Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   QI18_RS03120 Genome accession   NZ_CP010050
Coordinates   601821..604271 (+) Length   816 a.a.
NCBI ID   WP_039114770.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 596821..609271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QI18_RS03095 (QI18_03095) - 597585..598097 (+) 513 WP_012897343.1 adenine phosphoribosyltransferase -
  QI18_RS03100 (QI18_03100) rpoE 598314..598877 (+) 564 WP_012897344.1 DNA-directed RNA polymerase subunit delta -
  QI18_RS03105 (QI18_03105) mltG 599014..600666 (+) 1653 WP_039114768.1 endolytic transglycosylase MltG -
  QI18_RS03110 (QI18_03110) greA 600726..601199 (+) 474 WP_025016857.1 transcription elongation factor GreA -
  QI18_RS03115 (QI18_03115) - 601376..601831 (+) 456 WP_010905471.1 CtsR family transcriptional regulator -
  QI18_RS03120 (QI18_03120) clpC 601821..604271 (+) 2451 WP_039114770.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  QI18_RS03125 (QI18_03125) hpf 604406..604963 (+) 558 WP_003129564.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  QI18_RS03130 (QI18_03130) eno 605148..606449 (+) 1302 WP_010905473.1 surface-displayed alpha-enolase -
  QI18_RS03135 (QI18_03135) - 606564..607235 (-) 672 WP_010905491.1 ABC transporter ATP-binding protein -
  QI18_RS03140 (QI18_03140) - 607238..608311 (-) 1074 WP_003129569.1 ABC transporter permease -
  QI18_RS03145 (QI18_03145) - 608323..608892 (-) 570 WP_039114777.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90412.74 Da        Isoelectric Point: 6.3382

>NTDB_id=133708 QI18_RS03120 WP_039114770.1 601821..604271(+) (clpC) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILQGLREKFEDYHQVEFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQTKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVDKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEVGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=133708 QI18_RS03120 WP_039114770.1 601821..604271(+) (clpC) [Lactococcus lactis subsp. lactis strain S0 isolate fresh raw milk]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTATGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCTCATTTACTAGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAAGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCAGAAGCCGTTGGAAC
AGAACACTTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTGAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGTAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGCTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCTCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCCTTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATCGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAAGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGACGAGCCAAGTCCAGATGAAGCGATTGCTATCTTGCAAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGGAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTCCGTTATATGACTAGCCGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCAGTGAAAATTTCTGTCAAAAATCAACAAACAAAACG
TCTTGATTTAGAAAAAGAATTAGCGGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAACTTGATATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCCGGTGTTGCTGACAGCCGTCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAGTGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCTGTTGTTCTTTTAGATGAAGTCGATAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGTAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CACTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCGTCAGCGGTGAAATTAATTGCTGAGGTAGGTTTTGACCCAGAATATGGTGCACGTCCGC
TCCGCAAGGCTCTTCAAAAAGAAGTTGAAGACCTTTTAAGTGAACAATTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGGGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(218-334)

AAA lid domain (AAA_lid_9)

(357-453)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(19-69)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(96-144)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

99.755

100

0.998
  clpC Streptococcus thermophilus LMD-9

50.421

100

0.513
  clpC Streptococcus thermophilus LMG 18311

50.301

100

0.512
  clpC Streptococcus pneumoniae D39

48.678

100

0.496
  clpC Streptococcus pneumoniae Rx1

48.678

100

0.496
  clpC Streptococcus pneumoniae TIGR4

48.558

100

0.495
  clpC Bacillus subtilis subsp. subtilis str. 168

50.374

98.284

0.495
  clpC Streptococcus mutans UA159

48.438

100

0.494
  clpE Streptococcus mutans UA159

47.538

79.657

0.379
  clpC Lactococcus lactis subsp. cremoris KW2

46.718

80.27

0.375
  clpE Streptococcus pneumoniae TIGR4

47.528

76.838

0.365
  clpE Streptococcus pneumoniae Rx1

47.528

76.838

0.365
  clpE Streptococcus pneumoniae D39

47.528

76.838

0.365
  clpE Streptococcus pneumoniae R6

47.528

76.838

0.365

Multiple sequence alignment