Detailed information NTG0135356

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: RN80_RS03605
• Genome accession: NZ_CP012646
• Coordinates: 698368..700473 (+)
• Length: 701 a.a.
• NCBI ID: WP_060627555.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain KCOM 1350 (= ChDC B183)
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 693368..705473

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RN80_RS03585 (RN80_03595)	rsmH	693513..694463 (+)	951	WP_060627549.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
RN80_RS03590 (RN80_03600)	ftsL	694473..694790 (+)	318	WP_000227824.1	cell division protein FtsL	-
RN80_RS03595 (RN80_03605)	pbp2X	694794..697046 (+)	2253	WP_060627551.1	penicillin-binding protein PBP2X	-
RN80_RS03600 (RN80_03610)	mraY	697048..698028 (+)	981	WP_060627553.1	phospho-N-acetylmuramoyl-pentapeptide- transferase	-
RN80_RS03605 (RN80_03615)	clpC	698368..700473 (+)	2106	WP_060627555.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
RN80_RS03610 (RN80_03620)	-	700537..701019 (-)	483	WP_000032562.1	S-ribosylhomocysteine lyase	-
RN80_RS03615 (RN80_03625)	-	701114..702598 (-)	1485	WP_060627557.1	DUF1846 domain-containing protein	-
RN80_RS03620 (RN80_03630)	-	702751..704361 (+)	1611	WP_060627559.1	glycoside hydrolase family 13 protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77492.25 Da
• Isoelectric Point: 4.7893

>NTDB_id=135356 RN80_RS03605 WP_060627555.1 698368..700473(+) (clpC) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAETDGQMKQQSSGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIEAEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
TDIERLKDMGHRLQTKVIGQDKAVEAVAKAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLAVS
QAAKDYITEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDHLDAKHLEADMEDGGLVIREKA

Nucleotide

• Length: 2106 bp

>NTDB_id=135356 RN80_RS03605 WP_060627555.1 698368..700473(+) (clpC) [Streptococcus mitis strain KCOM 1350 (= ChDC B183)]
ATGAACAACAACTTTAATAATTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGCCGTTACTTGATTAATGGACGTGAAGTCACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAAACTGATGGACAAATGAAACAACAGTCTTCAGGTATGAAACAAGATGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACTGCAGAAGCGCGTGAGGGCAAGTTGGATCCTGTCATCGGACGAAACAAGGAAATTCAAGAAACATCTGA
AATTCTTTCTCGTCGCACCAAGAACAATCCTGTTTTAGTTGGAGACGCAGGTGTTGGTAAAACTGCAGTAGTAGAAGGAT
TGGCCCAAGCTATCGTGAACGGTGACGTTCCAGCTGCCATTAAGAATAAAGAAATTATTTCCATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGCGGTAGCTTTGAAGAAAACGTTCAAAACTTAGTCAATGAAGTAAAAGAAGCAGGGAATAT
CATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACAGGTGATGGTCAAGGATCTAAAGGTCTTGCTG
ATATCTTGAAACCAGCTCTTTCTCGTGGAGAATTGACAGTGATTGGCGCAACAACTCAAGACGAATACCGTAATACTATC
TTGAAAAATGCAGCCCTTGCTCGTCGTTTCAACGAAGTCAAGGTCAATGCTCCTTCAGCAGAGGATACTTTTAAAATCCT
TCAAGGAATTCGTGATCTCTATCAACAACACCACAATGTTATTTTGCCAGATGAAGTCTTAAAAGCAGCAGTGGATTATT
CTGTTCAGTATATTCCTCAACGTAGTTTGCCAGATAAGGCTATCGACCTTGTCGATGTTACGGCGGCTCACTTGGCAGCT
CAGCATCCAGTAACAGATGTTCATGCTGTTGAACGTGAAATTGAGGCAGAAAAAGACAAGCAAGAAAAAGCAGTTGAGGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCATACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTAGAACGTATGACGGGTATTCCAGTATCTCAAATGGGGGCT
ACGGACATCGAACGTTTGAAAGATATGGGTCATCGTTTGCAGACGAAAGTTATTGGTCAAGATAAGGCCGTTGAAGCAGT
AGCAAAAGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGTCCTA
CTGGTGTTGGTAAGACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGAACGAAAGATGCTATCATCCGTTTGGAC
ATGTCAGAATACAGCGACCGCACAGCCGTATCTAAATTGATTGGTACAACTGCAGGTTATGTTGGTTACGATGACAACAA
CAATACCTTGACAGAACGCGTCCGTCGCAATCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAG
TCATCACCCTTCTCCTTCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTCAACTTCAAGAATACG
GTGATTATCGCAACTTCAAACGCAGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCGGACAAACCAGAATTGATGGA
CCGTTTGAAACCATTCTTCCGTCCAGAGTTCCTCAACCGCTTTAACGCAGTCATTGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAAATTGTGGACTTGATGCTGGCTGAAGTCAACCAAACCTTGGCTAAGAAAGACATTGATTTAGCAGTTAGT
CAAGCGGCTAAAGACTATATCACAGAAGAAGGCTACGATGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACA
ACAAATCCGTGACAAAGTCACAGACTTCCACTTGGATCACCTAGATGCCAAACACCTAGAAGCAGATATGGAAGACGGTG
GTTTGGTTATTCGTGAGAAAGCTTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• AAA lid domain (AAA_lid_9) (259-354)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.795	100	0.479
clpE	Streptococcus mutans UA159	50.39	91.441	0.461
clpE	Streptococcus pneumoniae TIGR4	48.983	91.155	0.447
clpE	Streptococcus pneumoniae Rx1	48.983	91.155	0.447
clpE	Streptococcus pneumoniae D39	48.983	91.155	0.447
clpE	Streptococcus pneumoniae R6	48.983	91.155	0.447
clpC	Bacillus subtilis subsp. subtilis str. 168	44.577	96.006	0.428
clpC	Streptococcus pneumoniae Rx1	42.925	89.729	0.385
clpC	Streptococcus pneumoniae D39	42.925	89.729	0.385
clpC	Streptococcus pneumoniae TIGR4	42.766	89.729	0.384
clpC	Streptococcus thermophilus LMD-9	43.226	88.445	0.382
clpC	Streptococcus thermophilus LMG 18311	43.065	88.445	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.788	88.017	0.377
clpC	Streptococcus mutans UA159	41.909	88.16	0.369