Detailed information NTG0133579

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: WUE2121_RS07580
• Genome accession: NZ_CP012394
• Coordinates: 1439796..1442375 (+)
• Length: 859 a.a.
• NCBI ID: WP_002248083.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain WUE2121
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1434796..1447375

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WUE2121_RS07555 (WUE2121_1431)	-	1434907..1435638 (+)	732	WP_002220620.1	surface lipoprotein assembly modifier	-
WUE2121_RS07560 (WUE2121_1432)	ppx	1435755..1437263 (+)	1509	WP_002220619.1	exopolyphosphatase	-
WUE2121_RS07565 (WUE2121_1433)	-	1437472..1437858 (-)	387	WP_002254830.1	Ag473 family lipoprotein	-
WUE2121_RS07570 (WUE2121_1434)	-	1438178..1438519 (-)	342	WP_002220616.1	hypothetical protein	-
WUE2121_RS07575 (WUE2121_1435)	trpS	1438525..1439535 (-)	1011	WP_002226234.1	tryptophan--tRNA ligase	-
WUE2121_RS07580 (WUE2121_1436)	clpC	1439796..1442375 (+)	2580	WP_002248083.1	ATP-dependent chaperone ClpB	Regulator
WUE2121_RS07585 (WUE2121_1437)	-	1442462..1443676 (-)	1215	WP_002220612.1	pyridoxal phosphate-dependent aminotransferase	-
WUE2121_RS07590 (WUE2121_1438)	-	1443765..1443974 (-)	210	WP_002212949.1	tautomerase family protein	-
WUE2121_RS07595 (WUE2121_1439)	-	1444319..1445125 (+)	807	WP_002212946.1	DUF4198 domain-containing protein	-
WUE2121_RS07600 (WUE2121_1440)	-	1445183..1446448 (-)	1266	WP_002221776.1	Glu/Leu/Phe/Val family dehydrogenase	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95033.49 Da
• Isoelectric Point: 5.3089

>NTDB_id=133579 WUE2121_RS07580 WP_002248083.1 1439796..1442375(+) (clpC) [Neisseria meningitidis strain WUE2121]
MRYDKLTAKFQQALAEAQSLALAADGSCLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGIQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=133579 WUE2121_RS07580 WP_002248083.1 1439796..1442375(+) (clpC) [Neisseria meningitidis strain WUE2121]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAGGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTGTCTGGAAGCGGGCTTTGTGCTGAAAGCCCTGCTTGACGACCAAAACAGCGGTGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAC
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCCGCAACCAAACGCGGCGATGCCTATATCGC
CAGTGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATTTTGAAAGAAGCCGGCGCGACCGAAC
AAAACATCAATGCCGCGATTGACGCGGTACGAGGAGGACAAAACGTGAACGATGCCAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATATACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGCCGTGACGACGAAAT
CCGCCGTGCGATTCAGGTATTGCAACGCCGTACCAAAAACAACCCTGTGCTGATTGGCGAACCGGGCGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCACAACGCATCGTCAACGGCGAAGTACCCGAATCCCTGCGCAACAAACGCCTACTGGTTTTG
GACTTGGCGGCATTGATTGCCGGCGCGAAATACCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGACTTGGC
GAAAGACGACGGCAACACTCTGATTTTCATCGACGAAATCCATACTTTGGTCGGCGCAGGCAAAACCGACGGTGCGATGG
ATGCGGGCAATATGCTGAAACCGGCTTTGGCACGTGGCGAATTGCACTGTATCGGCGCGACCACCTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTTGGCGAGCCAAGTGTAGAAGACACCAT
CGCTATCTTGCGCGGTTTACAGGAGCGTTATGAAATCCACCACGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCTGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAGGTGGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GACAAACTGCTGAAAATGGAAGAAGTATTGCACCGCCGCGTGGTCGGACAGGACGAAGCCGTGCGTGCCGTGTCCGACGC
TATCCGCCGCAGCCGCTCCGGTCTTGCCGATCCGAACAAACCTTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAAACCGAGTTGTGTAAAGCCCTGGCAGGCTTTCTGTTCGACAGCGAAGATCATCTGATTCGCATCGATATGTCCGAA
TATATGGAAAAACACGCCGTTGCACGCCTGATCGGTGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
CGAACAAGTGCGCCGCAAACCGTACAGCGTGATTCTGCTGGACGAAGTGGAAAAAGCCCATCCCGATGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGGCAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCATTCAGGATTACGAAGCGGTAAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGTTTGGATCAGGCAAACA
TCCGCAGCATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCACTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• AAA lid domain (AAA_lid_9) (342-442)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.902	100	0.44
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.504	100	0.402
clpC	Streptococcus pneumoniae TIGR4	41.026	95.343	0.391
clpC	Streptococcus pneumoniae Rx1	41.026	95.343	0.391
clpC	Streptococcus pneumoniae D39	41.026	95.343	0.391
clpC	Lactococcus lactis subsp. cremoris KW2	47.118	80.792	0.381
clpE	Streptococcus pneumoniae TIGR4	47.206	79.162	0.374