Detailed information NTG0135876

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RM29_RS13040
• Genome accession: NZ_CP010295
• Coordinates: 2769067..2769954 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain ATCC BAA1680
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764067..2774954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RM29_RS15240 (RM29_14185)	-	2764086..2764178 (+)	93	WP_010956583.1	hypothetical protein	-
RM29_RS13025 (RM29_14190)	-	2764286..2764783 (-)	498	WP_001065268.1	glutathione peroxidase	-
RM29_RS15245 (RM29_14195)	-	2764793..2765053 (-)	261	WP_001789910.1	hypothetical protein	-
RM29_RS15255 (RM29_14200)	-	2765435..2765548 (-)	114	WP_001791776.1	hypothetical protein	-
RM29_RS13030 (RM29_14210)	-	2766207..2768207 (-)	2001	WP_000776751.1	ABC transporter permease	-
RM29_RS13035 (RM29_14215)	-	2768204..2768959 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RM29_RS13040 (RM29_14220)	braS	2769067..2769954 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RM29_RS13045 (RM29_14225)	braR	2769965..2770630 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RM29_RS13050 (RM29_14230)	-	2770656..2770856 (-)	201	WP_000604728.1	hypothetical protein	-
RM29_RS13055 (RM29_14240)	-	2771054..2772478 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RM29_RS15735	-	2772538..2772639 (-)	102	WP_000731972.1	SE2200 family small protein	-
RM29_RS13060 (RM29_14245)	-	2772761..2773216 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RM29_RS13065 (RM29_14250)	-	2773461..2774222 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=135876 RM29_RS13040 WP_000143419.1 2769067..2769954(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=135876 RM29_RS13040 WP_000143419.1 2769067..2769954(-) (braS) [Staphylococcus aureus strain ATCC BAA1680]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997