Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxS   Type   Regulator
Locus tag   WUE2121_RS10450 Genome accession   NZ_CP012394
Coordinates   2011790..2012296 (+) Length   168 a.a.
NCBI ID   WP_002218101.1    Uniprot ID   A1KW60
Organism   Neisseria meningitidis strain WUE2121     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 2006790..2017296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WUE2121_RS10420 (WUE2121_1971) - 2006973..2007626 (+) 654 WP_002248161.1 IS1595-like element IS1016C family transposase -
  WUE2121_RS10425 (WUE2121_1972) - 2007839..2009374 (+) 1536 WP_002221654.1 sodium-dependent transporter -
  WUE2121_RS13145 (WUE2121_1973) - 2009371..2009463 (+) 93 WP_002233157.1 methionine/alanine import family NSS transporter small subunit -
  WUE2121_RS10430 (WUE2121_1974) lysA 2009499..2010743 (-) 1245 WP_002221655.1 diaminopimelate decarboxylase -
  WUE2121_RS10435 (WUE2121_1975) lptM 2010754..2010924 (-) 171 WP_002218098.1 LPS translocon maturation chaperone LptM -
  WUE2121_RS10440 (WUE2121_1976) cyaY 2010995..2011318 (+) 324 WP_002218099.1 iron donor protein CyaY -
  WUE2121_RS10445 (WUE2121_1977) - 2011349..2011768 (+) 420 WP_002218100.1 DUF2251 domain-containing protein -
  WUE2121_RS10450 (WUE2121_1978) luxS 2011790..2012296 (+) 507 WP_002218101.1 S-ribosylhomocysteine lyase Regulator
  WUE2121_RS10455 (WUE2121_1979) polA 2012442..2015234 (+) 2793 WP_002224673.1 DNA polymerase I -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 18683.41 Da        Isoelectric Point: 5.5451

>NTDB_id=133595 WUE2121_RS10450 WP_002218101.1 2011790..2012296(+) (luxS) [Neisseria meningitidis strain WUE2121]
MPLLDSFKVDHTRMHAPAVRVAKTMTTPKGDTITVFDLRFCIPNKEILPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISP
MGCRTGFYMSLIGTPSEQQVADAWLASMQDVGNVKDQSKIPELNEYQCGTYQMHSLAEAQQIAQNVLARKVAVNKNEELT
LDEGLLNA

Nucleotide


Download         Length: 507 bp        

>NTDB_id=133595 WUE2121_RS10450 WP_002218101.1 2011790..2012296(+) (luxS) [Neisseria meningitidis strain WUE2121]
ATGCCCCTACTAGACAGTTTCAAAGTCGATCACACCCGTATGCATGCCCCCGCCGTACGCGTGGCGAAAACCATGACCAC
GCCCAAAGGCGACACCATTACCGTGTTCGACCTGCGCTTTTGCATTCCCAACAAAGAAATCCTGCCTGAAAAAGGCATAC
ACACGCTGGAGCATTTGTTCGCAGGTTTTATGCGCGACCACTTGAACGGCAACGGCGTGGAAATCATCGACATTTCCCCG
ATGGGCTGCCGCACCGGTTTCTACATGAGCCTTATCGGCACGCCTTCCGAACAGCAGGTCGCCGATGCATGGCTCGCCTC
GATGCAGGATGTGGGCAATGTCAAAGACCAAAGCAAAATCCCCGAGTTGAACGAATACCAATGCGGCACTTATCAAATGC
ACTCGCTCGCCGAAGCGCAGCAAATCGCGCAAAACGTGTTGGCGCGCAAAGTGGCGGTGAACAAAAACGAAGAGCTGACG
CTGGATGAAGGGCTGCTGAACGCCTAA

Domains

Predicted by InterProScan.

S-Ribosylhomocysteinase (LuxS) (LuxS)

(4-153)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1KW60

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxS Vibrio cholerae strain A1552

76.647

99.405

0.762

Multiple sequence alignment