Detailed information NTG0135918

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RM30_RS13025
• Genome accession: NZ_CP010296
• Coordinates: 2769078..2769965 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ATCC BAA1680
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764078..2774965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RM30_RS15245 (RM30_14175)	-	2764097..2764189 (+)	93	WP_010956583.1	hypothetical protein	-
RM30_RS13010 (RM30_14180)	-	2764297..2764794 (-)	498	WP_001065268.1	glutathione peroxidase	-
RM30_RS15250 (RM30_14185)	-	2764804..2765064 (-)	261	WP_001789910.1	hypothetical protein	-
RM30_RS15260 (RM30_14190)	-	2765446..2765559 (-)	114	WP_001791776.1	hypothetical protein	-
RM30_RS13015 (RM30_14200)	-	2766218..2768218 (-)	2001	WP_000776751.1	ABC transporter permease	-
RM30_RS13020 (RM30_14205)	-	2768215..2768970 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RM30_RS13025 (RM30_14210)	braS	2769078..2769965 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RM30_RS13030 (RM30_14215)	braR	2769976..2770641 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RM30_RS13035 (RM30_14220)	-	2770667..2770867 (-)	201	WP_000604728.1	hypothetical protein	-
RM30_RS13040 (RM30_14230)	-	2771065..2772489 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RM30_RS15735	-	2772549..2772650 (-)	102	WP_000731972.1	SE2200 family small protein	-
RM30_RS13045 (RM30_14235)	-	2772772..2773227 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RM30_RS13050 (RM30_14240)	-	2773472..2774233 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=135918 RM30_RS13025 WP_000143419.1 2769078..2769965(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=135918 RM30_RS13025 WP_000143419.1 2769078..2769965(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997