Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   AMM49_RS06250 Genome accession   NZ_CP012480
Coordinates   1222958..1223440 (-) Length   160 a.a.
NCBI ID   WP_000163512.1    Uniprot ID   Q8DZB3
Organism   Streptococcus agalactiae strain NGBS128     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1217958..1228440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AMM49_RS06230 (AMM49_06215) alsS 1218217..1219899 (-) 1683 WP_000140341.1 acetolactate synthase AlsS -
  AMM49_RS06235 (AMM49_06220) - 1220009..1221235 (-) 1227 WP_000934868.1 tetratricopeptide repeat protein -
  AMM49_RS06240 (AMM49_06225) - 1221225..1222415 (-) 1191 WP_001075588.1 AI-2E family transporter -
  AMM49_RS06245 (AMM49_06230) - 1222507..1222968 (-) 462 WP_000796047.1 NUDIX hydrolase -
  AMM49_RS06250 (AMM49_06235) mutX 1222958..1223440 (-) 483 WP_000163512.1 NUDIX hydrolase Machinery gene
  AMM49_RS06255 (AMM49_06240) hylB 1223657..1226869 (+) 3213 WP_060914835.1 hyaluronate lyase -
  AMM49_RS06260 (AMM49_06245) rfbB 1226921..1227967 (-) 1047 WP_000134275.1 dTDP-glucose 4,6-dehydratase -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18837.23 Da        Isoelectric Point: 4.5116

>NTDB_id=133768 AMM49_RS06250 WP_000163512.1 1222958..1223440(-) (mutX) [Streptococcus agalactiae strain NGBS128]
MTKLATICYIDNGKELLLLHRNKKENDVHEGKWISVGGKLEAGETPDECAKREILEETHLTVKKMDFKGVITFPEFTPGH
DWYTYVFKVTDYEGELISDDESREGTLEWVPYDQVLSKPTWQGDYEIFKWILEDVPFFSAKFVYDEHQNLIEKTVNFYEK

Nucleotide


Download         Length: 483 bp        

>NTDB_id=133768 AMM49_RS06250 WP_000163512.1 1222958..1223440(-) (mutX) [Streptococcus agalactiae strain NGBS128]
ATGACTAAATTAGCAACAATTTGTTACATTGACAATGGCAAGGAATTACTTCTATTGCATCGCAACAAAAAAGAGAATGA
TGTTCATGAGGGAAAGTGGATCTCGGTAGGCGGTAAACTGGAGGCAGGTGAAACTCCGGATGAATGTGCTAAGCGTGAAA
TTCTAGAAGAAACCCATTTAACAGTAAAAAAAATGGATTTTAAAGGAGTCATCACTTTTCCTGAATTTACGCCAGGTCAT
GATTGGTATACCTATGTCTTTAAAGTAACAGATTATGAAGGAGAGTTAATTTCAGATGATGAATCACGAGAAGGAACCTT
AGAATGGGTACCATATGATCAAGTTCTCTCTAAGCCAACGTGGCAAGGAGATTACGAAATTTTTAAATGGATTTTAGAAG
ATGTTCCTTTCTTTTCTGCTAAGTTTGTTTATGATGAACACCAAAATTTAATTGAAAAGACGGTTAATTTTTATGAAAAA
TAG

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(3-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DZB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

71.698

99.375

0.712

Multiple sequence alignment