Detailed information NTG0136044

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RM27_RS13040
• Genome accession: NZ_CP010299
• Coordinates: 2769080..2769967 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ATCC BAA1680
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764080..2774967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RM27_RS15245 (RM27_14185)	-	2764099..2764191 (+)	93	WP_010956583.1	hypothetical protein	-
RM27_RS13025 (RM27_14190)	-	2764299..2764796 (-)	498	WP_001065268.1	glutathione peroxidase	-
RM27_RS15250 (RM27_14195)	-	2764806..2765066 (-)	261	WP_001789910.1	hypothetical protein	-
RM27_RS15260 (RM27_14200)	-	2765448..2765561 (-)	114	WP_001791776.1	hypothetical protein	-
RM27_RS13030 (RM27_14210)	-	2766220..2768220 (-)	2001	WP_000776751.1	ABC transporter permease	-
RM27_RS13035 (RM27_14215)	-	2768217..2768972 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RM27_RS13040 (RM27_14220)	braS	2769080..2769967 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RM27_RS13045 (RM27_14225)	braR	2769978..2770643 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RM27_RS13050 (RM27_14230)	-	2770669..2770869 (-)	201	WP_000604728.1	hypothetical protein	-
RM27_RS13055 (RM27_14240)	-	2771067..2772491 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RM27_RS15735	-	2772551..2772652 (-)	102	WP_000731972.1	SE2200 family small protein	-
RM27_RS13060 (RM27_14245)	-	2772774..2773229 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RM27_RS13065 (RM27_14250)	-	2773474..2774235 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=136044 RM27_RS13040 WP_000143419.1 2769080..2769967(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=136044 RM27_RS13040 WP_000143419.1 2769080..2769967(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997