Detailed information NTG0133771

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AMM49_RS06555
• Genome accession: NZ_CP012480
• Coordinates: 1291297..1293405 (+)
• Length: 702 a.a.
• NCBI ID: WP_000002813.1
• Uniprot ID: Q8DZ19
• Organism: Streptococcus agalactiae strain NGBS128
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1286297..1298405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AMM49_RS06530 (AMM49_06515)	-	1286575..1287771 (-)	1197	WP_000626555.1	protein kinase family protein	-
AMM49_RS06535 (AMM49_06520)	-	1287829..1288638 (-)	810	WP_000264509.1	Eco47II family restriction endonuclease	-
AMM49_RS06540 (AMM49_06525)	-	1288639..1289640 (-)	1002	WP_000835391.1	DNA cytosine methyltransferase	-
AMM49_RS06545 (AMM49_06530)	rplL	1289935..1290300 (-)	366	WP_001196973.1	50S ribosomal protein L7/L12	-
AMM49_RS06550 (AMM49_06535)	rplJ	1290364..1290864 (-)	501	WP_001287287.1	50S ribosomal protein L10	-
AMM49_RS06555 (AMM49_06540)	clpC	1291297..1293405 (+)	2109	WP_000002813.1	AAA family ATPase	Regulator
AMM49_RS06560 (AMM49_06545)	mmuM	1293498..1294442 (-)	945	WP_000532340.1	homocysteine S-methyltransferase	-
AMM49_RS06565 (AMM49_06550)	-	1294447..1295823 (-)	1377	WP_000427485.1	amino acid permease	-
AMM49_RS06570 (AMM49_06555)	-	1295953..1296603 (-)	651	WP_000120093.1	HXXEE domain-containing protein	-
AMM49_RS11360 (AMM49_06560)	-	1296761..1297171 (-)	411	WP_001191111.1	HXXEE domain-containing protein	-
AMM49_RS06580 (AMM49_06565)	-	1297356..1297904 (+)	549	WP_000140663.1	TetR/AcrR family transcriptional regulator	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77720.49 Da
• Isoelectric Point: 4.8125

>NTDB_id=133771 AMM49_RS06555 WP_000002813.1 1291297..1293405(+) (clpC) [Streptococcus agalactiae strain NGBS128]
MANNNFYNRDPFGNMDDIFNSLMGNMGGYNSENKRYLINGREVTPEEFSQYRQTGKLPGQELNNQNTPTNQVSADSVLTK
LGTNLTDQARQHLLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIINGDVPAAIKNKEIISIDIS
SLEAGTQYRGSFEENIQNIIKEVKETGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAQDTFNILMGIRNLYEQHHNVVLPDSVLKAAVDLSIQYIPQRSLPDKAIDLIDMTAAHL
AAQHPVTDLKSLEKEIAEQRDKQEKAVNTEDFEEALKVKTRIEELQNQIDNHTEGQKVTATINDIAMSIERLTGVPVSNM
GASDIERLKELGNRLKGKVIGQNDAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAFDMFGSKDAIVR
LDMSEYNDRTAVSKLIGATAGYVGYDDNSNTLTERIRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFK
NTVIIATSNAGFGNEAFTGDSDKDLKIMERISPYFRPEFLNRFNGVIEFSHLSKDDLSEIVDLMLDEVNQTIGKKGIDLV
VDENVKSHLIELGYDEAMGVRPLRRVIEQEIRDRITDYYLDHTDVKHLKANLQDGQIVISER

Nucleotide

• Length: 2109 bp

>NTDB_id=133771 AMM49_RS06555 WP_000002813.1 1291297..1293405(+) (clpC) [Streptococcus agalactiae strain NGBS128]
ATGGCAAATAATAATTTTTATAATCGTGACCCTTTTGGAAATATGGATGATATTTTTAATTCTCTAATGGGAAATATGGG
GGGCTATAACAGTGAGAATAAGCGATACTTAATCAATGGACGGGAAGTTACTCCTGAAGAATTCAGTCAATATCGTCAAA
CTGGAAAACTCCCCGGTCAAGAGCTAAATAACCAAAACACTCCTACAAACCAAGTCTCTGCAGATAGTGTTTTGACTAAA
TTAGGAACTAATTTAACCGATCAAGCACGTCAGCATTTGCTAGATCCAGTTATTGGACGAAACAAAGAAATTCAGGAAAC
TGCAGAAATTCTAGCTCGTCGTACTAAAAATAATCCTGTTCTGGTTGGTGATGCAGGTGTTGGTAAAACAGCTGTTATTG
AAGGTTTGGCACAAGCAATTATAAATGGTGATGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCGATAGATATTTCT
AGCCTTGAAGCTGGCACCCAATATAGGGGTAGTTTTGAAGAAAATATTCAAAATATCATAAAAGAAGTTAAGGAAACAGG
AAATATTATTCTCTTCTTTGATGAAATACACCAAATATTAGGAGCCGGTTCAACTGGTGGTGATAGTGGCTCTAAGGGGC
TCGCAGATATACTTAAGCCTGCACTTTCACGTGGTGAGTTAACGGTTATAGGTGCAACTACTCAAGATGAATATCGTAAC
ACCATTCTCAAGAATGCTGCCTTAGCACGTCGCTTTAACGAAGTTAAAGTCAATGCACCTTCTGCACAAGATACTTTCAA
TATCCTTATGGGGATAAGAAACCTCTATGAGCAACATCATAATGTTGTTTTACCTGACTCTGTTTTGAAAGCAGCTGTAG
ATTTATCTATTCAATACATCCCACAAAGAAGTCTCCCTGATAAAGCAATTGACCTTATTGATATGACTGCTGCACACCTA
GCTGCGCAACATCCCGTAACTGACCTTAAATCCTTAGAAAAAGAAATCGCTGAGCAAAGAGACAAGCAAGAAAAAGCTGT
CAATACTGAAGATTTTGAAGAAGCTCTTAAGGTCAAGACACGCATTGAAGAGTTACAAAACCAGATTGATAATCATACCG
AAGGACAAAAAGTCACTGCAACTATCAACGATATCGCTATGTCAATTGAGCGTCTAACTGGAGTTCCTGTATCAAATATG
GGTGCTAGTGATATTGAACGCTTAAAAGAACTTGGCAATCGTCTAAAAGGTAAAGTCATTGGTCAAAATGATGCTGTTGA
GGCAGTTGCGAGAGCTATTCGCCGAAATCGTGCTGGTTTCGATGATGGTAATCGTCCGATTGGTAGCTTTCTATTTGTTG
GACCAACTGGAGTTGGTAAAACCGAGCTAGCAAAGCAATTAGCTTTTGATATGTTCGGATCAAAGGATGCTATCGTTAGA
CTTGATATGTCTGAATATAATGATCGTACAGCAGTTTCTAAGCTAATTGGAGCGACTGCTGGTTACGTTGGTTATGACGA
CAATAGTAATACACTAACAGAACGTATCCGTCGAAATCCTTATTCTATTGTTCTTCTTGATGAAATCGAAAAAGCTGACC
CGCAAGTTATCACGCTTCTCCTTCAAGTTCTAGATGATGGCCGTTTAACTGATGGTCAAGGAAACACTATTAACTTTAAA
AATACTGTTATCATTGCAACCTCAAATGCAGGTTTTGGAAACGAAGCATTTACAGGTGACAGCGATAAAGACTTGAAAAT
TATGGAACGAATTTCTCCATATTTCCGTCCAGAATTTCTAAATCGTTTCAATGGTGTTATTGAATTCTCTCACCTAAGCA
AAGATGACTTAAGCGAAATTGTAGATTTGATGCTTGATGAAGTTAACCAAACAATTGGCAAAAAAGGAATTGACCTTGTG
GTAGATGAAAATGTTAAATCACACTTAATTGAACTGGGTTATGACGAAGCAATGGGAGTACGTCCATTGCGCCGTGTCAT
CGAGCAAGAAATTCGAGATCGCATCACAGACTACTATCTCGATCATACAGACGTTAAACACCTAAAAGCTAATTTGCAAG
ATGGCCAAATCGTCATTTCTGAAAGATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (261-358)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-683)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-604)

3D structure

• AlphaFold DB: Q8DZ19

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.346	99.288	0.47
clpE	Streptococcus pneumoniae Rx1	48.983	91.026	0.446
clpE	Streptococcus pneumoniae D39	48.983	91.026	0.446
clpE	Streptococcus pneumoniae R6	48.983	91.026	0.446
clpE	Streptococcus pneumoniae TIGR4	48.983	91.026	0.446
clpE	Streptococcus mutans UA159	49.367	90.028	0.444
clpC	Bacillus subtilis subsp. subtilis str. 168	44.328	95.442	0.423
clpC	Streptococcus pneumoniae Rx1	42.994	89.459	0.385
clpC	Streptococcus pneumoniae D39	42.994	89.459	0.385
clpC	Streptococcus pneumoniae TIGR4	42.994	89.459	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.022	90.171	0.379
clpC	Streptococcus thermophilus LMD-9	42.857	86.752	0.372
clpC	Streptococcus thermophilus LMG 18311	42.693	86.752	0.37
clpC	Streptococcus mutans UA159	40.498	91.453	0.37