Detailed information NTG0135955

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QT38_RS09450
• Genome accession: NZ_CP010297
• Coordinates: 2026204..2027247 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain ATCC BAA1680
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021204..2032247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QT38_RS09420 (QT38_10145)	-	2021622..2022878 (-)	1257	WP_001795438.1	aminopeptidase	-
QT38_RS09425 (QT38_10150)	-	2022881..2023081 (-)	201	WP_000180461.1	DUF1128 family protein	-
QT38_RS09430 (QT38_10155)	-	2023228..2023692 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QT38_RS09435 (QT38_10160)	-	2023699..2023974 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QT38_RS09440 (QT38_10165)	-	2024252..2025469 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QT38_RS09445 (QT38_10170)	vraR	2025585..2026214 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
QT38_RS09450 (QT38_10175)	vraS	2026204..2027247 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QT38_RS09455 (QT38_10180)	liaF	2027244..2027945 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QT38_RS09460 (QT38_10185)	-	2027960..2028346 (-)	387	WP_001110179.1	hypothetical protein	-
QT38_RS09465 (QT38_10190)	map	2028563..2029321 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QT38_RS09470 (QT38_10200)	-	2029849..2030835 (+)	987	WP_000999713.1	FUSC family protein	-
QT38_RS09485 (QT38_10210)	-	2031384..2031797 (-)	414	WP_001549145.1	hypothetical protein	-
QT38_RS14655 (QT38_10215)	-	2031826..2031936 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=135955 QT38_RS09450 WP_001017131.1 2026204..2027247(-) (vraS) [Staphylococcus aureus strain ATCC BAA1680]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=135955 QT38_RS09450 WP_001017131.1 2026204..2027247(-) (vraS) [Staphylococcus aureus strain ATCC BAA1680]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1