Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   RG63_RS12190 Genome accession   NZ_CP010221
Coordinates   2317213..2317842 (-) Length   209 a.a.
NCBI ID   WP_000839153.1    Uniprot ID   A0A9Q6Y251
Organism   Escherichia coli strain M19     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2306135..2329016 2317213..2317842 within 0


Gene organization within MGE regions


Location: 2306135..2329016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RG63_RS12125 (RG63_11575) - 2306135..2307154 (+) 1020 WP_073519722.1 tyrosine-type recombinase/integrase -
  RG63_RS12130 (RG63_11580) yccA 2307562..2308221 (+) 660 WP_000375136.1 FtsH protease modulator YccA -
  RG63_RS12135 (RG63_11585) tusE 2308312..2308641 (+) 330 WP_000904442.1 sulfurtransferase TusE -
  RG63_RS12140 (RG63_11590) yccX 2308638..2308916 (-) 279 WP_000048252.1 acylphosphatase -
  RG63_RS12145 (RG63_11595) rlmI 2309011..2310201 (+) 1191 WP_000116297.1 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI -
  RG63_RS12150 (RG63_11600) hspQ 2310259..2310576 (+) 318 WP_001358373.1 heat shock protein HspQ -
  RG63_RS12155 (RG63_11605) yccU 2310621..2311034 (-) 414 WP_001301418.1 CoA-binding protein -
  RG63_RS12165 (RG63_11615) yccT 2311207..2311869 (+) 663 WP_000847783.1 DUF2057 family protein -
  RG63_RS12170 (RG63_11620) mgsA 2311965..2312423 (+) 459 WP_000424181.1 methylglyoxal synthase -
  RG63_RS12175 (RG63_11625) helD 2312455..2314509 (-) 2055 WP_000420533.1 DNA helicase IV -
  RG63_RS12180 (RG63_11630) yccF 2314632..2315078 (+) 447 WP_001261231.1 YccF domain-containing protein -
  RG63_RS12185 (RG63_11635) yccS 2315088..2317250 (+) 2163 WP_000875044.1 YccS family putative transporter -
  RG63_RS12190 (RG63_11640) sxy/tfoX 2317213..2317842 (-) 630 WP_000839153.1 CRP-S regulon transcriptional coactivator Sxy Regulator
  RG63_RS12195 (RG63_11645) sulA 2318061..2318570 (+) 510 WP_000288710.1 SOS-induced cell division inhibitor SulA -
  RG63_RS12205 (RG63_11655) ompA 2318927..2319967 (+) 1041 WP_000750416.1 porin OmpA -
  RG63_RS12210 (RG63_11660) matP 2320043..2320495 (-) 453 WP_000877161.1 macrodomain Ter protein MatP -
  RG63_RS12215 (RG63_11665) ycbZ 2320681..2322441 (+) 1761 WP_000156526.1 Lon protease family protein -
  RG63_RS12220 (RG63_11670) fabA 2322510..2323028 (+) 519 WP_000227927.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  RG63_RS12225 (RG63_11675) rmf 2323098..2323265 (-) 168 WP_000828648.1 ribosome modulation factor -
  RG63_RS12230 (RG63_11680) pqiC 2323521..2324084 (-) 564 WP_000759123.1 membrane integrity-associated transporter subunit PqiC -
  RG63_RS12235 (RG63_11685) pqiB 2324081..2325721 (-) 1641 WP_000445533.1 intermembrane transport protein PqiB -
  RG63_RS12240 (RG63_11690) pqiA 2325726..2326979 (-) 1254 WP_000333176.1 membrane integrity-associated transporter subunit PqiA -
  RG63_RS12245 (RG63_11695) uup 2327109..2329016 (-) 1908 WP_000053089.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 24147.02 Da        Isoelectric Point: 9.2180

>NTDB_id=135106 RG63_RS12190 WP_000839153.1 2317213..2317842(-) (sxy/tfoX) [Escherichia coli strain M19]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=135106 RG63_RS12190 WP_000839153.1 2317213..2317842(-) (sxy/tfoX) [Escherichia coli strain M19]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGCAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(14-106)

TfoX C-terminal domain (TfoX_C)

(116-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

100

100

1

Multiple sequence alignment