transporter substrate-binding protein	-
AN924_RS05775 (AN924_12090)	-	1135553..1136356 (+)	804	WP_014637221.1	amino acid ABC transporter permease	-
AN924_RS05780 (AN924_12100)	-	1136356..1137099 (+)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95044.55 Da
• Isoelectric Point: 4.8211

>NTDB_id=136174 AN924_RS05755 WP_009910996.1 1130717..1133257(+) (hexA) [Streptococcus suis strain 90-1330]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVALDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAIVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVIREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTTPAPIVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=136174 AN924_RS05755 WP_009910996.1 1130717..1133257(+) (hexA) [Streptococcus suis strain 90-1330]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCGCAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCATGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGCTTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCAAACCAGATGAACCTCCTACTCTCTTTTGAAGATGAGGTGACAGAGGATGTCCAATTGATTGATAACTCCTTGACAG
ATTTGGAAAAGGCTGCGGCGGGCAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTATCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTTGAAGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCTAGCCGGGTATCTTTTGGAAAAAC
CATGCCAAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATTTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACGGGCTTTGATGAAACGCTGGATCAGTATCGTCTGGTCAT
TCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCTAAGGAGCGTGAAGCGTCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTTACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACTCGTATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCAGTCCGTCTGGCGACAGATCGGTCACTCATCCTCTTTGATGAGTTGGGGCGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGAGCCAAGACTCTCTTTGCTACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGTCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCGGACAGGATTTTGCAGACGCTTGAAAACCAAGCTCCTACTGCACCAACTACCCCAGCTCCGATAGTCGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCTTCTCACCCAGTCCTCGATGAACTGGCAAAACTGGATAT
CTACAATATGACCCCTATGGAAGTCATGATGGCAGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.877	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	37.747	100	0.384